GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs ▲	GO Labels	GO IDs
Transmembrane channel-like protein 2	Q8R4P4	Tmc2		Tmc2	Mus musculus	10090		1	calcium ion transmembrane transport detection of mechanical stimulus involved in sensory perception of sound mechanosensitive monoatomic ion channel activity plasma membrane regulation of calcium ion transmembrane transport stereocilium tip vestibular reflex voltage-gated calcium channel activity	GO:0005245 GO:0005886 GO:0008381 GO:0032426 GO:0050910 GO:0060005 GO:0070588 GO:1903169
Methionine synthase reductase	Q9UBK8	MTRR		MTRR	Homo sapiens	9606		1	DNA methylation FAD binding FMN binding NADPH binding NADPH-hemoprotein reductase activity S-adenosylmethionine cycle [methionine synthase] reductase activity cytosol flavin adenine dinucleotide binding folic acid metabolic process homocysteine catabolic process homocysteine metabolic process intermediate filament cytoskeleton methionine biosynthetic process negative regulation of cystathionine beta-synthase activity nucleoplasm oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor	GO:0003958 GO:0005654 GO:0005829 GO:0006306 GO:0009086 GO:0010181 GO:0016723 GO:0030586 GO:0033353 GO:0043418 GO:0045111 GO:0046655 GO:0050660 GO:0050667 GO:0070402 GO:0071949 GO:1904042
Phosphatidylinositol polyphosphate 5-phosphatase type IV	Q9NRR6	INPP5E		INPP5E	Homo sapiens	9606		1	Golgi apparatus Golgi cisterna membrane Golgi membrane axoneme cilium cytosol inositol-polyphosphate 5-phosphatase activity negative regulation of protein localization to cilium negative regulation of translation nucleus phosphatidylinositol biosynthetic process phosphatidylinositol dephosphorylation phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity plasma membrane ruffle	GO:0000139 GO:0001726 GO:0004439 GO:0004445 GO:0005634 GO:0005794 GO:0005829 GO:0005886 GO:0005929 GO:0005930 GO:0006661 GO:0016314 GO:0017148 GO:0032580 GO:0034485 GO:0043813 GO:0046856 GO:1903565
Armadillo-like helical domain containing protein 1	Q6PIY5	ARMH1	C1orf228 NCRNA00082	ARMH1 C1orf228 NCRNA00082	Homo sapiens	9606		1
DNA replication licensing factor MCM3	P25205	MCM3		MCM3	Homo sapiens	9606	2	1	ATP binding ATP hydrolysis activity CMG complex DNA binding DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication MCM complex alpha DNA polymerase:primase complex centrosome chromosome, telomeric region double-strand break repair via break-induced replication helicase activity membrane mitotic DNA replication initiation nucleoplasm nucleus perinuclear region of cytoplasm regulation of DNA-templated DNA replication initiation single-stranded DNA binding	GO:0000727 GO:0000781 GO:0003677 GO:0003697 GO:0004386 GO:0005524 GO:0005634 GO:0005654 GO:0005658 GO:0005813 GO:0006268 GO:0006270 GO:0006271 GO:0016020 GO:0016887 GO:0030174 GO:0042555 GO:0048471 GO:0071162 GO:1902975
aspartate--tRNA ligase	V5AS93	TCDM_08491		TCDM_08491	Trypanosoma cruzi Dm28c	1416333		1	ATP binding aspartate-tRNA ligase activity aspartyl-tRNA aminoacylation cytoplasm nucleic acid binding	GO:0003676 GO:0004815 GO:0005524 GO:0005737 GO:0006422
Protein aurora borealis	Q6PGQ7	BORA	C13orf34	BORA C13orf34	Homo sapiens	9606		1	cell cycle cell division cytoplasm cytosol meiotic spindle nucleus protein kinase binding regulation of mitotic nuclear division regulation of mitotic spindle organization regulation of protein localization	GO:0005634 GO:0005737 GO:0005829 GO:0007049 GO:0007088 GO:0019901 GO:0032880 GO:0051301 GO:0060236 GO:0072687
Netrin receptor DCC	P43146	DCC	IGDCC1	DCC IGDCC1	Homo sapiens	9606	6	1	Schaffer collateral - CA1 synapse anterior/posterior axon guidance apoptotic process axon guidance axonal growth cone axonogenesis cell surface cell-cell adhesion cytosol dorsal/ventral axon guidance negative regulation of collateral sprouting negative regulation of dendrite development negative regulation of neuron projection development neuron migration plasma membrane postsynaptic density membrane postsynaptic modulation of chemical synaptic transmission spinal cord ventral commissure morphogenesis transmembrane signaling receptor activity	GO:0001764 GO:0004888 GO:0005829 GO:0005886 GO:0006915 GO:0007409 GO:0007411 GO:0009986 GO:0010977 GO:0021965 GO:0033563 GO:0033564 GO:0044295 GO:0048671 GO:0098609 GO:0098685 GO:0098839 GO:0099170 GO:2000171
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	O94760	DDAH1	DDAH	DDAH1 DDAH	Homo sapiens	9606		1	amino acid binding arginine catabolic process arginine metabolic process catalytic activity citrulline metabolic process cytosol dimethylargininase activity extracellular exosome metal ion binding negative regulation of cell population proliferation negative regulation of cellular response to hypoxia negative regulation of vascular permeability nitric oxide mediated signal transduction nitric oxide metabolic process positive regulation of angiogenesis positive regulation of nitric oxide biosynthetic process regulation of systemic arterial blood pressure	GO:0000052 GO:0003073 GO:0003824 GO:0005829 GO:0006525 GO:0006527 GO:0007263 GO:0008285 GO:0016403 GO:0016597 GO:0043116 GO:0045429 GO:0045766 GO:0046209 GO:0046872 GO:0070062 GO:1900038
Probable eukaryotic initiation factor 4A	K2MZ11	MOQ_003828		MOQ_003828	Trypanosoma cruzi marinkellei	85056		1	ATP binding RNA helicase activity hydrolase activity translation initiation factor activity	GO:0003724 GO:0003743 GO:0005524 GO:0016787