GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Cubilin	F1RWC3	CUBN	Sus scrofa	9823	44	apical plasma membrane calcium ion binding cholesterol metabolic process clathrin-coated pit cobalamin binding endosome extracellular space lysosomal membrane protein transport serine-type endopeptidase activity	GO:0004252 GO:0005509 GO:0005615 GO:0005765 GO:0005768 GO:0005905 GO:0008203 GO:0015031 GO:0016324 GO:0031419
Mucin-5B	Q9HC84	MUC5B	Homo sapiens	9606	44	Golgi lumen extracellular exosome extracellular matrix extracellular space intracellular membrane-bounded organelle metal ion binding plasma membrane	GO:0005615 GO:0005796 GO:0005886 GO:0031012 GO:0043231 GO:0046872 GO:0070062
Cubilin	Q9TU53	CUBN	Canis lupus familiaris	9615	44	apical plasma membrane brush border membrane calcium ion binding cholesterol metabolic process clathrin-coated pit cobalamin binding endosome lysosomal membrane protein transport receptor complex	GO:0005509 GO:0005765 GO:0005768 GO:0005905 GO:0008203 GO:0015031 GO:0016324 GO:0031419 GO:0031526 GO:0043235
SCO-spondin	Q2PC93	SSPO	Gallus gallus	9031	44	cell adhesion extracellular matrix extracellular space	GO:0005615 GO:0007155 GO:0031012
SCO-spondin	Q8CG65	Sspo	Mus musculus	10090	44	cell adhesion collagen-containing extracellular matrix cytoplasm extracellular matrix extracellular space	GO:0005615 GO:0005737 GO:0007155 GO:0031012 GO:0062023
Gametocyte surface protein P230	P68874	PFS230	Plasmodium falciparum 3D7	36329	44	cell surface plasma membrane	GO:0005886 GO:0009986
Ankyrin repeat domain-containing protein 17	O75179	ANKRD17	Homo sapiens	9606	44	RNA binding blood vessel maturation chromatin chromatin binding cytoplasm defense response to bacterium innate immune response male germ cell nucleus membrane negative regulation of smooth muscle cell differentiation nuclear membrane nucleoplasm nucleus positive regulation of G1/S transition of mitotic cell cycle positive regulation of MDA-5 signaling pathway positive regulation of RIG-I signaling pathway positive regulation of canonical NF-kappaB signal transduction positive regulation of cell cycle regulation of DNA replication	GO:0000785 GO:0001673 GO:0001955 GO:0003682 GO:0003723 GO:0005634 GO:0005654 GO:0005737 GO:0006275 GO:0016020 GO:0031965 GO:0042742 GO:0043123 GO:0045087 GO:0045787 GO:0051151 GO:1900087 GO:1900245 GO:1900246
Nuclear receptor corepressor 2	Q9Y618	NCOR2	Homo sapiens	9606	43	DNA binding Notch binding cerebellum development chromatin chromatin binding estrous cycle histone deacetylase binding lactation membrane negative regulation of DNA-templated transcription negative regulation of androgen receptor signaling pathway negative regulation of miRNA transcription negative regulation of transcription by RNA polymerase II nuclear body nuclear glucocorticoid receptor binding nuclear matrix nuclear retinoid X receptor binding nucleoplasm nucleus regulation of cellular ketone metabolic process response to estradiol response to organonitrogen compound transcription corepressor activity transcription repressor complex	GO:0000122 GO:0000785 GO:0003677 GO:0003682 GO:0003714 GO:0005112 GO:0005634 GO:0005654 GO:0007595 GO:0010243 GO:0010565 GO:0016020 GO:0016363 GO:0016604 GO:0017053 GO:0021549 GO:0032355 GO:0035259 GO:0042826 GO:0044849 GO:0045892 GO:0046965 GO:0060766 GO:1902894
Serine/threonine-protein kinase WNK1	P83741	Wnk1	Mus musculus	10090	43	ATP binding GABA-ergic synapse T cell receptor signaling pathway cell volume homeostasis cellular hyperosmotic response cellular response to calcium ion cellular response to chemokine chemokine (C-C motif) ligand 21 signaling pathway cytoplasm cytosol heart development intracellular chloride ion homeostasis intracellular non-membrane-bounded organelle intracellular signal transduction lymphocyte migration into lymph node magnesium ion binding membrane mitotic spindle modulation of chemical synaptic transmission molecular condensate scaffold activity monoatomic cation homeostasis monoatomic ion homeostasis monoatomic ion transport negative regulation of GTPase activity negative regulation of autophagy negative regulation of cell-cell adhesion mediated by integrin negative regulation of heterotypic cell-cell adhesion negative regulation of leukocyte cell-cell adhesion negative regulation of pancreatic juice secretion negative regulation of protein localization to plasma membrane negative regulation of protein ubiquitination negative regulation of sodium ion transport non-membrane-bounded organelle assembly nucleus peptidyl-serine phosphorylation peptidyl-threonine phosphorylation phosphatase binding positive regulation of T cell chemotaxis positive regulation of angiogenesis positive regulation of canonical Wnt signaling pathway positive regulation of mitotic cytokinesis positive regulation of potassium ion import across plasma membrane positive regulation of systemic arterial blood pressure positive regulation of termination of RNA polymerase II transcription potassium channel inhibitor activity potassium ion homeostasis protein insertion into ER membrane by stop-transfer membrane-anchor sequence protein kinase activator activity protein kinase activity protein kinase binding protein serine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase inhibitor activity protein-containing complex regulation of blood pressure regulation of mRNA export from nucleus regulation of monoatomic cation transmembrane transport regulation of sodium ion transmembrane transport regulation of sodium ion transport signal transduction sodium ion transmembrane transport	GO:0000287 GO:0002028 GO:0003084 GO:0004672 GO:0004674 GO:0005524 GO:0005634 GO:0005737 GO:0005829 GO:0006811 GO:0006884 GO:0007165 GO:0007507 GO:0008217 GO:0010507 GO:0010766 GO:0010793 GO:0010820 GO:0016020 GO:0018105 GO:0018107 GO:0019870 GO:0019901 GO:0019902 GO:0030291 GO:0030295 GO:0030644 GO:0031397 GO:0032991 GO:0033633 GO:0034115 GO:0034260 GO:0035556 GO:0035725 GO:0038116 GO:0043232 GO:0045050 GO:0045766 GO:0050801 GO:0050804 GO:0050852 GO:0055075 GO:0055080 GO:0071277 GO:0071474 GO:0072686 GO:0090188 GO:0090263 GO:0097022 GO:0098982 GO:0106310 GO:0140693 GO:0140694 GO:1902305 GO:1903038 GO:1903077 GO:1903288 GO:1903490 GO:1904062 GO:1904595 GO:1990869
Transport and Golgi organization protein 1 homolog	Q5JRA6	MIA3	Homo sapiens	9606	43	COPII-coated vesicle cargo loading cargo receptor activity cell migration involved in sprouting angiogenesis cellular response to oxidised low-density lipoprotein particle stimulus endoplasmic reticulum exit site endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport exocytosis intracellular membrane-bounded organelle lipoprotein transport membrane negative regulation of cell adhesion negative regulation of cell migration negative regulation of leukocyte cell-cell adhesion negative regulation of lymphocyte migration positive regulation of leukocyte migration protein localization to endoplasmic reticulum exit site protein secretion protein transport vesicle cargo loading wound healing	GO:0002042 GO:0002687 GO:0005788 GO:0005789 GO:0006887 GO:0006888 GO:0007029 GO:0007162 GO:0009306 GO:0015031 GO:0016020 GO:0030336 GO:0035459 GO:0038024 GO:0042060 GO:0042953 GO:0043231 GO:0070971 GO:0070973 GO:0090110 GO:0140052 GO:1903038 GO:2000402