GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name ▼ UniProt ID Gene Symbol Species Taxonomy ID No. of Glycosylation Sites GO Labels GO IDs
  • TRM732
559292
2
  • cytoplasm
  • tRNA methylation
  • tRNA nucleoside ribose methylation
  • wobble position ribose methylation
  • GO:0002128
  • GO:0002130
  • GO:0005737
  • GO:0030488
  • THADA
9606
1
  • adaptive thermogenesis
  • cytoplasmic side of endoplasmic reticulum membrane
  • enzyme regulator activity
  • lipid homeostasis
  • negative regulation of endoplasmic reticulum calcium ion concentration
  • tRNA methylation
  • tRNA nucleoside ribose methylation
  • GO:0002128
  • GO:0030234
  • GO:0030488
  • GO:0032471
  • GO:0055088
  • GO:0098554
  • GO:1990845
  • SNAPC4
9606
  • DNA binding
  • RNA polymerase II general transcription initiation factor activity
  • RNA polymerase III general transcription initiation factor activity
  • RNA polymerase III type 3 promoter sequence-specific DNA binding
  • nucleoplasm
  • nucleus
  • snRNA transcription by RNA polymerase II
  • snRNA transcription by RNA polymerase III
  • snRNA-activating protein complex
  • GO:0000995
  • GO:0001006
  • GO:0003677
  • GO:0005634
  • GO:0005654
  • GO:0016251
  • GO:0019185
  • GO:0042795
  • GO:0042796
  • SNAPC1
9606
1
  • RNA polymerase II general transcription initiation factor activity
  • RNA polymerase III general transcription initiation factor activity
  • nucleolus
  • nucleoplasm
  • sequence-specific DNA binding
  • snRNA transcription by RNA polymerase II
  • snRNA transcription by RNA polymerase III
  • snRNA-activating protein complex
  • GO:0000995
  • GO:0005654
  • GO:0005730
  • GO:0016251
  • GO:0019185
  • GO:0042795
  • GO:0042796
  • GO:0043565
  • HE
237020
6
  • fusion of virus membrane with host plasma membrane
  • host cell plasma membrane
  • host cell surface receptor binding
  • plasma membrane
  • sialate 4-O-acetylesterase activity
  • sialate 9-O-acetylesterase activity
  • viral envelope
  • GO:0005886
  • GO:0019031
  • GO:0019064
  • GO:0020002
  • GO:0046789
  • GO:0106330
  • GO:0106331
  • TCDM_00585
1416333
  • ATP binding
  • serine-tRNA ligase activity
  • seryl-tRNA aminoacylation
  • GO:0004828
  • GO:0005524
  • GO:0006434
  • Sars1
10090
  • ATP binding
  • RNA polymerase II cis-regulatory region sequence-specific DNA binding
  • cytoplasmic translation
  • cytosol
  • enzyme binding
  • molecular adaptor activity
  • negative regulation of angiogenesis
  • negative regulation of transcription by RNA polymerase II
  • negative regulation of vascular endothelial growth factor production
  • nucleus
  • protein homodimerization activity
  • selenocysteine incorporation
  • selenocysteine-tRNA ligase activity
  • serine-tRNA ligase activity
  • seryl-tRNA aminoacylation
  • tRNA modification
  • GO:0000122
  • GO:0000978
  • GO:0001514
  • GO:0002181
  • GO:0004828
  • GO:0005524
  • GO:0005634
  • GO:0005829
  • GO:0006400
  • GO:0006434
  • GO:0016525
  • GO:0019899
  • GO:0042803
  • GO:0060090
  • GO:0098619
  • GO:1904046
  • ACTIB-I
5061
2
  • RNA binding
  • organic substance metabolic process
  • ribonuclease T2 activity
  • GO:0003723
  • GO:0033897
  • GO:0071704
  • TGVEG_268590
432359
  • membrane
  • proteolysis
  • serine-type endopeptidase activity
  • GO:0004252
  • GO:0006508
  • GO:0016020
  • Fgfr2
159581
8
  • ATP binding
  • fibroblast growth factor receptor activity
  • plasma membrane
  • positive regulation of cell population proliferation
  • GO:0005007
  • GO:0005524
  • GO:0005886
  • GO:0008284
Displaying entries 101 - 110 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01