GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
GTPase-activating protein BEM2/IPL2	P39960	BEM2	Saccharomyces cerevisiae S288C	559292	46	GTPase activator activity actin cytoskeleton organization cell cortex cellular bud tip cytoplasm guanyl-nucleotide exchange factor activity incipient cellular bud site mRNA binding mating projection tip mitochondrion mitotic morphogenesis checkpoint signaling negative regulation of Rho protein signal transduction plasma membrane prospore membrane small GTPase mediated signal transduction	GO:0000131 GO:0003729 GO:0005085 GO:0005096 GO:0005628 GO:0005737 GO:0005739 GO:0005886 GO:0005934 GO:0005938 GO:0007264 GO:0030036 GO:0035024 GO:0043332 GO:0044879
Low-density lipoprotein receptor-related protein 1B	Q9NZR2	LRP1B	Homo sapiens	9606	46	calcium ion binding low-density lipoprotein particle receptor activity plasma membrane protein transport receptor complex receptor-mediated endocytosis	GO:0005041 GO:0005509 GO:0005886 GO:0006898 GO:0015031 GO:0043235
Cadherin-3	P34616	cdh-3	Caenorhabditis elegans	6239	46	anchoring junction basement membrane basement membrane disassembly basolateral plasma membrane calcium ion binding cell adhesion cytoplasm homophilic cell adhesion via plasma membrane adhesion molecules morphogenesis of embryonic epithelium nematode male tail tip morphogenesis plasma membrane structural molecule activity	GO:0005198 GO:0005509 GO:0005604 GO:0005737 GO:0005886 GO:0007155 GO:0007156 GO:0016323 GO:0016331 GO:0034769 GO:0045138 GO:0070161
Myosin-6	P02563	Myh6	Rattus norvegicus	10116	46	ATP binding ATP metabolic process Z disc actin filament binding actin filament-based movement adult heart development atrial cardiac muscle tissue morphogenesis calcium-dependent ATPase activity calmodulin binding cardiac muscle cell development cardiac muscle contraction cardiac muscle hypertrophy in response to stress cellular response to 3,3',5-triiodo-L-thyronine cytoplasm identical protein binding in utero embryonic development microfilament motor activity muscle contraction muscle filament sliding muscle myosin complex myofibril myofibril assembly myosin II complex myosin complex myosin filament protein kinase binding protein-containing complex binding regulation of blood pressure regulation of heart contraction regulation of heart growth regulation of heart rate regulation of the force of heart contraction sarcomere organization stress fiber striated muscle contraction ventricular cardiac muscle tissue morphogenesis visceral muscle development	GO:0000146 GO:0001701 GO:0001725 GO:0002026 GO:0002027 GO:0005516 GO:0005524 GO:0005737 GO:0005859 GO:0006936 GO:0006941 GO:0007512 GO:0007522 GO:0008016 GO:0008217 GO:0014898 GO:0016459 GO:0016460 GO:0019901 GO:0030016 GO:0030018 GO:0030048 GO:0030049 GO:0030239 GO:0030899 GO:0032982 GO:0042802 GO:0044877 GO:0045214 GO:0046034 GO:0051015 GO:0055009 GO:0055010 GO:0055013 GO:0060048 GO:0060420 GO:1905243
Colossin-B	Q8T2A1	colB	Dictyostelium discoideum	44689	45	extracellular region spore wall sporulation resulting in formation of a cellular spore	GO:0005576 GO:0030435 GO:0031160
Platelet glycoprotein Ib alpha chain	P07359	GP1BA	Homo sapiens	9606	45	blood coagulation blood coagulation, intrinsic pathway cell adhesion cell morphogenesis cell surface cell surface receptor signaling pathway external side of plasma membrane extracellular exosome extracellular matrix extracellular space fibrinolysis glycoprotein Ib-IX-V complex megakaryocyte development membrane plasma membrane platelet activation positive regulation of leukocyte tethering or rolling positive regulation of platelet activation regulation of blood coagulation release of sequestered calcium ion into cytosol thrombin-activated receptor activity	GO:0000902 GO:0005615 GO:0005886 GO:0007155 GO:0007166 GO:0007596 GO:0007597 GO:0009897 GO:0009986 GO:0010572 GO:0015057 GO:0016020 GO:0030168 GO:0030193 GO:0031012 GO:0035855 GO:0042730 GO:0051209 GO:0070062 GO:1903238 GO:1990779
Serine/arginine repetitive matrix protein 2	Q9UQ35	SRRM2	Homo sapiens	9606	45	C2H2 zinc finger domain binding Cajal body RNA binding U2-type catalytic step 2 spliceosome U2-type precatalytic spliceosome catalytic step 2 spliceosome mRNA binding mRNA splicing, via spliceosome nuclear speck nucleoplasm nucleus	GO:0000398 GO:0003723 GO:0003729 GO:0005634 GO:0005654 GO:0015030 GO:0016607 GO:0070742 GO:0071005 GO:0071007 GO:0071013
Tenascin-X	P22105	TNXB	Homo sapiens	9606	44	actin cytoskeleton organization cell adhesion cell-cell adhesion cell-matrix adhesion collagen binding collagen fibril binding collagen fibril organization collagen metabolic process collagen-containing extracellular matrix elastic fiber assembly extracellular exosome extracellular matrix extracellular matrix structural constituent extracellular region extracellular space fatty acid metabolic process heparin binding integrin binding intracellular membrane-bounded organelle neuron projection development positive regulation of cell fate determination positive regulation of cell population proliferation positive regulation of collagen fibril organization positive regulation of epithelial to mesenchymal transition positive regulation of transforming growth factor beta activation positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of vascular endothelial growth factor signaling pathway regulation of cell adhesion regulation of cell differentiation regulation of cell migration tenascin complex triglyceride metabolic process	GO:0005178 GO:0005201 GO:0005518 GO:0005576 GO:0005615 GO:0006631 GO:0006641 GO:0007155 GO:0007160 GO:0008201 GO:0008284 GO:0010718 GO:0030036 GO:0030155 GO:0030199 GO:0030334 GO:0030511 GO:0031012 GO:0031175 GO:0032963 GO:0043231 GO:0045595 GO:0048251 GO:0062023 GO:0070062 GO:0090733 GO:0098609 GO:0098633 GO:1900748 GO:1901390 GO:1904028 GO:1905935
Non-classical arabinogalactan protein 31	Q9FZA2	AGP31	Arabidopsis thaliana	3702	44	extracellular region plant-type cell wall plasma membrane plasmodesma response to jasmonic acid	GO:0005576 GO:0005886 GO:0009505 GO:0009506 GO:0009753
Gametocyte surface protein P230	P68875	PF230	Plasmodium falciparum NF54	5843	44	cell surface plasma membrane	GO:0005886 GO:0009986