GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▼	No. of Glycosylation Sites	GO Labels	GO IDs
Beta-secretase 2	A0A8C2LK34	Bace2	Cricetulus griseus	10029	2	aspartic-type endopeptidase activity endosome membrane proteolysis	GO:0004190 GO:0005768 GO:0006508 GO:0016020
5-hydroxytryptamine receptor 1B	P46636	HTR1B	Cricetulus griseus	10029	2	G protein-coupled serotonin receptor activity adenylate cyclase-inhibiting serotonin receptor signaling pathway behavior bone remodeling cellular response to alkaloid cellular response to xenobiotic stimulus chemical synaptic transmission negative regulation of serotonin secretion plasma membrane presynapse presynaptic modulation of chemical synaptic transmission regulation of behavior serotonergic synapse vasoconstriction	GO:0004993 GO:0005886 GO:0007198 GO:0007268 GO:0007610 GO:0014063 GO:0042310 GO:0046849 GO:0050795 GO:0071312 GO:0071466 GO:0098793 GO:0099154 GO:0099171
Legumain	G3I1H5	Lgmn	Cricetulus griseus	10029	3	apical part of cell associative learning cellular response to amyloid-beta cellular response to calcium ion cellular response to hepatocyte growth factor stimulus cysteine-type endopeptidase activity dendritic spine organization extracellular region late endosome lysosome memory negative regulation of ERBB signaling pathway negative regulation of gene expression negative regulation of multicellular organism growth negative regulation of neuron apoptotic process perinuclear region of cytoplasm positive regulation of cell population proliferation positive regulation of endothelial cell chemotaxis positive regulation of long-term synaptic potentiation positive regulation of mitotic cell cycle positive regulation of monocyte chemotaxis proteolysis involved in protein catabolic process receptor catabolic process renal system process response to acidic pH self proteolysis	GO:0003014 GO:0004197 GO:0005576 GO:0005764 GO:0005770 GO:0007613 GO:0008284 GO:0008306 GO:0010447 GO:0010629 GO:0032801 GO:0035729 GO:0040015 GO:0043524 GO:0045177 GO:0045931 GO:0048471 GO:0051603 GO:0071277 GO:0090026 GO:0097061 GO:0097264 GO:1900273 GO:1901185 GO:1904646 GO:2001028
Hyaluronidase	A0A061IIY5	H671_1g2597	Cricetulus griseus	10029	1	carbohydrate metabolic process hyalurononglucosaminidase activity membrane	GO:0004415 GO:0005975 GO:0016020
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	A0A061IFN8	H671_3g9495	Cricetulus griseus	10029	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
P2X purinoceptor	A0A061I8N7	P2rx6	Cricetulus griseus	10029	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Beta-1,4-galactosyltransferase 2	Q80WN9	B4GALT2	Cricetulus griseus	10029	3	Golgi cisterna membrane N-acetyllactosamine synthase activity beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity carbohydrate metabolic process cerebellar Purkinje cell layer development lactose synthase activity locomotory behavior memory metal ion binding nucleoplasm visual learning	GO:0003831 GO:0003945 GO:0004461 GO:0005654 GO:0005975 GO:0007613 GO:0007626 GO:0008542 GO:0021680 GO:0032580 GO:0046872
protein adenylyltransferase	A0A8J4SQA1	PHET_04623	Paragonimus heterotremus	100268	1	ATP binding nucleotidyltransferase activity	GO:0005524 GO:0016779
Alpha-crystallin A chain	P68283	CRYAA	Pedetes capensis	10023	1	cytoplasm metal ion binding nucleus structural constituent of eye lens	GO:0005212 GO:0005634 GO:0005737 GO:0046872
C-C chemokine receptor type 5	Q9XT76	CCR5	Allochrocebus lhoesti	100224	2	C-C chemokine receptor activity chemotaxis external side of plasma membrane immune response inflammatory response	GO:0006935 GO:0006954 GO:0006955 GO:0009897 GO:0016493