GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs ▲	GO Labels	GO IDs
Protein disulfide-isomerase	Q4E3F7	Tc00.1047053507611.370		Tc00.1047053507611.370	Trypanosoma cruzi strain CL Brener	353153		1	endoplasmic reticulum lumen protein disulfide isomerase activity	GO:0003756 GO:0005788
Protein MTSS 1	Q8R1S4	Mtss1	Mim	Mtss1 Mim	Mus musculus	10090	4	1	actin binding actin cytoskeleton actin filament binding actin filament organization actin filament polymerization actin monomer binding adherens junction adherens junction maintenance bone mineralization cellular response to fluid shear stress cytoplasm epithelial cell proliferation involved in renal tubule morphogenesis glomerulus morphogenesis identical protein binding in utero embryonic development magnesium ion homeostasis metanephric tubule development muscle organ development negative regulation of epithelial cell proliferation nephron tubule epithelial cell differentiation nervous system development phospholipid binding plasma membrane organization positive regulation of actin filament bundle assembly renal tubule morphogenesis signaling receptor binding	GO:0001701 GO:0003779 GO:0003785 GO:0005102 GO:0005543 GO:0005737 GO:0005912 GO:0007009 GO:0007015 GO:0007399 GO:0007517 GO:0010960 GO:0015629 GO:0030041 GO:0030282 GO:0032233 GO:0034334 GO:0042802 GO:0050680 GO:0051015 GO:0061333 GO:0071498 GO:0072102 GO:0072160 GO:0072170 GO:2001013
Adenosine kinase	V5B941	TCDM_01513		TCDM_01513	Trypanosoma cruzi Dm28c	1416333		1	AMP salvage ATP binding adenosine kinase activity phosphorylation purine ribonucleoside salvage	GO:0004001 GO:0005524 GO:0006166 GO:0016310 GO:0044209
Ataxin-1	P54253	ATXN1	ATX1 SCA1	ATXN1 ATX1 SCA1	Homo sapiens	9606	7	1	DNA binding RNA processing brain development cytoplasm cytosol identical protein binding learning memory negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nervous system development nuclear export nuclear inclusion body nuclear matrix nucleolus nucleoplasm nucleus poly(G) binding poly(U) RNA binding protein self-association social behavior	GO:0000122 GO:0003677 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0006396 GO:0007399 GO:0007420 GO:0007612 GO:0007613 GO:0008266 GO:0016363 GO:0034046 GO:0035176 GO:0042405 GO:0042802 GO:0043621 GO:0045892 GO:0051168
Isocitrate dehydrogenase [NADP], mitochondrial	P56574	Idh2		Idh2	Rattus norvegicus	10116	4	1	2-oxoglutarate metabolic process NAD binding NADP biosynthetic process NADP metabolic process cytosol glyoxylate cycle isocitrate dehydrogenase (NADP+) activity isocitrate metabolic process magnesium ion binding mitochondrion negative regulation of glial cell migration negative regulation of glial cell proliferation negative regulation of matrix metallopeptidase secretion peroxisome tricarboxylic acid cycle	GO:0000287 GO:0004450 GO:0005739 GO:0005777 GO:0005829 GO:0006097 GO:0006099 GO:0006102 GO:0006103 GO:0006739 GO:0006741 GO:0051287 GO:0060253 GO:1903976 GO:1904465
Hexosyltransferase	Q4D9P7	Tc00.1047053511395.120		Tc00.1047053511395.120	Trypanosoma cruzi strain CL Brener	353153		1	Golgi membrane hexosyltransferase activity	GO:0000139 GO:0016758
Leucine-rich repeat-containing protein 74A	Q0VAA2	LRRC74A	C14orf166B LRRC74	LRRC74A C14orf166B LRRC74	Homo sapiens	9606		1
C2 calcium-dependent domain containing 5	A0A0N4SW93	C2cd5		C2cd5	Mus musculus	10090		1	calcium ion binding calcium-dependent phospholipid binding cell cortex cellular response to insulin stimulus centriolar satellite cytoplasmic vesicle membrane cytosol intracellular protein transmembrane transport positive regulation of protein targeting to membrane positive regulation of vesicle fusion ruffle membrane	GO:0005509 GO:0005544 GO:0005829 GO:0005938 GO:0030659 GO:0031340 GO:0032587 GO:0032869 GO:0034451 GO:0065002 GO:0090314
Trichohyalin-like protein 1	Q5QJ38	TCHHL1	S100A17 THHL1	TCHHL1 S100A17 THHL1	Homo sapiens	9606	2	1	transition metal ion binding	GO:0046914
Eukaryotic initiation factor 4A-II	P10630	Eif4a2	Ddx2b	Eif4a2 Ddx2b	Mus musculus	10090		1	ATP binding ATP hydrolysis activity RNA binding RNA helicase activity cellular response to leukemia inhibitory factor cytoplasmic translational initiation eukaryotic translation initiation factor 4F complex perinuclear region of cytoplasm translation initiation factor activity translational initiation	GO:0002183 GO:0003723 GO:0003724 GO:0003743 GO:0005524 GO:0006413 GO:0016281 GO:0016887 GO:0048471 GO:1990830