GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs ▲	GO Labels	GO IDs
ABI family member 3 binding protein	Q59IW6	Abi3bp	TARSH	Abi3bp TARSH	Mus musculus	10090	4	1	actin cytoskeleton organization actin filament binding collagen binding collagen-containing extracellular matrix dendritic shaft dendritic spine extracellular matrix extracellular matrix organization glycosaminoglycan binding heparin binding interstitial matrix lamellipodium positive regulation of cell-substrate adhesion postsynaptic density regulation of dendritic spine morphogenesis regulation of postsynaptic density assembly	GO:0005518 GO:0005539 GO:0005614 GO:0008201 GO:0010811 GO:0014069 GO:0030027 GO:0030036 GO:0030198 GO:0031012 GO:0043197 GO:0043198 GO:0051015 GO:0061001 GO:0062023 GO:0099151
Ubiquitin-associated protein 2	A0A0G2JYI7	Ubap2		Ubap2	Rattus norvegicus	10116		1	cytoplasm nucleus	GO:0005634 GO:0005737
DNA topoisomerase 2	V5BUD4	TCDM_03128		TCDM_03128	Trypanosoma cruzi Dm28c	1416333		1	ATP binding DNA binding DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topological change metal ion binding	GO:0003677 GO:0003918 GO:0005524 GO:0006265 GO:0046872
Uncharacterized protein	V5BLQ8	TCDM_04294		TCDM_04294	Trypanosoma cruzi Dm28c	1416333		1	membrane	GO:0016020
CAP-Gly domain-containing linker protein 4	Q8N3C7	CLIP4	RSNL2	CLIP4 RSNL2	Homo sapiens	9606		1	cell cortex cytoplasmic microtubule organization intracellular membrane-bounded organelle microtubule plus-end microtubule plus-end binding nucleus	GO:0005634 GO:0005938 GO:0031122 GO:0035371 GO:0043231 GO:0051010
Histamine H4 receptor	Q9H3N8	HRH4	GPCR105	HRH4 GPCR105	Homo sapiens	9606	2	1	G protein-coupled acetylcholine receptor activity G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger G protein-coupled serotonin receptor activity adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission dendrite histamine receptor activity inflammatory response plasma membrane positive regulation of cytosolic calcium ion concentration regulation of MAPK cascade synapse	GO:0004969 GO:0004993 GO:0005886 GO:0006954 GO:0007187 GO:0007197 GO:0007204 GO:0007268 GO:0016907 GO:0030425 GO:0043408 GO:0045202
Synapsin-3	O14994	SYN3		SYN3	Homo sapiens	9606	1	1	ATP binding extrinsic component of synaptic vesicle membrane glutamatergic synapse neurotransmitter secretion postsynaptic density regulation of synaptic transmission, GABAergic synaptic vesicle synaptic vesicle clustering synaptic vesicle membrane	GO:0005524 GO:0007269 GO:0008021 GO:0014069 GO:0030672 GO:0032228 GO:0097091 GO:0098850 GO:0098978
Alpha-1,4 glucan phosphorylase	G3V6Y6	Pygb		Pygb	Rattus norvegicus	10116		1	SHG alpha-glucan phosphorylase activity cytoplasm glycogen catabolic process glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity pyridoxal phosphate binding	GO:0005737 GO:0005980 GO:0008184 GO:0030170 GO:0102250 GO:0102499
AKT1 substrate 1 (proline-rich) (Fragment)	D3Z4W3	Akt1s1		Akt1s1	Mus musculus	10090		1	negative regulation of TOR signaling neurotrophin TRK receptor signaling pathway	GO:0032007 GO:0048011
Actin, beta	A0A0G2K3K2	Actb		Actb	Rattus norvegicus	10116		1	NuA4 histone acetyltransferase complex Schaffer collateral - CA1 synapse Tat protein binding adherens junction adherens junction assembly apical junction complex apical protein localization brush border calyx of Held cell motility cellular response to cytochalasin B cortical cytoskeleton cytoplasmic ribonucleoprotein granule cytosol establishment or maintenance of cell polarity glutamatergic synapse identical protein binding kinesin binding lamellipodium morphogenesis of a polarized epithelium nitric-oxide synthase binding nucleosome nucleus positive regulation of double-strand break repair via homologous recombination postsynaptic actin cytoskeleton protein kinase binding protein localization to adherens junction regulation of cell cycle regulation of norepinephrine uptake regulation of protein localization to plasma membrane regulation of synaptic vesicle endocytosis regulation of transepithelial transport ribonucleoprotein complex structural constituent of postsynaptic actin cytoskeleton tight junction	GO:0000786 GO:0001738 GO:0005634 GO:0005829 GO:0005903 GO:0005912 GO:0007163 GO:0019894 GO:0019901 GO:0030027 GO:0030863 GO:0030957 GO:0034333 GO:0035267 GO:0036464 GO:0042802 GO:0043296 GO:0044305 GO:0045176 GO:0048870 GO:0050998 GO:0051621 GO:0051726 GO:0070160 GO:0071896 GO:0072749 GO:0098685 GO:0098871 GO:0098973 GO:0098978 GO:0150111 GO:1900242 GO:1903076 GO:1905168 GO:1990904