GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs ▲	GO Labels	GO IDs
Proteasome subunit alpha type	K2MUS2	MOQ_005330		MOQ_005330	Trypanosoma cruzi marinkellei	85056		1	cytoplasm nucleus proteasome core complex, alpha-subunit complex ubiquitin-dependent protein catabolic process	GO:0005634 GO:0005737 GO:0006511 GO:0019773
Eukaryotic translation initiation factor 1	P41567	EIF1	SUI1	EIF1 SUI1	Homo sapiens	9606		1	RNA binding cytoplasm dosage compensation by inactivation of X chromosome eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex multi-eIF complex nucleus regulation of translational initiation ribosomal small subunit binding translation factor activity, RNA binding translation initiation factor activity translational initiation	GO:0003723 GO:0003743 GO:0005634 GO:0005737 GO:0006413 GO:0006446 GO:0008135 GO:0009048 GO:0016282 GO:0033290 GO:0043024 GO:0043614
NEDD8-activating enzyme E1 catalytic subunit	Q8C878	Uba3	Ube1c	Uba3 Ube1c	Mus musculus	10090		1	ATP binding NEDD8 activating enzyme activity cytoplasm endomitotic cell cycle identical protein binding mitotic cell cycle negative regulation of DNA-templated transcription nuclear receptor binding nucleus protein heterodimerization activity protein neddylation protein-containing complex protein-containing complex binding regulation of cell cycle	GO:0000278 GO:0005524 GO:0005634 GO:0005737 GO:0007113 GO:0016922 GO:0019781 GO:0032991 GO:0042802 GO:0044877 GO:0045116 GO:0045892 GO:0046982 GO:0051726
Heat shock protein beta-1	P42930	Hspb1	Hsp27	Hspb1 Hsp27	Rattus norvegicus	10116	1	1	I band M band RNA polymerase II-specific DNA-binding transcription factor binding Z disc anterograde axonal protein transport axon axon cytoplasm cardiac myofibril cellular response to butyrate cellular response to hydrogen peroxide cellular response to interleukin-11 cellular response to vascular endothelial growth factor stimulus chaperone-mediated protein folding contractile fiber cornified envelope cytoplasm dendrite female pregnancy identical protein binding intracellular signal transduction negative regulation of apoptotic process negative regulation of apoptotic signaling pathway negative regulation of cellular response to oxidative stress negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway negative regulation of regulatory T cell differentiation nucleus perikaryon plasma membrane positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of endothelial cell chemotaxis positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway positive regulation of interleukin-1 beta production positive regulation of neuron projection development positive regulation of tumor necrosis factor production postsynaptic density membrane proteasome complex protein folding chaperone protein homodimerization activity protein kinase C binding protein kinase C inhibitor activity protein kinase binding protein refolding regulation of canonical NF-kappaB signal transduction regulation of protein phosphorylation response to angiotensin response to heat response to ischemia response to muscle stretch response to virus spindle ubiquitin binding unfolded protein binding	GO:0000502 GO:0001533 GO:0001932 GO:0002931 GO:0005080 GO:0005634 GO:0005737 GO:0005819 GO:0005886 GO:0007565 GO:0008426 GO:0009408 GO:0009615 GO:0010976 GO:0019901 GO:0030018 GO:0030424 GO:0030425 GO:0031430 GO:0031674 GO:0032731 GO:0032760 GO:0035556 GO:0035924 GO:0035994 GO:0038033 GO:0042026 GO:0042802 GO:0042803 GO:0043066 GO:0043122 GO:0043130 GO:0043204 GO:0043292 GO:0043536 GO:0044183 GO:0045590 GO:0045766 GO:0051082 GO:0061077 GO:0061629 GO:0070301 GO:0071348 GO:0097512 GO:0098839 GO:0099641 GO:1900408 GO:1902176 GO:1903545 GO:1904115 GO:1990776 GO:2001028 GO:2001234
Gb\|AAF16663.1	Q9FIA3	At5g55040		At5g55040	Arabidopsis thaliana	3702		1
ATP synthase subunit beta, mitochondrial	P06576	ATP5F1B	ATP5B ATPMB ATPSB	ATP5F1B ATP5B ATPMB ATPSB	Homo sapiens	9606	2	1	ATP binding ATP biosynthetic process ATP hydrolysis activity MHC class I protein binding angiogenesis angiostatin binding cell surface cellular response to interleukin-7 extracellular exosome generation of precursor metabolites and energy lipid metabolic process membrane mitochondrial inner membrane mitochondrial matrix mitochondrial membrane mitochondrial nucleoid mitochondrial proton-transporting ATP synthase complex mitochondrial proton-transporting ATP synthase, catalytic core mitochondrion negative regulation of cell adhesion involved in substrate-bound cell migration nucleus osteoblast differentiation plasma membrane positive regulation of blood vessel endothelial cell migration proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis proton transmembrane transport proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATP synthase complex proton-transporting ATP synthase complex, catalytic core F(1) proton-transporting ATPase activity, rotational mechanism regulation of intracellular pH	GO:0001525 GO:0001649 GO:0005524 GO:0005634 GO:0005739 GO:0005743 GO:0005753 GO:0005754 GO:0005759 GO:0005886 GO:0006091 GO:0006629 GO:0006754 GO:0006933 GO:0009986 GO:0015986 GO:0016020 GO:0016887 GO:0031966 GO:0042288 GO:0042645 GO:0042776 GO:0043532 GO:0043536 GO:0045259 GO:0045261 GO:0046933 GO:0046961 GO:0051453 GO:0070062 GO:0098761 GO:1902600
Proteasome subunit beta type-7	Q99436	PSMB7	Z	PSMB7 Z	Homo sapiens	9606		1	cytoplasm cytosol endopeptidase activity extracellular region ficolin-1-rich granule lumen nuclear body nucleoplasm nucleus proteasomal protein catabolic process proteasome complex proteasome core complex proteasome core complex, beta-subunit complex proteasome-mediated ubiquitin-dependent protein catabolic process secretory granule lumen threonine-type endopeptidase activity	GO:0000502 GO:0004175 GO:0004298 GO:0005576 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005839 GO:0010498 GO:0016604 GO:0019774 GO:0034774 GO:0043161 GO:1904813
Transcriptional adapter 3	O75528	TADA3	ADA3 TADA3L	TADA3 ADA3 TADA3L	Homo sapiens	9606		1	ATAC complex SAGA complex chromatin organization intracellular estrogen receptor signaling pathway mitotic cell cycle mitotic spindle negative regulation of transcription by RNA polymerase II nuclear receptor binding nuclear receptor coactivator activity nucleoplasm nucleus positive regulation of DNA-templated transcription positive regulation of gene expression protein domain specific binding regulation of DNA repair regulation of DNA-templated transcription regulation of RNA splicing regulation of cell cycle regulation of cell division regulation of embryonic development regulation of protein phosphorylation regulation of protein stability regulation of transcription by RNA polymerase II regulation of tubulin deacetylation transcription coactivator activity transcription factor TFTC complex	GO:0000122 GO:0000124 GO:0000278 GO:0001932 GO:0003713 GO:0005634 GO:0005654 GO:0006282 GO:0006325 GO:0006355 GO:0006357 GO:0010628 GO:0016922 GO:0019904 GO:0030374 GO:0030520 GO:0031647 GO:0033276 GO:0043484 GO:0045893 GO:0045995 GO:0051302 GO:0051726 GO:0072686 GO:0090043 GO:0140672
Transcription initiation factor TFIID subunit 9	Q8VI33	Taf9	Taf2g	Taf9 Taf2g	Mus musculus	10090	3	1	ATPase binding C2H2 zinc finger domain binding DNA binding DNA-binding transcription factor binding MLL1 complex RNA polymerase II preinitiation complex assembly SAGA complex box C/D snoRNP assembly chromatin remodeling mRNA transcription by RNA polymerase II negative regulation of apoptotic process negative regulation of proteasomal ubiquitin-dependent protein catabolic process nucleoplasm nucleus p53 binding positive regulation of DNA-templated transcription positive regulation of response to cytokine stimulus positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II pre-snoRNP complex protein heterodimerization activity protein stabilization regulation of DNA repair regulation of DNA-templated transcription regulation of RNA splicing regulation of transcription by RNA polymerase II response to interleukin-1 transcription cis-regulatory region binding transcription coactivator activity transcription factor TFIID complex transcription factor TFTC complex	GO:0000124 GO:0000492 GO:0000976 GO:0002039 GO:0003677 GO:0003713 GO:0005634 GO:0005654 GO:0005669 GO:0006282 GO:0006338 GO:0006355 GO:0006357 GO:0032435 GO:0033276 GO:0042789 GO:0043066 GO:0043484 GO:0045893 GO:0045944 GO:0046982 GO:0050821 GO:0051117 GO:0051123 GO:0060261 GO:0060760 GO:0070555 GO:0070742 GO:0070761 GO:0071339 GO:0140297
AT4g26650/T15N24_100	Q8W569	At4g26650		At4g26650	Arabidopsis thaliana	3702		1	mRNA binding	GO:0003729