GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID Gene Symbol Gene Symbol Aliases ▲ Gene Symbol All Species Taxonomy ID No. of Glycosylation Sites No. of GlyTouCan IDs MCAW IDs Disease Name Aliases Disease Name GO Labels GO IDs
  • HLA-C
  • HLA-C
9606
1
  • GPC
  • GPC
3052310
11
  • fusion of virus membrane with host endosome membrane
  • host cell Golgi membrane
  • host cell endoplasmic reticulum membrane
  • host cell plasma membrane
  • membrane
  • metal ion binding
  • receptor-mediated endocytosis of virus by host cell
  • viral envelope
  • virion attachment to host cell
  • virion membrane
  • GO:0016020
  • GO:0019031
  • GO:0019062
  • GO:0019065
  • GO:0020002
  • GO:0039654
  • GO:0044167
  • GO:0044178
  • GO:0046872
  • GO:0055036
  • PHYPO_G00219820
  • PHYPO_G00219820
310915
1
  • ATP binding
  • extracellularly ATP-gated monoatomic cation channel activity
  • plasma membrane
  • postsynapse
  • purinergic nucleotide receptor activity
  • response to ATP
  • GO:0001614
  • GO:0004931
  • GO:0005524
  • GO:0005886
  • GO:0033198
  • GO:0098794
  • ENPEP
  • ENPEP
9606
21
13
  • aminopeptidase activity
  • angiogenesis
  • angiotensin maturation
  • apical part of cell
  • apical plasma membrane
  • brush border
  • cell migration
  • cell population proliferation
  • cell-cell signaling
  • cytoplasm
  • cytoplasmic vesicle
  • external side of plasma membrane
  • extracellular exosome
  • glomerulus development
  • lysosomal membrane
  • metalloaminopeptidase activity
  • peptide binding
  • peptide catabolic process
  • plasma membrane
  • proteolysis
  • regulation of blood pressure
  • regulation of systemic arterial blood pressure by renin-angiotensin
  • zinc ion binding
  • GO:0001525
  • GO:0002003
  • GO:0003081
  • GO:0004177
  • GO:0005737
  • GO:0005765
  • GO:0005886
  • GO:0005903
  • GO:0006508
  • GO:0007267
  • GO:0008217
  • GO:0008270
  • GO:0008283
  • GO:0009897
  • GO:0016324
  • GO:0016477
  • GO:0031410
  • GO:0032835
  • GO:0042277
  • GO:0043171
  • GO:0045177
  • GO:0070006
  • GO:0070062
  • Nfam1
  • Nfam1
10090
1
  • membrane
  • positive regulation of B cell receptor signaling pathway
  • positive regulation of cytokine production
  • regulation of B cell differentiation
  • transmembrane signaling receptor activity
  • GO:0001819
  • GO:0004888
  • GO:0016020
  • GO:0045577
  • GO:0050861
  • bglN
  • bglN
227321
6
  • beta-glucosidase activity
  • cellulose catabolic process
  • extracellular region
  • glucan catabolic process
  • scopolin beta-glucosidase activity
  • GO:0005576
  • GO:0008422
  • GO:0009251
  • GO:0030245
  • GO:0102483
  • HLA-B
  • HLA-B
9606
1
  • ER to Golgi transport vesicle membrane
  • antigen processing and presentation
  • cell surface
  • early endosome membrane
  • immune response
  • lumenal side of endoplasmic reticulum membrane
  • phagocytic vesicle membrane
  • plasma membrane
  • recycling endosome membrane
  • GO:0005886
  • GO:0006955
  • GO:0009986
  • GO:0012507
  • GO:0019882
  • GO:0030670
  • GO:0031901
  • GO:0055038
  • GO:0098553
  • LOC118309871
  • LOC118309871
52904
2
  • G protein-coupled receptor activity
  • membrane
  • metal ion binding
  • photoreceptor activity
  • phototransduction
  • visual perception
  • GO:0004930
  • GO:0007601
  • GO:0007602
  • GO:0009881
  • GO:0016020
  • GO:0046872
  • HLA-C
  • HLA-C
9606
1
  • Ctsd
  • Ctsd
230844
2
  • aspartic-type endopeptidase activity
  • extracellular space
  • lysosome
  • proteolysis
  • GO:0004190
  • GO:0005615
  • GO:0005764
  • GO:0006508
Displaying entries 31 - 40 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01