GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Lymphocyte antigen 86	O95711	LY86	Homo sapiens	9606	2	extracellular space inflammatory response innate immune response lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway	GO:0005615 GO:0006954 GO:0031663 GO:0031666 GO:0045087
Sushi domain-containing protein 4	Q8BH32	Susd4	Mus musculus	10090	3	membrane negative regulation of complement activation, alternative pathway negative regulation of complement activation, classical pathway regulation of complement activation	GO:0016020 GO:0030449 GO:0045957 GO:0045959
Thrombospondin-2	Q03350	Thbs2	Mus musculus	10090	7	basement membrane calcium ion binding cell adhesion collagen-containing extracellular matrix extracellular matrix extracellular region heparin binding negative regulation of angiogenesis platelet alpha granule positive regulation of synapse assembly	GO:0005509 GO:0005576 GO:0005604 GO:0007155 GO:0008201 GO:0016525 GO:0031012 GO:0031091 GO:0051965 GO:0062023
Secretogranin-3	P47867	Scg3	Mus musculus	10090	2	extracellular region protein localization to secretory granule secretory granule membrane transport vesicle membrane	GO:0005576 GO:0030658 GO:0030667 GO:0033366
Polypeptide N-acetylgalactosaminyltransferase 17	Q7TT15	Galnt17	Mus musculus	10090	3	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
B-cell antigen receptor complex-associated protein alpha chain	P11912	CD79A	Homo sapiens	9606	9	B cell activation B cell differentiation B cell proliferation B cell receptor complex B cell receptor signaling pathway adaptive immune response external side of plasma membrane identical protein binding membrane raft multivesicular body plasma membrane transmembrane signaling receptor activity	GO:0002250 GO:0004888 GO:0005771 GO:0005886 GO:0009897 GO:0019815 GO:0030183 GO:0042100 GO:0042113 GO:0042802 GO:0045121 GO:0050853
Semaphorin-4G	Q9NTN9	SEMA4G	Homo sapiens	9606	6	axon guidance chemorepellent activity negative chemotaxis negative regulation of axon extension involved in axon guidance neural crest cell migration plasma membrane positive regulation of cell migration semaphorin receptor binding semaphorin-plexin signaling pathway	GO:0001755 GO:0005886 GO:0007411 GO:0030215 GO:0030335 GO:0045499 GO:0048843 GO:0050919 GO:0071526
Leucine-rich repeat-containing protein 26	Q2I0M4	LRRC26	Homo sapiens	9606	1	cytoplasm cytoskeleton extracellular exosome plasma membrane positive regulation of voltage-gated potassium channel activity potassium channel activator activity potassium channel regulator activity potassium ion transmembrane transport transmembrane transporter binding voltage-gated potassium channel activity voltage-gated potassium channel complex	GO:0005249 GO:0005737 GO:0005856 GO:0005886 GO:0008076 GO:0015459 GO:0044325 GO:0070062 GO:0071805 GO:0099104 GO:1903818
Fc receptor-like S, scavenger receptor	Q9EQY5	Fcrl2	Mus musculus	10090	1	cell surface cell surface receptor signaling pathway membrane protein phosphatase binding signaling adaptor activity transmembrane signaling receptor activity	GO:0004888 GO:0007166 GO:0009986 GO:0016020 GO:0019903 GO:0035591
Serine/threonine-protein kinase receptor R3	Q61288	Acvrl1	Mus musculus	10090	2	ATP binding BMP receptor activity BMP receptor complex BMP signaling pathway SMAD binding activin binding activin receptor activity, type I angiogenesis artery development blood circulation blood vessel morphogenesis blood vessel remodeling cell surface cellular response to BMP stimulus cellular response to growth factor stimulus cellular response to transforming growth factor beta stimulus dendrite dorsal aorta morphogenesis dorsal/ventral pattern formation endocardial cushion morphogenesis endothelial cell activation endothelial tube morphogenesis heart development in utero embryonic development lymphangiogenesis lymphatic endothelial cell differentiation metal ion binding negative regulation of DNA biosynthetic process negative regulation of blood vessel endothelial cell migration negative regulation of cell adhesion negative regulation of cell growth negative regulation of cell migration negative regulation of cell population proliferation negative regulation of endothelial cell differentiation negative regulation of endothelial cell migration negative regulation of endothelial cell proliferation negative regulation of focal adhesion assembly negative regulation of gene expression neuronal cell body phosphorylation plasma membrane positive regulation of BMP signaling pathway positive regulation of DNA-templated transcription positive regulation of angiogenesis positive regulation of endothelial cell differentiation positive regulation of endothelial cell proliferation positive regulation of transcription by RNA polymerase II protein kinase binding protein serine/threonine kinase activity regulation of DNA-templated transcription regulation of blood pressure response to hypoxia retina vasculature development in camera-type eye signal transduction transforming growth factor beta binding transforming growth factor beta receptor activity transforming growth factor beta receptor activity, type I transforming growth factor beta receptor signaling pathway venous blood vessel development wound healing, spreading of epidermal cells	GO:0001525 GO:0001666 GO:0001701 GO:0001937 GO:0001938 GO:0001946 GO:0001974 GO:0003203 GO:0004674 GO:0005024 GO:0005025 GO:0005524 GO:0005886 GO:0006355 GO:0007162 GO:0007165 GO:0007179 GO:0007507 GO:0008015 GO:0008217 GO:0008285 GO:0009953 GO:0009986 GO:0010596 GO:0010629 GO:0016310 GO:0016361 GO:0019901 GO:0030308 GO:0030336 GO:0030425 GO:0030509 GO:0030513 GO:0035313 GO:0035912 GO:0042118 GO:0043025 GO:0043537 GO:0045602 GO:0045603 GO:0045766 GO:0045893 GO:0045944 GO:0046332 GO:0046872 GO:0048185 GO:0048514 GO:0050431 GO:0051895 GO:0060836 GO:0060840 GO:0060841 GO:0061154 GO:0061298 GO:0070724 GO:0071363 GO:0071560 GO:0071773 GO:0098821 GO:2000279