GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	MCAW IDs ▼	GO Labels	GO IDs
Covalently-linked cell wall protein 14	O13547	CCW14	ICWP SSR1	CCW14 ICWP SSR1	Saccharomyces cerevisiae S288C	559292	1		1170	cell periphery extracellular region fungal-type cell wall fungal-type cell wall organization mitochondrion side of membrane structural constituent of cell wall	GO:0005199 GO:0005576 GO:0005739 GO:0009277 GO:0031505 GO:0071944 GO:0098552
Galectin-3	P17931	LGALS3	MAC2	LGALS3 MAC2	Homo sapiens	9606		1	103 104 106 107 108 115 116 5108	IgE binding RNA binding RNA splicing carbohydrate binding cell surface chemoattractant activity collagen-containing extracellular matrix cytoplasm cytosol eosinophil chemotaxis epithelial cell differentiation extracellular exosome extracellular region extracellular space ficolin-1-rich granule membrane immunological synapse innate immune response laminin binding mRNA processing macrophage chemotaxis membrane mitochondrial inner membrane molecular condensate scaffold activity monocyte chemotaxis mononuclear cell migration negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell negative regulation of T cell receptor signaling pathway negative regulation of endocytosis negative regulation of extrinsic apoptotic signaling pathway negative regulation of immunological synapse formation negative regulation of protein tyrosine phosphatase activity neutrophil chemotaxis nucleoplasm nucleus plasma membrane positive chemotaxis positive regulation of calcium ion import positive regulation of mononuclear cell migration positive regulation of protein localization to plasma membrane positive regulation of protein-containing complex assembly protein phosphatase binding protein phosphatase inhibitor activity regulation of T cell apoptotic process regulation of T cell proliferation regulation of extrinsic apoptotic signaling pathway via death domain receptors secretory granule membrane spliceosomal complex	GO:0001772 GO:0002548 GO:0003723 GO:0004864 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005681 GO:0005737 GO:0005743 GO:0005829 GO:0005886 GO:0006397 GO:0008380 GO:0009986 GO:0016020 GO:0019863 GO:0019903 GO:0030246 GO:0030593 GO:0030667 GO:0030855 GO:0031334 GO:0042056 GO:0042129 GO:0043236 GO:0045087 GO:0045806 GO:0048245 GO:0048246 GO:0050860 GO:0050918 GO:0062023 GO:0070062 GO:0070232 GO:0071674 GO:0071677 GO:0090280 GO:0101003 GO:0140693 GO:1902041 GO:1903078 GO:1903614 GO:2000521 GO:2001189 GO:2001237
Matrix protein 2	F8U6F3	M2	M	M2 M	Influenza A virus (A/swine/QC/1488-4/2009(H1N1))	1000311	1			host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Matrix protein 2	E1TWM9	M2	M	M2 M	Influenza A virus (A/California/VRDL270/2009(H1N1))	765505	1			host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Rhodopsin	A0A5N4D0T7	Rhodopsin		Rhodopsin	Camelus dromedarius	9838	2			G protein-coupled receptor activity membrane metal ion binding photoreceptor activity phototransduction visual perception	GO:0004930 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0046872
Putative laccase-5	Q5N9W4	LAC5		LAC5	Oryza sativa Japonica Group	39947	12			apoplast copper ion binding hydroquinone:oxygen oxidoreductase activity lignin catabolic process oxidoreductase activity	GO:0005507 GO:0016491 GO:0046274 GO:0048046 GO:0052716
Pannexin	A0A5E4CV48	PANX		PANX	Marmota monax	9995	1			channel activity gap junction monoatomic cation transport plasma membrane positive regulation of interleukin-1 production	GO:0005886 GO:0005921 GO:0006812 GO:0015267 GO:0032732
Grainyhead-like protein 2 homolog	Q8K5C0	Grhl2	Bom Tcfcp2l3	Grhl2 Bom Tcfcp2l3	Mus musculus	10090	2	1		DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding anterior neural tube closure bicellular tight junction assembly brain development camera-type eye development cardiac ventricle morphogenesis cell adhesion cell junction assembly cell population proliferation cell-cell junction chromatin DNA binding chromatin binding embryonic cranial skeleton morphogenesis embryonic digit morphogenesis embryonic organ development epidermis development epithelial cell morphogenesis epithelial cell morphogenesis involved in placental branching epithelium migration face development identical protein binding in utero embryonic development intronic transcription regulatory region sequence-specific DNA binding lung epithelial cell differentiation lung lobe morphogenesis membrane multicellular organism growth negative regulation of keratinocyte differentiation neural tube closure neural tube development nucleoplasm nucleus positive regulation of DNA-templated transcription positive regulation of telomerase activity positive regulation of transcription by RNA polymerase II regulation of DNA methylation regulation of DNA-templated transcription regulation of gene expression regulation of transcription by RNA polymerase II respiratory tube development sequence-specific DNA binding	GO:0000978 GO:0001161 GO:0001228 GO:0001701 GO:0001843 GO:0003208 GO:0003382 GO:0003677 GO:0003682 GO:0003700 GO:0005634 GO:0005654 GO:0005911 GO:0006355 GO:0006357 GO:0007155 GO:0007420 GO:0008283 GO:0008544 GO:0010468 GO:0016020 GO:0021915 GO:0030323 GO:0031490 GO:0034329 GO:0035264 GO:0042733 GO:0042802 GO:0043010 GO:0043565 GO:0044030 GO:0045617 GO:0045893 GO:0045944 GO:0048568 GO:0048701 GO:0051973 GO:0060324 GO:0060463 GO:0060487 GO:0060672 GO:0061713 GO:0070830 GO:0090132
Beta-casein	P39037	CSN2		CSN2	Sus scrofa	9823	1			extracellular space	GO:0005615
P2X purinoceptor (Fragment)	A0A7L4J621	P2rx5		P2rx5	Pomatorhinus ruficollis	932028	1			ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794