GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites ▼	No. of GlyTouCan IDs	GO Labels	GO IDs
Envelope glycoprotein gp160	P04624	env		env	Human immunodeficiency virus type 1 (HXB3 ISOLATE)	11707	29		clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Laminin subunit alpha-5	Q61001	Lama5		Lama5	Mus musculus	10090	29	16	animal organ morphogenesis axon guidance basement membrane branching involved in salivary gland morphogenesis branching involved in ureteric bud morphogenesis branching morphogenesis of an epithelial tube cell migration cell-cell adhesion cilium assembly collagen-containing extracellular matrix extracellular matrix extracellular matrix of synaptic cleft extracellular region extracellular space glutamatergic synapse hair follicle development integrin binding integrin-mediated signaling pathway kidney development laminin-10 complex laminin-5 complex lung development morphogenesis of a polarized epithelium morphogenesis of embryonic epithelium muscle organ development neural crest cell migration neuromuscular junction odontogenesis of dentin-containing tooth postsynapse organization protein localization to plasma membrane regulation of cell adhesion regulation of cell migration regulation of embryonic development regulation of epithelial cell proliferation skeletal system morphogenesis substrate adhesion-dependent cell spreading synaptic cleft tissue development trunk neural crest cell migration	GO:0001658 GO:0001738 GO:0001755 GO:0001822 GO:0001942 GO:0005178 GO:0005576 GO:0005604 GO:0005610 GO:0005615 GO:0007229 GO:0007411 GO:0007517 GO:0009887 GO:0009888 GO:0016331 GO:0016477 GO:0030155 GO:0030324 GO:0030334 GO:0031012 GO:0031594 GO:0034446 GO:0036484 GO:0042475 GO:0043083 GO:0043259 GO:0045995 GO:0048705 GO:0048754 GO:0050678 GO:0060271 GO:0060445 GO:0062023 GO:0072659 GO:0098609 GO:0098965 GO:0098978 GO:0099173
Amyloid-beta precursor protein	P05067	APP	A4 AD1	APP A4 AD1	Homo sapiens	9606	29	10	COPII-coated ER to Golgi transport vesicle DNA binding G2/M transition of mitotic cell cycle Golgi apparatus Golgi lumen Golgi-associated vesicle Notch signaling pathway PTB domain binding RNA polymerase II cis-regulatory region sequence-specific DNA binding adult locomotory behavior amyloid fibril formation apical part of cell astrocyte activation astrocyte activation involved in immune response axo-dendritic transport axon axon midline choice point recognition axonogenesis cell adhesion cell surface cell-cell junction cellular response to amyloid-beta central nervous system development cholesterol metabolic process ciliary rootlet clathrin-coated pit cognition collateral sprouting in absence of injury cytoplasm cytoplasmic polyadenylation cytosol dendrite development dendritic shaft dendritic spine early endosome endocytosis endoplasmic reticulum endoplasmic reticulum lumen endosome endosome lumen enzyme binding extracellular exosome extracellular matrix organization extracellular region extracellular space forebrain development growth cone heparin binding identical protein binding intracellular copper ion homeostasis ionotropic glutamate receptor signaling pathway learning learning or memory locomotory behavior mRNA polyadenylation mating behavior membrane membrane raft microglia development microglial cell activation modulation of excitatory postsynaptic potential negative regulation of cell population proliferation negative regulation of gene expression negative regulation of long-term synaptic potentiation negative regulation of neuron differentiation neuromuscular junction neuromuscular process controlling balance neuron apoptotic process neuron cellular homeostasis neuron projection development neuron projection maintenance neuron remodeling nuclear envelope lumen perikaryon perinuclear region of cytoplasm plasma membrane platelet alpha granule lumen positive regulation of DNA-binding transcription factor activity positive regulation of ERK1 and ERK2 cascade positive regulation of G2/M transition of mitotic cell cycle positive regulation of JNK cascade positive regulation of T cell migration positive regulation of amyloid fibril formation positive regulation of chemokine production positive regulation of gene expression positive regulation of glycolytic process positive regulation of inflammatory response positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of long-term synaptic potentiation positive regulation of mitotic cell cycle positive regulation of non-canonical NF-kappaB signal transduction positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-threonine phosphorylation positive regulation of protein binding positive regulation of protein metabolic process positive regulation of protein phosphorylation positive regulation of transcription by RNA polymerase II positive regulation of tumor necrosis factor production presynaptic active zone protein phosphorylation receptor complex receptor ligand activity recycling endosome regulation of NMDA receptor activity regulation of Wnt signaling pathway regulation of epidermal growth factor-activated receptor activity regulation of gene expression regulation of long-term neuronal synaptic plasticity regulation of multicellular organism growth regulation of peptidyl-tyrosine phosphorylation regulation of presynapse assembly regulation of spontaneous synaptic transmission regulation of synapse structure or activity regulation of translation response to interleukin-1 response to oxidative stress serine-type endopeptidase inhibitor activity signaling receptor activator activity signaling receptor binding smooth endoplasmic reticulum smooth endoplasmic reticulum calcium ion homeostasis spindle midzone suckling behavior synapse synapse organization synaptic assembly at neuromuscular junction synaptic vesicle trans-Golgi network membrane transition metal ion binding visual learning	GO:0000086 GO:0000978 GO:0001774 GO:0001934 GO:0001967 GO:0002265 GO:0003677 GO:0004867 GO:0005102 GO:0005576 GO:0005615 GO:0005641 GO:0005737 GO:0005768 GO:0005769 GO:0005783 GO:0005788 GO:0005790 GO:0005794 GO:0005796 GO:0005798 GO:0005829 GO:0005886 GO:0005905 GO:0005911 GO:0006378 GO:0006417 GO:0006468 GO:0006878 GO:0006897 GO:0006979 GO:0007155 GO:0007176 GO:0007219 GO:0007409 GO:0007417 GO:0007611 GO:0007612 GO:0007617 GO:0007626 GO:0008021 GO:0008088 GO:0008201 GO:0008203 GO:0008285 GO:0008344 GO:0008542 GO:0009986 GO:0010468 GO:0010628 GO:0010629 GO:0010800 GO:0010971 GO:0014005 GO:0016020 GO:0016199 GO:0016322 GO:0016358 GO:0019899 GO:0030111 GO:0030134 GO:0030198 GO:0030424 GO:0030426 GO:0030546 GO:0030900 GO:0031093 GO:0031175 GO:0031594 GO:0031904 GO:0032092 GO:0032588 GO:0032722 GO:0032731 GO:0032755 GO:0032760 GO:0033138 GO:0035235 GO:0035253 GO:0040014 GO:0042802 GO:0043197 GO:0043198 GO:0043204 GO:0043235 GO:0045121 GO:0045177 GO:0045202 GO:0045665 GO:0045821 GO:0045931 GO:0045944 GO:0046330 GO:0046914 GO:0048018 GO:0048143 GO:0048169 GO:0048471 GO:0048669 GO:0048786 GO:0050729 GO:0050730 GO:0050803 GO:0050808 GO:0050885 GO:0050890 GO:0051091 GO:0051124 GO:0051233 GO:0051247 GO:0051402 GO:0051425 GO:0051563 GO:0055037 GO:0070050 GO:0070062 GO:0070374 GO:0070555 GO:0098815 GO:0150003 GO:0180011 GO:1900272 GO:1900273 GO:1901224 GO:1904646 GO:1905606 GO:1905908 GO:1990000 GO:1990535 GO:2000310 GO:2000406
Ankyrin repeat and KH domain-containing protein 1	Q8IWZ3	ANKHD1	KIAA1085 MASK VBARP	ANKHD1 KIAA1085 MASK VBARP	Homo sapiens	9606	29	2	RNA binding cytoplasm innate immune response	GO:0003723 GO:0005737 GO:0045087
Envelope glycoprotein gp160	Q9QSQ7	env		env	HIV-1 M:F1_VI850	388813	29		clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Envelope glycoprotein gp160	Q9IDV2	env		env	HIV-1 N_YBF106	388819	29		clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Envelope glycoprotein gp160	P15831	env		env	Human immunodeficiency virus type 2 (ISOLATE D205,7)	11716	28		clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane host cell endosome membrane host cell plasma membrane membrane structural molecule activity suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway viral envelope virion attachment to host cell virion membrane	GO:0005198 GO:0016020 GO:0019031 GO:0019062 GO:0020002 GO:0039502 GO:0039587 GO:0039654 GO:0044175 GO:0055036 GO:0075512
Cadherin EGF LAG seven-pass G-type receptor 1	O35161	Celsr1		Celsr1	Mus musculus	10090	28	1	G protein-coupled receptor activity Rho protein signal transduction anterior/posterior pattern specification apical protein localization calcium ion binding cell-cell adhesion establishment of body hair planar orientation establishment of planar polarity establishment of planar polarity of embryonic epithelium hair follicle development homophilic cell adhesion via plasma membrane adhesion molecules inner ear morphogenesis lateral sprouting involved in lung morphogenesis locomotory behavior membrane motor neuron migration neural tube closure nucleoplasm orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis planar cell polarity pathway involved in neural tube closure planar dichotomous subdivision of terminal units involved in lung branching morphogenesis plasma membrane protein localization involved in establishment of planar polarity regulation of actin cytoskeleton organization wound healing	GO:0001736 GO:0001843 GO:0001942 GO:0004930 GO:0005509 GO:0005654 GO:0005886 GO:0007156 GO:0007266 GO:0007626 GO:0009952 GO:0016020 GO:0032956 GO:0042060 GO:0042249 GO:0042472 GO:0045176 GO:0048105 GO:0060488 GO:0060489 GO:0060490 GO:0090179 GO:0090251 GO:0097475 GO:0098609
Nuclear factor related to kappa-B-binding protein	Q6PIJ4	Nfrkb		Nfrkb	Mus musculus	10090	28	1	DNA binding DNA recombination DNA repair Ino80 complex chromatin remodeling nucleoplasm nucleus positive regulation of DNA repair positive regulation of DNA-templated transcription positive regulation of telomere maintenance in response to DNA damage protease binding regulation of DNA repair regulation of DNA replication regulation of DNA strand elongation regulation of cell cycle regulation of chromosome organization regulation of embryonic development telomere maintenance	GO:0000723 GO:0002020 GO:0003677 GO:0005634 GO:0005654 GO:0006275 GO:0006281 GO:0006282 GO:0006310 GO:0006338 GO:0031011 GO:0033044 GO:0045739 GO:0045893 GO:0045995 GO:0051726 GO:0060382 GO:1904507
Armadillo-like helical domain-containing protein 4	Q86TY3	ARMH4	C14orf37	ARMH4 C14orf37	Homo sapiens	9606	28	4	TORC2 complex binding membrane regulation of TORC2 signaling regulation of inflammatory response	GO:0016020 GO:0050727 GO:1903939 GO:1904841