GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	GO Labels	GO IDs
Protein argonaute-3	Q9H9G7	AGO3	Homo sapiens	9606	P-body RISC complex RISC complex assembly RISC-loading complex RNA binding RNA endonuclease activity RNA secondary structure unwinding condensed nuclear chromosome cytoplasm cytoplasmic ribonucleoprotein granule cytosol double-stranded RNA binding endoribonuclease activity, cleaving miRNA-paired mRNA mRNA catabolic process membrane metal ion binding miRNA binding miRNA processing miRNA-mediated gene silencing by inhibition of translation nucleoplasm positive regulation of gene expression positive regulation of non-canonical NF-kappaB signal transduction pre-miRNA processing regulation of stem cell proliferation single-stranded RNA binding	GO:0000794 GO:0000932 GO:0003723 GO:0003725 GO:0003727 GO:0004521 GO:0005654 GO:0005737 GO:0005829 GO:0006402 GO:0010501 GO:0010628 GO:0016020 GO:0016442 GO:0031054 GO:0035196 GO:0035198 GO:0035278 GO:0036464 GO:0046872 GO:0070578 GO:0070922 GO:0072091 GO:0090624 GO:1901224
Inverted formin, FH2 and WH2 domain containing	E9QLA5	Inf2	Mus musculus	10090	actin binding actin cytoskeleton organization perinuclear region of cytoplasm regulation of mitochondrial fission small GTPase binding	GO:0003779 GO:0030036 GO:0031267 GO:0048471 GO:0090140
Mitochondrial Rho GTPase 2	Q8JZN7	Rhot2	Mus musculus	10090	GTP binding GTPase activity actin filament organization calcium ion binding cellular homeostasis mitochondrial inner membrane mitochondrial outer membrane mitochondrial outer membrane permeabilization mitochondrion mitochondrion organization mitochondrion transport along microtubule signal transduction small GTPase mediated signal transduction	GO:0003924 GO:0005509 GO:0005525 GO:0005739 GO:0005741 GO:0005743 GO:0007005 GO:0007015 GO:0007165 GO:0007264 GO:0019725 GO:0047497 GO:0097345
HMG domain-containing protein 4	Q9UGU5	HMGXB4	Homo sapiens	9606	DNA binding NURF complex Wnt signaling pathway endosome to lysosome transport identical protein binding negative regulation of Wnt signaling pathway	GO:0003677 GO:0008333 GO:0016055 GO:0016589 GO:0030178 GO:0042802
E3 ubiquitin-protein ligase RNF113A	O15541	RNF113A	Homo sapiens	9606	DNA repair U2-type precatalytic spliceosome U2-type spliceosomal complex mRNA splicing, via spliceosome metal ion binding negative regulation of chemokine-mediated signaling pathway nuclear speck nucleoplasm nucleus protein ubiquitination snoRNA splicing ubiquitin protein ligase activity	GO:0000398 GO:0005634 GO:0005654 GO:0005684 GO:0006281 GO:0016567 GO:0016607 GO:0034247 GO:0046872 GO:0061630 GO:0070100 GO:0071005
Dihydropyrimidinase-related protein 4	O14531	DPYSL4	Homo sapiens	9606	cytosol filamin binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides nervous system development	GO:0005829 GO:0007399 GO:0016812 GO:0031005
UBX domain-containing protein 4	Q8VCH8	Ubxn4	Mus musculus	10090	cytosol endoplasmic reticulum endoplasmic reticulum membrane nuclear envelope response to unfolded protein ubiquitin-dependent ERAD pathway	GO:0005635 GO:0005783 GO:0005789 GO:0005829 GO:0006986 GO:0030433
F-box only protein 30	Q8TB52	FBXO30	Homo sapiens	9606	cytosol protein ubiquitination ubiquitin protein ligase activity zinc ion binding	GO:0005829 GO:0008270 GO:0016567 GO:0061630
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit	O54734	Ddost	Mus musculus	10090	T cell activation endoplasmic reticulum endoplasmic reticulum membrane enzyme activator activity intracellular membrane-bounded organelle oligosaccharyltransferase complex protein N-linked glycosylation protein N-linked glycosylation via asparagine protein glycosylation regulation of protein stability response to cytokine	GO:0005783 GO:0005789 GO:0006486 GO:0006487 GO:0008047 GO:0008250 GO:0018279 GO:0031647 GO:0034097 GO:0042110 GO:0043231
Supervillin	Q8K4L3	Svil	Mus musculus	10090	actin cytoskeleton actin filament binding actin filament severing actin polymerization or depolymerization barbed-end actin filament capping cell periphery cell projection cleavage furrow costamere cytoplasm cytosol focal adhesion microtubule minus-end midbody muscle cell differentiation nucleoplasm nucleus phosphatidylinositol-4,5-bisphosphate binding plasma membrane podosome positive regulation of cytokinesis sarcolemma skeletal muscle tissue development	GO:0002102 GO:0005546 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0005925 GO:0007519 GO:0008154 GO:0015629 GO:0030496 GO:0032154 GO:0032467 GO:0036449 GO:0042383 GO:0042692 GO:0042995 GO:0043034 GO:0051014 GO:0051015 GO:0051016 GO:0071944