GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name ▲	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A	Q96FX7	TRMT61A	Homo sapiens	9606		mRNA (adenine-N1-)-methyltransferase activity mRNA methylation nucleoplasm nucleus obsolete tRNA (adenine-N1)-methyltransferase activity tRNA (m1A) methyltransferase complex tRNA methylation	GO:0005634 GO:0005654 GO:0016429 GO:0030488 GO:0031515 GO:0061953 GO:0080009
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6	Q9UJA5	TRMT6	Homo sapiens	9606		RNA binding mRNA methylation nucleoplasm nucleus tRNA (m1A) methyltransferase complex tRNA methylation	GO:0003723 GO:0005634 GO:0005654 GO:0030488 GO:0031515 GO:0080009
tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase	Q9UET6	FTSJ1	Homo sapiens	9606	1	S-adenosyl-L-methionine binding cytoplasm cytoplasmic translation cytosol neurogenesis nucleus obsolete tRNA (cytosine-2'-O-)-methyltransferase activity obsolete tRNA (guanosine-2'-O-)-methyltransferase activity tRNA (cytidine(32)-2'-O)-methyltransferase activity tRNA (guanine) methyltransferase activity tRNA methylation tRNA methyltransferase activity tRNA modification tRNA nucleoside ribose methylation wobble position ribose methylation	GO:0002128 GO:0002130 GO:0002181 GO:0005634 GO:0005737 GO:0005829 GO:0006400 GO:0008175 GO:0009020 GO:0016423 GO:0022008 GO:0030488 GO:0052666 GO:0106339 GO:1904047
tRNA (cytosine(34)-C(5))-methyltransferase	H3BKN0	Nsun2	Mus musculus	10090		extracellular region nucleus tRNA (cytidine-5-)-methyltransferase activity tRNA binding	GO:0000049 GO:0005576 GO:0005634 GO:0016428
tRNA (guanine(10)-N2)-methyltransferase homolog	Q9CWH5	Trmt11	Mus musculus	10090		cytoplasm obsolete tRNA (guanine-N2-)-methyltransferase activity tRNA binding	GO:0000049 GO:0004809 GO:0005737
tRNA (guanine(10)-N2)-methyltransferase homolog	E9QKG3	Trmt11	Mus musculus	10090		RNA methylation S-adenosylmethionine-dependent methyltransferase activity ncRNA processing nucleic acid binding	GO:0001510 GO:0003676 GO:0008757 GO:0034470
tRNA (guanine(26)-N(2))-dimethyltransferase	Q9NXH9	TRMT1	Homo sapiens	9606		RNA binding metal ion binding nucleoplasm nucleus obsolete tRNA (guanine-N2-)-methyltransferase activity tRNA N2-guanine methylation tRNA binding tRNA modification	GO:0000049 GO:0002940 GO:0003723 GO:0004809 GO:0005634 GO:0005654 GO:0006400 GO:0046872
tRNA (guanine(26)-N(2))-dimethyltransferase	Q3TX08	Trmt1	Mus musculus	10090	1	metal ion binding nucleus obsolete tRNA (guanine-N2-)-methyltransferase activity tRNA N2-guanine methylation tRNA binding	GO:0000049 GO:0002940 GO:0004809 GO:0005634 GO:0046872
tRNA (guanine(37)-N1)-methyltransferase	P38793	TRM5	Saccharomyces cerevisiae S288C	559292	4	cytoplasm mitochondrial matrix mitochondrial tRNA methylation nucleoplasm nucleus obsolete tRNA (guanine-N1-)-methyltransferase activity tRNA (guanine(37)-N1)-methyltransferase activity tRNA N1-guanine methylation tRNA modification	GO:0002939 GO:0005634 GO:0005654 GO:0005737 GO:0005759 GO:0006400 GO:0009019 GO:0052906 GO:0070901
tRNA (guanine(6)-N2)-methyltransferase THUMP3	Q9BV44	THUMPD3	Homo sapiens	9606		cytoplasm cytosol nucleolus obsolete tRNA (guanine-N2-)-methyltransferase activity tRNA (guanine) methyltransferase activity tRNA N2-guanine methylation tRNA binding tRNA methylation	GO:0000049 GO:0002940 GO:0004809 GO:0005730 GO:0005737 GO:0005829 GO:0016423 GO:0030488