GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	GO Labels	GO IDs
Rab GTPase-binding effector protein 2	Q9H5N1	RABEP2	Homo sapiens	9606	GTPase activator activity cell projection organization centrosome ciliary basal body cytosol early endosome endocytosis growth factor activity intracellular membrane-bounded organelle protein transport regulation of cilium assembly	GO:0005096 GO:0005769 GO:0005813 GO:0005829 GO:0006897 GO:0008083 GO:0015031 GO:0030030 GO:0036064 GO:0043231 GO:1902017
Uncharacterized protein	V5AY62	TCDM_05642	Trypanosoma cruzi Dm28c	1416333
Thromboxane-A synthase	P24557	TBXAS1	Homo sapiens	9606	12-hydroxyheptadecatrienoic acid synthase activity cyclooxygenase pathway cytosol endoplasmic reticulum endoplasmic reticulum membrane heme binding hydroperoxy icosatetraenoate dehydratase activity icosanoid metabolic process intracellular chloride ion homeostasis iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen positive regulation of vasoconstriction prostaglandin biosynthetic process response to ethanol response to fatty acid thromboxane-A synthase activity	GO:0001516 GO:0004497 GO:0004796 GO:0005506 GO:0005783 GO:0005789 GO:0005829 GO:0006690 GO:0016705 GO:0019371 GO:0020037 GO:0030644 GO:0036134 GO:0045471 GO:0045907 GO:0070542 GO:0106256
Transcription elongation factor SPT6	V5B3D2	TCDM_10294	Trypanosoma cruzi Dm28c	1416333	nucleobase-containing compound metabolic process positive regulation of transcription elongation by RNA polymerase II	GO:0006139 GO:0032968
Acyl-coenzyme A synthetase ACSM1, mitochondrial	Q08AH1	ACSM1	Homo sapiens	9606	ATP binding CoA-ligase activity GTP binding acyl-CoA metabolic process benzoate metabolic process benzoate-CoA ligase activity blood microparticle butyrate metabolic process butyrate-CoA ligase activity cholesterol homeostasis decanoate-CoA ligase activity energy derivation by oxidation of organic compounds extracellular exosome fatty acid biosynthetic process fatty acid ligase activity fatty acid oxidation fatty-acyl-CoA synthase activity long-chain fatty acid-CoA ligase activity metal ion binding mitochondrial matrix xenobiotic metabolic process	GO:0004321 GO:0004467 GO:0005524 GO:0005525 GO:0005759 GO:0006633 GO:0006637 GO:0006805 GO:0015645 GO:0015980 GO:0016405 GO:0018858 GO:0018874 GO:0019395 GO:0019605 GO:0042632 GO:0046872 GO:0047760 GO:0070062 GO:0072562 GO:0102391
Annexin A1	P10107	Anxa1	Mus musculus	10090	DNA duplex unwinding DNA/DNA annealing activity G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger actin cytoskeleton organization actin filament adaptive immune response alpha-beta T cell differentiation apical plasma membrane arachidonic acid secretion basolateral plasma membrane calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding cell surface cell surface receptor signaling pathway cellular response to glucocorticoid stimulus cellular response to hydrogen peroxide cellular response to vascular endothelial growth factor stimulus collagen-containing extracellular matrix cornified envelope cytoplasm cytosol double-stranded DNA helicase activity early endosome membrane endocrine pancreas development endosome estrous cycle extracellular exosome extracellular space gliogenesis granulocyte chemotaxis hepatocyte differentiation identical protein binding inflammatory response innate immune response insulin secretion keratinocyte differentiation lateral plasma membrane lipid binding localization mast cell granule mitochondrial membrane monocyte chemotaxis motile cilium myoblast migration involved in skeletal muscle regeneration negative regulation of T-helper 2 cell differentiation negative regulation of exocytosis negative regulation of interleukin-8 production negative regulation of protein secretion neutrophil activation neutrophil clearance neutrophil homeostasis nucleoplasm nucleus phagocytic cup phagocytosis phospholipase A2 inhibitor activity phospholipid binding plasma membrane positive regulation of G1/S transition of mitotic cell cycle positive regulation of T cell proliferation positive regulation of T-helper 1 cell differentiation positive regulation of apoptotic process positive regulation of cell migration involved in sprouting angiogenesis positive regulation of interleukin-2 production positive regulation of neutrophil apoptotic process positive regulation of prostaglandin biosynthetic process positive regulation of vesicle fusion positive regulation of wound healing prolactin secretion prostate gland development protein-containing complex regulation of cell population proliferation regulation of cell shape regulation of hormone secretion regulation of inflammatory response regulation of interleukin-1 production regulation of leukocyte migration response to X-ray response to estradiol response to interleukin-1 response to peptide hormone sarcolemma signal transduction single-stranded DNA binding synaptic membrane	GO:0001533 GO:0001780 GO:0001891 GO:0002250 GO:0002548 GO:0002685 GO:0003697 GO:0005509 GO:0005543 GO:0005544 GO:0005615 GO:0005634 GO:0005654 GO:0005737 GO:0005768 GO:0005829 GO:0005884 GO:0005886 GO:0006909 GO:0006954 GO:0007165 GO:0007166 GO:0007187 GO:0008289 GO:0008360 GO:0009986 GO:0010165 GO:0014839 GO:0016323 GO:0016324 GO:0016328 GO:0019834 GO:0030036 GO:0030073 GO:0030216 GO:0030850 GO:0031018 GO:0031340 GO:0031394 GO:0031514 GO:0031901 GO:0031966 GO:0032355 GO:0032508 GO:0032652 GO:0032717 GO:0032743 GO:0032991 GO:0033031 GO:0035924 GO:0036121 GO:0042063 GO:0042102 GO:0042119 GO:0042127 GO:0042383 GO:0042629 GO:0042802 GO:0043065 GO:0043434 GO:0044849 GO:0045087 GO:0045627 GO:0045629 GO:0045920 GO:0046632 GO:0046883 GO:0048306 GO:0050482 GO:0050709 GO:0050727 GO:0051179 GO:0062023 GO:0070062 GO:0070301 GO:0070365 GO:0070459 GO:0070555 GO:0071385 GO:0071621 GO:0090050 GO:0090303 GO:0097060 GO:0097350 GO:1900087 GO:1990814
Auxin response factor	M7ZI10	TRIUR3_33948	Triticum urartu	4572	DNA binding auxin-activated signaling pathway nucleus regulation of DNA-templated transcription	GO:0003677 GO:0005634 GO:0006355 GO:0009734
Tetratricopeptide repeat protein 33	Q6PID6	TTC33	Homo sapiens	9606
Sperm acrosome developmental regulator	Q8IZ16	SPACDR	Homo sapiens	9606	acrosomal vesicle nucleus spermatid development	GO:0001669 GO:0005634 GO:0007286
Longevity-assurance (LAG1) domain-containing protein	B9PSW9	BN1205_032050	Toxoplasma gondii VEG	432359	ceramide biosynthetic process membrane sphingosine N-acyltransferase activity	GO:0016020 GO:0046513 GO:0050291