GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	GO Labels	GO IDs
Ubiquitin-protein ligase	V5BCQ8	TCDM_08181	Trypanosoma cruzi Dm28c	1416333	ligase activity metal ion binding ubiquitin-protein transferase activity	GO:0004842 GO:0016874 GO:0046872
F-actin-capping protein subunit beta	P47757	Capzb	Mus musculus	10090	F-actin capping protein complex Schaffer collateral - CA1 synapse WASH complex Z disc actin binding actin filament binding actin polymerization or depolymerization asymmetric synapse barbed-end actin filament capping brush border cell morphogenesis cell projection organization cortical cytoskeleton cytoskeletal calyx cytoskeleton organization cytosol dendritic spine hippocampal mossy fiber to CA3 synapse lamellipodium lamellipodium assembly membrane negative regulation of filopodium assembly neuronal cell body postsynaptic density regulation of cell morphogenesis regulation of lamellipodium assembly sperm connecting piece	GO:0000902 GO:0003779 GO:0005829 GO:0005903 GO:0007010 GO:0008154 GO:0008290 GO:0010591 GO:0014069 GO:0016020 GO:0022604 GO:0030018 GO:0030027 GO:0030030 GO:0030032 GO:0030863 GO:0032279 GO:0033150 GO:0043025 GO:0043197 GO:0051015 GO:0051016 GO:0051490 GO:0071203 GO:0097224 GO:0098685 GO:0098686
Protein kinase C and casein kinase substrate in neurons protein 3	Q9UKS6	PACSIN3	Homo sapiens	9606	calcium channel inhibitor activity cytoplasm cytoskeletal protein binding cytoskeleton organization cytosol endocytosis endosome extracellular exosome identical protein binding lipid binding negative regulation of calcium ion transport negative regulation of endocytosis phospholipid binding plasma membrane plasma membrane tubulation positive regulation of membrane protein ectodomain proteolysis regulation of endocytosis	GO:0005543 GO:0005737 GO:0005768 GO:0005829 GO:0005886 GO:0006897 GO:0007010 GO:0008092 GO:0008289 GO:0019855 GO:0030100 GO:0042802 GO:0045806 GO:0051044 GO:0051926 GO:0070062 GO:0097320
cDNA FLJ58476, highly similar to Poly(rC)-binding protein 2	B4DLC0	PCBP2	Homo sapiens	9606	RNA binding	GO:0003723
Calcium/calmodulin-dependent protein kinase type II subunit alpha	P11275	Camk2a	Rattus norvegicus	10116	ATP binding G1/S transition of mitotic cell cycle GTPase activating protein binding NMDA selective glutamate receptor signaling pathway Schaffer collateral - CA1 synapse angiotensin-activated signaling pathway axon calcium ion transport calcium- and calmodulin-dependent protein kinase complex calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin dependent kinase signaling pathway calmodulin-dependent protein kinase activity cellular response to interferon-beta cellular response to type II interferon cytoplasm cytosol dendrite dendrite cytoplasm dendrite morphogenesis dendritic spine dendritic spine development glutamate receptor binding glutamatergic postsynaptic density glutamatergic synapse identical protein binding ionotropic glutamate receptor signaling pathway kinase activity metal ion binding mitochondrion negative regulation of hydrolase activity neuron projection neuronal cell body peptidyl-threonine autophosphorylation positive regulation of calcium ion transport positive regulation of cardiac muscle cell apoptotic process positive regulation of receptor signaling pathway via JAK-STAT postsynaptic cytosol postsynaptic density postsynaptic neurotransmitter receptor diffusion trapping postsynaptic specialization membrane presynaptic cytosol protein homodimerization activity protein phosphorylation protein serine kinase activity protein serine/threonine kinase activity regulation of endocannabinoid signaling pathway regulation of mitochondrial membrane permeability involved in apoptotic process regulation of neuron migration regulation of neuronal synaptic plasticity regulation of neurotransmitter receptor localization to postsynaptic specialization membrane regulation of neurotransmitter secretion regulation of protein localization to plasma membrane regulation of synaptic vesicle docking response to ischemia synapse	GO:0000082 GO:0002931 GO:0004674 GO:0004683 GO:0005516 GO:0005524 GO:0005737 GO:0005739 GO:0005829 GO:0005954 GO:0006468 GO:0006816 GO:0009931 GO:0010666 GO:0014069 GO:0016301 GO:0030424 GO:0030425 GO:0032794 GO:0032839 GO:0035235 GO:0035254 GO:0035458 GO:0038166 GO:0042802 GO:0042803 GO:0043005 GO:0043025 GO:0043197 GO:0045202 GO:0046427 GO:0046872 GO:0046928 GO:0048168 GO:0048813 GO:0051346 GO:0051928 GO:0060996 GO:0071346 GO:0098685 GO:0098696 GO:0098970 GO:0098978 GO:0098989 GO:0099004 GO:0099148 GO:0099523 GO:0099524 GO:0099573 GO:0099634 GO:0106310 GO:1902108 GO:1903076 GO:1990443 GO:2000124 GO:2001222
ethanolamine-phosphate cytidylyltransferase	V5BEI8	TCDM_05278	Trypanosoma cruzi Dm28c	1416333	ethanolamine-phosphate cytidylyltransferase activity membrane phosphatidylethanolamine biosynthetic process	GO:0004306 GO:0006646 GO:0016020
Copper transport protein ATOX1	O08997	Atox1	Mus musculus	10090	ATPase binding copper chaperone activity copper ion binding copper ion export copper ion transport copper-dependent protein binding cuprous ion binding cytosol intracellular copper ion homeostasis negative regulation of apoptotic process response to oxidative stress	GO:0005507 GO:0005829 GO:0006825 GO:0006878 GO:0006979 GO:0016531 GO:0032767 GO:0043066 GO:0051117 GO:0060003 GO:1903136
Rhoptry kinase family protein ROP17	B6KB88	BN1205_075890	Toxoplasma gondii VEG	432359	ATP binding phosphorylation protein kinase activity	GO:0004672 GO:0005524 GO:0016310
Proteasome subunit beta type-6	P28072	PSMB6	Homo sapiens	9606	cadherin binding cytoplasm cytosol endopeptidase activity extracellular exosome mitochondrion nucleoplasm nucleus proteasomal protein catabolic process proteasome complex proteasome core complex proteasome core complex, beta-subunit complex proteasome-mediated ubiquitin-dependent protein catabolic process threonine-type endopeptidase activity	GO:0000502 GO:0004175 GO:0004298 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005829 GO:0005839 GO:0010498 GO:0019774 GO:0043161 GO:0045296 GO:0070062
10-formyltetrahydrofolate dehydrogenase	Q8CIF2	Aldh1l1	Mus musculus	10090	10-formyltetrahydrofolate catabolic process biosynthetic process cytoplasm formyltetrahydrofolate dehydrogenase activity one-carbon metabolic process oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	GO:0005737 GO:0006730 GO:0009058 GO:0009258 GO:0016155 GO:0016620