GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	GO Labels	GO IDs
Type IV secretion system protein	Q5FF32	virB11	Ehrlichia ruminantium str. Gardel	302409	ATP binding cytoplasm secretion by the type IV secretion system type IV secretion system complex	GO:0005524 GO:0005737 GO:0043684 GO:0044097
Tubulin beta-1 chain	Q9ZRB2	TUBB1	Triticum aestivum	4565	GTP binding GTPase activity cytoplasm metal ion binding microtubule microtubule cytoskeleton organization mitotic cell cycle structural constituent of cytoskeleton	GO:0000226 GO:0000278 GO:0003924 GO:0005200 GO:0005525 GO:0005737 GO:0005874 GO:0046872
Exosome RNA helicase MTR4	P42285	MTREX	Homo sapiens	9606	ATP binding ATP hydrolysis activity DNA damage response RNA binding RNA catabolic process RNA helicase activity TRAMP complex catalytic step 2 spliceosome mRNA splicing, via spliceosome maturation of 5.8S rRNA nuclear speck nucleolus nucleoplasm nucleus rRNA processing snRNA catabolic process	GO:0000398 GO:0000460 GO:0003723 GO:0003724 GO:0005524 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0006401 GO:0006974 GO:0016076 GO:0016607 GO:0016887 GO:0031499 GO:0071013
Probable eukaryotic initiation factor 4A	Q4E162	Tc00.1047053511585.190	Trypanosoma cruzi strain CL Brener	353153	ATP binding ATP hydrolysis activity RNA binding RNA helicase activity translation initiation factor activity	GO:0003723 GO:0003724 GO:0003743 GO:0005524 GO:0016887
Twist-related protein 1	Q15672	TWIST1	Homo sapiens	9606	DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity E-box binding RNA polymerase II transcription regulatory region sequence-specific DNA binding aortic valve morphogenesis bHLH transcription factor binding cardiac neural crest cell migration involved in outflow tract morphogenesis cell proliferation involved in heart valve development cellular response to growth factor stimulus cellular response to hypoxia chromatin cis-regulatory region sequence-specific DNA binding cranial suture morphogenesis developmental process embryonic camera-type eye formation embryonic cranial skeleton morphogenesis embryonic digit morphogenesis embryonic forelimb morphogenesis embryonic hindlimb morphogenesis endocardial cushion morphogenesis energy homeostasis eyelid development in camera-type eye histone deacetylase binding in utero embryonic development mitral valve morphogenesis muscle organ development negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of DNA-templated transcription negative regulation of apoptotic process negative regulation of cellular senescence negative regulation of double-strand break repair negative regulation of macrophage cytokine production negative regulation of miRNA transcription negative regulation of osteoblast differentiation negative regulation of peroxisome proliferator activated receptor signaling pathway negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of skeletal muscle tissue development negative regulation of striated muscle tissue development negative regulation of transcription by RNA polymerase II negative regulation of tumor necrosis factor production neural tube closure neuron migration nucleoplasm nucleus ossification osteoblast differentiation outer ear morphogenesis positive regulation of DNA-templated transcription initiation positive regulation of angiogenesis positive regulation of cell migration positive regulation of cell motility positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation positive regulation of epithelial cell proliferation positive regulation of epithelial to mesenchymal transition positive regulation of fatty acid beta-oxidation positive regulation of gene expression positive regulation of interleukin-6 production positive regulation of monocyte chemotactic protein-1 production positive regulation of transcription by RNA polymerase II positive regulation of transcription regulatory region DNA binding positive regulation of tumor necrosis factor production protein domain specific binding protein homodimerization activity regulation of bone mineralization regulation of transcription by RNA polymerase II rhythmic process roof of mouth development transcription coregulator binding	GO:0000122 GO:0000785 GO:0000977 GO:0000981 GO:0000987 GO:0001217 GO:0001221 GO:0001503 GO:0001649 GO:0001701 GO:0001764 GO:0001843 GO:0003180 GO:0003183 GO:0003203 GO:0003253 GO:0005634 GO:0005654 GO:0006357 GO:0007517 GO:0010628 GO:0010718 GO:0010936 GO:0019904 GO:0030335 GO:0030500 GO:0032000 GO:0032502 GO:0032720 GO:0032755 GO:0032760 GO:0035115 GO:0035116 GO:0035359 GO:0042473 GO:0042733 GO:0042803 GO:0042826 GO:0043066 GO:0043425 GO:0043518 GO:0045668 GO:0045766 GO:0045843 GO:0045892 GO:0045944 GO:0048511 GO:0048642 GO:0048701 GO:0050679 GO:0051898 GO:0060021 GO:0060363 GO:0060900 GO:0061029 GO:0070888 GO:0071363 GO:0071456 GO:0071639 GO:0097009 GO:0140297 GO:1902894 GO:2000144 GO:2000147 GO:2000679 GO:2000773 GO:2000780 GO:2000793 GO:2000802
60S ribosomal protein L26, putative	Q4DG45	Tc00.1047053510761.14	Trypanosoma cruzi strain CL Brener	353153	RNA binding large ribosomal subunit structural constituent of ribosome translation	GO:0003723 GO:0003735 GO:0006412 GO:0015934
Cystatin-A	P01040	CSTA	Homo sapiens	9606	cell-cell adhesion cornified envelope cysteine-type endopeptidase inhibitor activity cytoplasm cytosol extracellular space keratinocyte differentiation negative regulation of peptidase activity negative regulation of proteolysis nucleoplasm peptidase inhibitor complex peptide cross-linking protease binding	GO:0001533 GO:0002020 GO:0004869 GO:0005615 GO:0005654 GO:0005737 GO:0005829 GO:0010466 GO:0018149 GO:0030216 GO:0045861 GO:0098609 GO:1904090
YY1 transcription factor	K9IVK7	YY1	Sus scrofa	9823	B cell differentiation DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific Ino80 complex PcG protein complex RNA binding RNA localization RNA polymerase II cis-regulatory region sequence-specific DNA binding SMAD binding anterior/posterior pattern specification camera-type eye morphogenesis cellular response to UV chromatin binding chromatin remodeling chromatin silencing complex double-strand break repair via homologous recombination four-way junction DNA binding immunoglobulin heavy chain V-D-J recombination negative regulation of interferon-beta production negative regulation of miRNA transcription positive regulation of DNA repair positive regulation of gene expression positive regulation of telomere maintenance in response to DNA damage regulation of DNA replication regulation of DNA strand elongation regulation of cell cycle regulation of embryonic development response to UV-C spermatogenesis telomere maintenance transcription regulator complex	GO:0000400 GO:0000723 GO:0000724 GO:0000978 GO:0001227 GO:0001228 GO:0003682 GO:0003723 GO:0005667 GO:0005677 GO:0006275 GO:0006338 GO:0006403 GO:0007283 GO:0009952 GO:0010225 GO:0010628 GO:0030183 GO:0031011 GO:0031519 GO:0032688 GO:0034644 GO:0045739 GO:0045995 GO:0046332 GO:0048593 GO:0051726 GO:0060382 GO:0071707 GO:0140297 GO:1902894 GO:1904507
Ubiquitin-like protein	V5AVM2	TCDM_06868	Trypanosoma cruzi Dm28c	1416333
Saccharopine dehydrogenase-like oxidoreductase	Q8R127	Sccpdh	Mus musculus	10090	glycolipid biosynthetic process lipid droplet midbody mitochondrion oxidoreductase activity	GO:0005739 GO:0005811 GO:0009247 GO:0016491 GO:0030496