GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Zona pellucida sperm-binding protein 3	P48832	ZP3	Felis catus	9685	6	acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular space humoral immune response mediated by circulating immunoglobulin negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388
Podocalyxin	O00592	PODXL	Homo sapiens	9606	72	apical plasma membrane cell adhesion cell migration centriolar satellite cytoplasm epithelial tube formation extracellular exosome extracellular space filopodium intracellular membrane-bounded organelle lamellipodium membrane raft microvillus membrane negative regulation of cell adhesion negative regulation of cell-cell adhesion nucleolus plasma membrane podocyte development positive regulation of cell migration positive regulation of cell-cell adhesion mediated by integrin regulation of microvillus assembly ruffle slit diaphragm	GO:0001726 GO:0005615 GO:0005730 GO:0005737 GO:0005886 GO:0007155 GO:0007162 GO:0016324 GO:0016477 GO:0022408 GO:0030027 GO:0030175 GO:0030335 GO:0031528 GO:0032534 GO:0033634 GO:0034451 GO:0036057 GO:0043231 GO:0045121 GO:0070062 GO:0072015 GO:0072175
Matrix protein 2	A0A2H4RLC5	M2	Influenza A virus (A/Nicaragua/7400_01/2016(H3N2))	2049845	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
G-protein coupled receptor homolog UL33	P16849	UL33	Human herpesvirus 5 strain AD169	10360	5	G protein-coupled receptor activity evasion of host immune response via modulation of host cytokine network host cell cytoplasm host cell plasma membrane membrane virion component virus-mediated perturbation of host defense response	GO:0004930 GO:0016020 GO:0019049 GO:0020002 GO:0030430 GO:0042785 GO:0044423
Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 1	Q9SSB7	DGR1	Arabidopsis thaliana	3702	1	extracellular region plant-type cell wall	GO:0005576 GO:0009505
Translocon-associated protein subunit beta	A0A0A6YVZ1	Ssr2	Mus musculus	10090	1	endoplasmic reticulum membrane	GO:0005789
von Willebrand factor A domain-containing protein 1	A6QLN9	VWA1	Bos taurus	9913	1	basement membrane collagen-containing extracellular matrix extracellular region ribosome structural constituent of ribosome translation	GO:0003735 GO:0005576 GO:0005604 GO:0005840 GO:0006412 GO:0062023
Paired immunoglobulin-like type 2 receptor beta	Q2YFS2	Pilrb	Mus musculus	10090	3	MHC class I protein binding myeloid dendritic cell activation negative regulation of osteoclast differentiation plasma membrane	GO:0001773 GO:0005886 GO:0042288 GO:0045671
Heat shock 70 kDa protein 6	P17066	HSPA6	Homo sapiens	9606		ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone blood microparticle cellular response to heat centriole chaperone cofactor-dependent protein refolding cytoplasm cytosol enzyme binding extracellular exosome extracellular region ficolin-1-rich granule lumen heat shock protein binding nucleus protein folding chaperone protein refolding response to unfolded protein secretory granule lumen ubiquitin protein ligase binding unfolded protein binding	GO:0005524 GO:0005576 GO:0005634 GO:0005737 GO:0005814 GO:0005829 GO:0006986 GO:0016887 GO:0019899 GO:0031072 GO:0031625 GO:0034605 GO:0034774 GO:0042026 GO:0044183 GO:0051082 GO:0051085 GO:0070062 GO:0072562 GO:0140662 GO:1904813
Matrix protein 2	N0CEZ7	M2	Influenza A virus (A/Texas/24/2010(H3N2))	1318190	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036