GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Phosphoinositide phospholipase C	A0A669BFI1	plcd1	Oreochromis niloticus	8128	1	calcium ion binding intracellular signal transduction lipid catabolic process phosphatidylinositol phospholipase C activity	GO:0004435 GO:0005509 GO:0016042 GO:0035556
Phosphoinositide phospholipase C	A0A2K5QVW9	PLCD1	Cebus imitator	2715852	2	calcium ion binding intracellular signal transduction lipid catabolic process phosphatidylinositol phospholipase C activity	GO:0004435 GO:0005509 GO:0016042 GO:0035556
AKT1 substrate 1 (proline-rich) (Fragment)	D3Z4W3	Akt1s1	Mus musculus	10090		negative regulation of TOR signaling neurotrophin TRK receptor signaling pathway	GO:0032007 GO:0048011
Xyloglucan endotransglucosylase/hydrolase	A0A1S3YUB8	LOC107779876	Nicotiana tabacum	4097	1	apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Glutamate receptor ionotropic, kainate 1	Q60934	Grik1	Mus musculus	10090	8	L-glutamate transmembrane transporter activity SNARE binding adult behavior behavioral response to pain dendrite establishment of localization in cell excitatory postsynaptic potential extracellularly glutamate-gated ion channel activity gamma-aminobutyric acid secretion glutamate binding glutamate-gated receptor activity glutamatergic synapse identical protein binding inhibitory postsynaptic potential intracellular membrane-bounded organelle ionotropic glutamate receptor complex ionotropic glutamate receptor signaling pathway kainate selective glutamate receptor activity kainate selective glutamate receptor complex ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential membrane membrane depolarization modulation of chemical synaptic transmission modulation of excitatory postsynaptic potential negative regulation of synaptic transmission, GABAergic negative regulation of synaptic transmission, glutamatergic nervous system development neuronal cell body plasma membrane positive regulation of gamma-aminobutyric acid secretion positive regulation of synaptic transmission, GABAergic postsynaptic density postsynaptic density membrane presynaptic membrane presynaptic modulation of chemical synaptic transmission receptor complex regulation of long-term neuronal synaptic plasticity regulation of membrane potential regulation of short-term neuronal synaptic plasticity scaffold protein binding synapse synaptic transmission, GABAergic synaptic transmission, glutamatergic terminal bouton transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GO:0000149 GO:0004970 GO:0005234 GO:0005313 GO:0005886 GO:0007399 GO:0008328 GO:0014051 GO:0014054 GO:0014069 GO:0015277 GO:0016020 GO:0016595 GO:0030425 GO:0030534 GO:0032229 GO:0032230 GO:0032983 GO:0035235 GO:0035249 GO:0042391 GO:0042734 GO:0042802 GO:0043025 GO:0043195 GO:0043231 GO:0043235 GO:0045202 GO:0048169 GO:0048172 GO:0048266 GO:0050804 GO:0051649 GO:0051899 GO:0051932 GO:0051967 GO:0060079 GO:0060080 GO:0097110 GO:0098815 GO:0098839 GO:0098978 GO:0099171 GO:0099507 GO:1904315
Rhodopsin	A0A2U8BND6	RH1	Lampropeltis getula	94887	2	G protein-coupled receptor activity membrane metal ion binding photoreceptor activity phototransduction visual perception	GO:0004930 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0046872
Matrix protein 2	V5QXC6	M2	Influenza A virus (A/swine/North Carolina/00371/2004(H1N1))	982621	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Actin, beta	A0A0G2K3K2	Actb	Rattus norvegicus	10116		NuA4 histone acetyltransferase complex Schaffer collateral - CA1 synapse Tat protein binding adherens junction adherens junction assembly apical junction complex apical protein localization brush border calyx of Held cell motility cellular response to cytochalasin B cortical cytoskeleton cytoplasmic ribonucleoprotein granule cytosol establishment or maintenance of cell polarity glutamatergic synapse identical protein binding kinesin binding lamellipodium morphogenesis of a polarized epithelium nitric-oxide synthase binding nucleosome nucleus positive regulation of double-strand break repair via homologous recombination postsynaptic actin cytoskeleton protein kinase binding protein localization to adherens junction regulation of cell cycle regulation of norepinephrine uptake regulation of protein localization to plasma membrane regulation of synaptic vesicle endocytosis regulation of transepithelial transport ribonucleoprotein complex structural constituent of postsynaptic actin cytoskeleton tight junction	GO:0000786 GO:0001738 GO:0005634 GO:0005829 GO:0005903 GO:0005912 GO:0007163 GO:0019894 GO:0019901 GO:0030027 GO:0030863 GO:0030957 GO:0034333 GO:0035267 GO:0036464 GO:0042802 GO:0043296 GO:0044305 GO:0045176 GO:0048870 GO:0050998 GO:0051621 GO:0051726 GO:0070160 GO:0071896 GO:0072749 GO:0098685 GO:0098871 GO:0098973 GO:0098978 GO:0150111 GO:1900242 GO:1903076 GO:1905168 GO:1990904
A disintegrin and metallopeptidase domain 10 (Fragment)	D3Z1E6	Adam10	Mus musculus	10090	1	metallopeptidase activity	GO:0008237
P2X purinoceptor	A0A8C2MMZ3	P2rx2	Cricetulus griseus	10029	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794