GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID Gene Symbol Gene Symbol Aliases ▼ Gene Symbol All Species Taxonomy ID No. of Glycosylation Sites No. of GlyTouCan IDs MCAW IDs Disease Name Aliases Disease Name GO Labels GO IDs
  • smp-1
  • sema-1a
  • smp-1
  • sema-1a
6239
6
  • axon guidance
  • chemorepellent activity
  • membrane
  • negative chemotaxis
  • negative regulation of axon extension involved in axon guidance
  • nematode male tail mating organ morphogenesis
  • positive regulation of cell migration
  • semaphorin receptor binding
  • semaphorin-plexin signaling pathway
  • GO:0007411
  • GO:0016020
  • GO:0030215
  • GO:0030335
  • GO:0045499
  • GO:0048843
  • GO:0050919
  • GO:0071526
  • GO:0090597
  • epha4-a
  • sek1
  • epha4-a
  • sek1
8355
2
  • ATP binding
  • GPI-linked ephrin receptor activity
  • cell adhesion
  • early endosome membrane
  • nervous system development
  • phosphorylation
  • plasma membrane
  • regulation of GTPase activity
  • transmembrane-ephrin receptor activity
  • GO:0005004
  • GO:0005005
  • GO:0005524
  • GO:0005886
  • GO:0007155
  • GO:0007399
  • GO:0016310
  • GO:0031901
  • GO:0043087
  • sed5
  • sedE
  • sed5
  • sedE
330879
2
  • endopeptidase activity
  • extracellular space
  • metal ion binding
  • proteolysis
  • serine-type endopeptidase activity
  • tripeptidyl-peptidase activity
  • GO:0004175
  • GO:0004252
  • GO:0005615
  • GO:0006508
  • GO:0008240
  • GO:0046872
  • sed4
  • sedD
  • sed4
  • sedD
330879
4
  • endopeptidase activity
  • extracellular space
  • metal ion binding
  • proteolysis
  • serine-type endopeptidase activity
  • tripeptidyl-peptidase activity
  • GO:0004175
  • GO:0004252
  • GO:0005615
  • GO:0006508
  • GO:0008240
  • GO:0046872
  • sed3
  • sedC
  • sed3
  • sedC
330879
6
  • endopeptidase activity
  • extracellular space
  • metal ion binding
  • proteolysis
  • serine-type endopeptidase activity
  • tripeptidyl-peptidase activity
  • GO:0004175
  • GO:0004252
  • GO:0005615
  • GO:0006508
  • GO:0008240
  • GO:0046872
  • sed2
  • sedB
  • sed2
  • sedB
330879
3
  • endopeptidase activity
  • extracellular space
  • metal ion binding
  • proteolysis
  • serine-type endopeptidase activity
  • tripeptidyl-peptidase activity
  • GO:0004175
  • GO:0004252
  • GO:0005615
  • GO:0006508
  • GO:0008240
  • GO:0046872
  • sed1
  • sedA
  • sed1
  • sedA
330879
4
  • endopeptidase activity
  • extracellular space
  • metal ion binding
  • proteolysis
  • serine-type endopeptidase activity
  • tripeptidyl-peptidase activity
  • GO:0004175
  • GO:0004252
  • GO:0005615
  • GO:0006508
  • GO:0008240
  • GO:0046872
  • pdfr-1
  • seb-1
  • pdfr-1
  • seb-1
6239
5
  • G protein-coupled peptide receptor activity
  • adenylate cyclase-activating G protein-coupled receptor signaling pathway
  • adenylate cyclase-modulating G protein-coupled receptor signaling pathway
  • calcitonin family receptor activity
  • calcitonin receptor activity
  • cell surface receptor signaling pathway
  • intracellular calcium ion homeostasis
  • locomotion
  • locomotion involved in locomotory behavior
  • locomotory exploration behavior
  • male mating behavior
  • plasma membrane
  • positive regulation of adenylate cyclase activity
  • positive regulation of gene expression
  • sleep
  • GO:0004948
  • GO:0005886
  • GO:0006874
  • GO:0007166
  • GO:0007188
  • GO:0007189
  • GO:0008528
  • GO:0010628
  • GO:0030431
  • GO:0031987
  • GO:0035641
  • GO:0040011
  • GO:0045762
  • GO:0060179
  • GO:0097642
  • helC
  • sdr1
  • helC
  • sdr1
330879
2
  • cytoplasm
  • helvolic acid biosynthetic process
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
  • secondary metabolic process
  • GO:0005737
  • GO:0016616
  • GO:0019748
  • GO:1900812
  • sdc4-b
  • sdc4.2
  • sdc4-b
  • sdc4.2
8355
3
  • Wnt signaling pathway
  • convergent extension involved in gastrulation
  • frizzled binding
  • membrane
  • neural tube closure
  • protein localization
  • GO:0001843
  • GO:0005109
  • GO:0008104
  • GO:0016020
  • GO:0016055
  • GO:0060027
Displaying entries 211 - 220 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01