GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Angiopoietin-1 receptor	Q06807	TEK	TIE-2 TIE2	TEK TIE-2 TIE2	Bos taurus	9913	1	ATP binding Tie signaling pathway actin filament angiogenesis apical plasma membrane basolateral plasma membrane cell differentiation cell surface cell-cell junction centriolar satellite cytoplasm endothelial cell proliferation extracellular region focal adhesion heart development heart trabecula formation identical protein binding intracellular signal transduction membrane raft microvillus negative regulation of angiogenesis negative regulation of endothelial cell apoptotic process obsolete positive regulation of phosphatidylinositol 3-kinase activity peptidyl-tyrosine phosphorylation positive regulation of ERK1 and ERK2 cascade positive regulation of MAPK cascade positive regulation of angiogenesis positive regulation of endothelial cell migration positive regulation of focal adhesion assembly positive regulation of intracellular signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of protein phosphorylation protein autophosphorylation protein tyrosine kinase activity receptor complex regulation of establishment or maintenance of cell polarity sprouting angiogenesis stress fiber substrate adhesion-dependent cell spreading transmembrane receptor protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase signaling pathway	GO:0001525 GO:0001725 GO:0001934 GO:0001935 GO:0002040 GO:0004713 GO:0004714 GO:0005524 GO:0005576 GO:0005737 GO:0005884 GO:0005902 GO:0005911 GO:0005925 GO:0007169 GO:0007507 GO:0009986 GO:0010595 GO:0016323 GO:0016324 GO:0016525 GO:0018108 GO:0030154 GO:0032878 GO:0034446 GO:0034451 GO:0035556 GO:0042802 GO:0043235 GO:0043410 GO:0043552 GO:0045121 GO:0045766 GO:0046777 GO:0048014 GO:0051894 GO:0051897 GO:0060347 GO:0070374 GO:1902533 GO:2000352
Hyaluronidase	A0A6I9P2K1	LOC104955607		LOC104955607	Notothenia coriiceps	8208	1	carbohydrate metabolic process hyalurononglucosaminidase activity membrane	GO:0004415 GO:0005975 GO:0016020
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase (Fragment)	A0A852E0A1	B3gat2		B3gat2	Vidua macroura	187451	1	Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Netrin G2	A2AKW8	Ntng2		Ntng2	Mus musculus	10090	2
Taste receptor type 2 member 60	Q645U7	TAS2R60		TAS2R60	Pongo pygmaeus	9600	1	G protein-coupled receptor activity plasma membrane sensory perception of taste	GO:0004930 GO:0005886 GO:0050909
Voltage-dependent L-type calcium channel subunit alpha	A0A3Q1C390	CACNA1S		CACNA1S	Amphiprion ocellaris	80972	1	calcium ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005509 GO:0005891 GO:0034765
Glutamate receptor ionotropic, kainate 4	Q5IS46	GRIK4		GRIK4	Pan troglodytes	9598	9	kainate selective glutamate receptor activity kainate selective glutamate receptor complex modulation of chemical synaptic transmission plasma membrane postsynaptic density membrane presynaptic membrane synaptic transmission, glutamatergic transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GO:0005886 GO:0015277 GO:0032983 GO:0035249 GO:0042734 GO:0050804 GO:0098839 GO:1904315
Matrix protein 2	Q464F1	M2	M	M2 M	Influenza A virus (A/New York/386/2004(H3N2))	335335	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Protein patched homolog 1	Q98864	ptch1	ptc1	ptch1 ptc1	Danio rerio	7955	3	camera-type eye development cardioblast differentiation hedgehog family protein binding hedgehog receptor activity negative regulation of muscle organ development negative regulation of smoothened signaling pathway osteoblast differentiation plasma membrane proximal/distal pattern formation retinal ganglion cell axon guidance smoothened binding	GO:0001649 GO:0005119 GO:0005886 GO:0008158 GO:0009954 GO:0010002 GO:0031290 GO:0043010 GO:0045879 GO:0048635 GO:0097108
Rhodopsin	A0A8C5FY47	rho		rho	Gouania willdenowi	441366	2	G protein-coupled receptor activity membrane metal ion binding photoreceptor activity phototransduction visual perception	GO:0004930 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0046872