GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol ▲	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Protein Wnt-11b	P49893	wnt11b	Xenopus laevis	8355	4	GTPase activator activity Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway Wnt-protein binding canonical Wnt signaling pathway cell migration involved in gastrulation collagen-containing extracellular matrix convergent extension involved in gastrulation cytoplasm dorsal/ventral axis specification endocytosis extracellular region extracellular space frizzled binding growth factor binding heart development heart formation negative regulation of DNA-templated transcription negative regulation of canonical Wnt signaling pathway negative regulation of cell growth negative regulation of cell migration neural crest cell migration neuroendocrine cell differentiation non-canonical Wnt signaling pathway plasma membrane positive regulation of DNA-templated transcription positive regulation of GTPase activity positive regulation of JNK cascade positive regulation of protein kinase C signaling positive regulation of stress fiber assembly pronephros development protein homodimerization activity protein kinase activator activity protein localization to cell surface protein phosphorylation protein-containing complex secondary palate development signal transduction	GO:0001755 GO:0005096 GO:0005109 GO:0005576 GO:0005615 GO:0005737 GO:0005886 GO:0006468 GO:0006897 GO:0007165 GO:0007507 GO:0009950 GO:0016055 GO:0017147 GO:0019838 GO:0030295 GO:0030308 GO:0030336 GO:0032991 GO:0034394 GO:0035567 GO:0042074 GO:0042803 GO:0043547 GO:0045892 GO:0045893 GO:0046330 GO:0048793 GO:0051496 GO:0060027 GO:0060070 GO:0060071 GO:0060914 GO:0061101 GO:0062009 GO:0062023 GO:0090037 GO:0090090
Protein Wnt-11b-1	Q66II0	wnt11b-1	Xenopus tropicalis	8364	4	Wnt signaling pathway extracellular region gastrulation signaling receptor binding	GO:0005102 GO:0005576 GO:0007369 GO:0016055
Protein Wnt-11b-2	Q28J82	wnt11b-2	Xenopus tropicalis	8364	4	Wnt signaling pathway extracellular region gastrulation signaling receptor binding	GO:0005102 GO:0005576 GO:0007369 GO:0016055
Protein Wnt-2	Q92048	wnt2	Danio rerio	7955	2	canonical Wnt signaling pathway cell fate commitment cell migration involved in gastrulation cytokine activity extracellular space frizzled binding hepatocyte proliferation liver development neuron differentiation swim bladder development	GO:0001889 GO:0005109 GO:0005125 GO:0005615 GO:0030182 GO:0042074 GO:0045165 GO:0048794 GO:0060070 GO:0072574
Protein Wnt-2b-A	P87387	wnt2b-a	Xenopus laevis	8355	1	Wnt signaling pathway extracellular region signaling receptor binding	GO:0005102 GO:0005576 GO:0016055
Protein Wnt-2b-B (Fragment)	P31283	wnt2b-b	Xenopus laevis	8355	1	Wnt signaling pathway extracellular region signaling receptor binding	GO:0005102 GO:0005576 GO:0016055
Protein Wnt-3 (Fragment)	P31284	wnt3	Xenopus laevis	8355	1	Wnt signaling pathway extracellular region signaling receptor binding	GO:0005102 GO:0005576 GO:0016055
Protein Wnt-3a	P31285	wnt3a	Xenopus laevis	8355	2	Wnt signaling pathway canonical Wnt signaling pathway extracellular space neural crest cell differentiation positive regulation of DNA-binding transcription factor activity signaling receptor binding	GO:0005102 GO:0005615 GO:0014033 GO:0016055 GO:0051091 GO:0060070
Protein Wnt-4	P49338	wnt4	Xenopus laevis	8355	2	Wnt signaling pathway embryonic pattern specification extracellular region glomus development nephrostome development pronephric nephron tubule development signaling receptor binding	GO:0005102 GO:0005576 GO:0009880 GO:0016055 GO:0039018 GO:0039020 GO:0072013
Protein Wnt-4a	P47793	wnt4a	Danio rerio	7955	2	canonical Wnt signaling pathway cell fate commitment cell migration involved in gastrulation cytokine activity embryonic viscerocranium morphogenesis extracellular space frizzled binding habenula development heart development neuron differentiation positive regulation of DNA-templated transcription regulation of axon extension involved in axon guidance sensory epithelium regeneration	GO:0005109 GO:0005125 GO:0005615 GO:0007507 GO:0021986 GO:0030182 GO:0042074 GO:0045165 GO:0045893 GO:0048703 GO:0048841 GO:0060070 GO:0070654