GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites ▼	No. of GlyTouCan IDs	GO Labels	GO IDs
Receptor-type tyrosine-protein phosphatase eta	Q9W6V5	PTPRJ		PTPRJ	Gallus gallus	9031	37		cell-cell junction dephosphorylation negative regulation of MAP kinase activity negative regulation of T cell receptor signaling pathway negative regulation of epidermal growth factor receptor signaling pathway negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatase activity plasma membrane platelet-derived growth factor receptor signaling pathway positive regulation of cell adhesion positive regulation of focal adhesion assembly protein modification process protein tyrosine phosphatase activity ruffle membrane	GO:0004725 GO:0005886 GO:0005911 GO:0016311 GO:0016791 GO:0032587 GO:0036211 GO:0042059 GO:0043407 GO:0045785 GO:0048008 GO:0050860 GO:0051894 GO:0051898
Glucosylceramide transporter ABCA12	Q86UK0	ABCA12	ABC12	ABCA12 ABC12	Homo sapiens	9606	37	2	ABC-type transporter activity ATP binding ATP hydrolysis activity ATPase-coupled intramembrane lipid transporter activity ATPase-coupled lipid transmembrane transporter activity ATPase-coupled transmembrane transporter activity Golgi membrane apolipoprotein A-I receptor binding cellular homeostasis ceramide metabolic process ceramide transport cholesterol efflux corneocyte desquamation cytoplasm cytosol epidermal lamellar body epidermal lamellar body membrane establishment of skin barrier intracellular membrane-bounded organelle intracellular protein transport keratinization lipid homeostasis lipid transport lipid transporter activity lung alveolus development membrane phospholipid efflux plasma membrane positive regulation of cholesterol efflux positive regulation of intracellular lipid transport positive regulation of protein localization to cell surface protein localization to plasma membrane regulated exocytosis regulation of insulin secretion involved in cellular response to glucose stimulus regulation of keratinocyte differentiation secretion by cell signaling receptor binding surfactant homeostasis transport vesicle membrane	GO:0000139 GO:0003336 GO:0005102 GO:0005319 GO:0005524 GO:0005737 GO:0005829 GO:0005886 GO:0006672 GO:0006869 GO:0006886 GO:0010875 GO:0016020 GO:0016887 GO:0019725 GO:0030658 GO:0031424 GO:0032379 GO:0032940 GO:0033344 GO:0033700 GO:0034040 GO:0034191 GO:0035627 GO:0042626 GO:0043129 GO:0043231 GO:0045055 GO:0045616 GO:0048286 GO:0055088 GO:0061178 GO:0061436 GO:0072659 GO:0097209 GO:0097234 GO:0140326 GO:0140359 GO:2000010
Proto-oncogene tyrosine-protein kinase ROS	P08941	ROS1		ROS1	Gallus gallus	9031	37		ATP binding cell differentiation columnar/cuboidal epithelial cell development plasma membrane protein phosphorylation protein tyrosine kinase activity receptor complex regulation of ERK1 and ERK2 cascade regulation of TOR signaling regulation of cell growth transmembrane receptor protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase signaling pathway	GO:0001558 GO:0002066 GO:0004713 GO:0004714 GO:0005524 GO:0005886 GO:0006468 GO:0007169 GO:0030154 GO:0032006 GO:0043235 GO:0070372
Protocadherin Fat 2	O88277	Fat2	Fath2 Megf1	Fat2 Fath2 Megf1	Rattus norvegicus	10116	37		Golgi apparatus adherens junction calcium ion binding cell-cell adhesion cell-substrate adhesion epithelial cell migration homophilic cell adhesion via plasma membrane adhesion molecules plasma membrane	GO:0005509 GO:0005794 GO:0005886 GO:0005912 GO:0007156 GO:0010631 GO:0031589 GO:0098609
Fibrillin-1	Q61554	Fbn1	Fbn-1	Fbn1 Fbn-1	Mus musculus	10090	37	1	anatomical structure morphogenesis basement membrane calcium ion binding camera-type eye development cell adhesion mediated by integrin cellular response to insulin-like growth factor stimulus cellular response to transforming growth factor beta stimulus collagen-containing extracellular matrix embryonic eye morphogenesis extracellular matrix extracellular matrix structural constituent extracellular region extracellular space glucose homeostasis glucose metabolic process heart development heparin binding hormone activity identical protein binding integrin binding kidney development metanephros development microfibril negative regulation of osteoclast development negative regulation of osteoclast differentiation post-embryonic eye morphogenesis protein kinase A signaling protein-containing complex binding sequestering of BMP in extracellular matrix sequestering of TGFbeta in extracellular matrix skeletal system development	GO:0001501 GO:0001527 GO:0001656 GO:0001822 GO:0005178 GO:0005179 GO:0005201 GO:0005509 GO:0005576 GO:0005604 GO:0005615 GO:0006006 GO:0007507 GO:0008201 GO:0009653 GO:0010737 GO:0031012 GO:0033627 GO:0035582 GO:0035583 GO:0042593 GO:0042802 GO:0043010 GO:0044877 GO:0045671 GO:0048048 GO:0048050 GO:0062023 GO:0071560 GO:1990314 GO:2001205
Pogo transposable element with ZNF domain	Q7Z3K3	POGZ	KIAA0461 SUHW5 ZNF280E ZNF635	POGZ KIAA0461 SUHW5 ZNF280E ZNF635	Homo sapiens	9606	37	2	DNA binding cell division chromatin cytoplasm cytosol double-strand break repair via homologous recombination kinetochore assembly metal ion binding mitotic sister chromatid cohesion nucleoplasm nucleus positive regulation of transcription by RNA polymerase II	GO:0000724 GO:0000785 GO:0003677 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0007064 GO:0045944 GO:0046872 GO:0051301 GO:0051382
CDKN2A-interacting protein	Q9NXV6	CDKN2AIP	CARF	CDKN2AIP CARF	Homo sapiens	9606	37	2	DNA damage response RNA binding granular component negative regulation of cell growth nucleolus nucleoplasm p53 binding positive regulation of cell growth positive regulation of signal transduction regulation of protein stability	GO:0001652 GO:0002039 GO:0003723 GO:0005654 GO:0005730 GO:0006974 GO:0009967 GO:0030307 GO:0030308 GO:0031647
Envelope glycoprotein GP350	P03200	BLLF1		BLLF1	Human herpesvirus 4 strain B95-8	10377	37		host cell membrane membrane virion membrane	GO:0016020 GO:0033644 GO:0055036
Lysosome-associated membrane glycoprotein 1	P11279	LAMP1		LAMP1	Homo sapiens	9606	37	179	Golgi to lysosome transport autolysosome autophagosome membrane azurophil granule membrane cytolytic granule membrane cytoplasm cytosol endosome membrane enzyme binding establishment of protein localization to organelle external side of plasma membrane extracellular exosome ficolin-1-rich granule membrane granzyme-mediated programmed cell death signaling pathway late endosome late endosome membrane lysosomal membrane lysosome melanosome membrane multivesicular body perinuclear region of cytoplasm phagolysosome membrane plasma membrane positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein domain specific binding protein stabilization regulation of organelle transport along microtubule sarcolemma synaptic vesicle virus receptor activity	GO:0000421 GO:0001618 GO:0005737 GO:0005764 GO:0005765 GO:0005770 GO:0005771 GO:0005829 GO:0005886 GO:0008021 GO:0009897 GO:0010008 GO:0016020 GO:0019899 GO:0019904 GO:0031902 GO:0035577 GO:0042383 GO:0042470 GO:0043323 GO:0044754 GO:0045954 GO:0048471 GO:0050821 GO:0061474 GO:0070062 GO:0072594 GO:0090160 GO:0101003 GO:0101004 GO:0140507 GO:1902513
Collagen alpha-1(XVIII) chain	P39060	COL18A1		COL18A1	Homo sapiens	9606	37	11	angiogenesis animal organ morphogenesis basement membrane cell adhesion collagen fibril organization collagen trimer collagen-containing extracellular matrix endoplasmic reticulum lumen endothelial cell morphogenesis extracellular exosome extracellular matrix structural constituent conferring tensile strength extracellular region extracellular space metal ion binding negative regulation of cell population proliferation notochord development response to hydrostatic pressure response to xenobiotic stimulus skeletal system development visual perception	GO:0001501 GO:0001525 GO:0001886 GO:0005576 GO:0005581 GO:0005604 GO:0005615 GO:0005788 GO:0007155 GO:0007601 GO:0008285 GO:0009410 GO:0009887 GO:0030020 GO:0030199 GO:0030903 GO:0046872 GO:0051599 GO:0062023 GO:0070062