GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Large envelope protein	Q9WKC4	S	Hepatitis B virus gorilla/Cameroon/gor97	489546	1	caveolin-mediated endocytosis of virus by host cell fusion of virus membrane with host endosome membrane membrane viral envelope virion attachment to host cell virion membrane	GO:0016020 GO:0019031 GO:0019062 GO:0039654 GO:0055036 GO:0075513
Solute carrier family 22 member 1	O15245	SLC22A1	Homo sapiens	9606	1	(R)-carnitine transmembrane transporter activity acetylcholine transmembrane transporter activity acetylcholine transport acyl carnitine transmembrane transport apical plasma membrane basal plasma membrane basolateral plasma membrane dopamine transport dopamine uptake dopamine:sodium symporter activity epinephrine transport establishment or maintenance of transmembrane electrochemical gradient identical protein binding lateral plasma membrane membrane metanephric proximal tubule development monoamine transmembrane transporter activity monoamine transport neurotransmitter transmembrane transporter activity neurotransmitter transport norepinephrine transport norepinephrine:sodium symporter activity organic anion transmembrane transporter activity organic cation transmembrane transporter activity organic cation transport plasma membrane presynapse prostaglandin transmembrane transporter activity prostaglandin transport purine-containing compound transmembrane transport putrescine transmembrane transporter activity putrescine transport pyrimidine nucleoside transmembrane transporter activity quaternary ammonium group transmembrane transporter activity quaternary ammonium group transport secondary active organic cation transmembrane transporter activity serotonin transport serotonin uptake spermidine transmembrane transporter activity spermidine transport thiamine transmembrane transport thiamine transmembrane transporter activity thiamine transport toxin transmembrane transporter activity toxin transport transport across blood-brain barrier xenobiotic metabolic process xenobiotic transmembrane transporter activity xenobiotic transport xenobiotic transport across blood-brain barrier	GO:0005277 GO:0005326 GO:0005330 GO:0005334 GO:0005886 GO:0006805 GO:0006836 GO:0006837 GO:0008504 GO:0008513 GO:0008514 GO:0009925 GO:0010248 GO:0015101 GO:0015132 GO:0015214 GO:0015234 GO:0015489 GO:0015606 GO:0015651 GO:0015695 GO:0015697 GO:0015732 GO:0015844 GO:0015847 GO:0015848 GO:0015870 GO:0015872 GO:0015874 GO:0015888 GO:0016020 GO:0016323 GO:0016324 GO:0016328 GO:0019534 GO:0042802 GO:0042908 GO:0042910 GO:0048241 GO:0051610 GO:0071934 GO:0072237 GO:0072530 GO:0090494 GO:0098793 GO:0150104 GO:1901235 GO:1901998 GO:1902616 GO:1990962
Matrix protein 2	A0A0G3XSG7	M2	Influenza A virus(A/duck/Guangxi/175D12/2014(H3N6))	1660940	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Pannexin	A0A452E6Q7	PANX1	Capra hircus	9925	1	bleb calcium channel activity endoplasmic reticulum gap junction leak channel activity plasma membrane positive regulation of interleukin-1 beta production signaling receptor binding	GO:0005102 GO:0005262 GO:0005783 GO:0005886 GO:0005921 GO:0022840 GO:0032059 GO:0032731
Potassium channel subfamily K member	A0A8B9TUS7	KCNK1	Anas platyrhynchos	8839	1	dendrite perikaryon potassium channel activity recycling endosome synaptic membrane	GO:0005267 GO:0030425 GO:0043204 GO:0055037 GO:0097060
P2X purinoceptor	A0A8C2VJH1	P2RX4	Chinchilla lanigera	34839	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	A0A8C5XKY6	B3GAT2	Microcebus murinus	30608	1	Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Kinesin-like protein KIF13B	Q9NQT8	KIF13B	Homo sapiens	9606	1	14-3-3 protein binding ATP binding ATP hydrolysis activity T cell activation axon cytoplasm cytoskeleton-dependent intracellular transport kinesin complex microtubule microtubule binding microtubule motor activity microtubule-based movement protein kinase binding protein targeting regulation of axonogenesis signal transduction	GO:0003777 GO:0005524 GO:0005737 GO:0005871 GO:0005874 GO:0006605 GO:0007018 GO:0007165 GO:0008017 GO:0016887 GO:0019901 GO:0030424 GO:0030705 GO:0042110 GO:0050770 GO:0071889
Matrix protein 2	R4L307	M2	Influenza A virus (A/Oklahoma/02/2012(H3N2))	1320967	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Cytoskeleton associated protein 5	F1M949	Ckap5	Rattus norvegicus	10116		central nervous system myelin formation centrosome centrosome cycle cytoplasm cytoplasmic translation dendrite dendritic spine maintenance establishment or maintenance of microtubule cytoskeleton polarity excitatory postsynaptic potential habituation kinetochore locomotory behavior long-term synaptic potentiation mRNA localization resulting in post-transcriptional regulation of gene expression microtubule binding microtubule plus end polymerase microtubule plus-end binding microtubule polymerization neuronal ribonucleoprotein granule perikaryon positive regulation of endocytosis positive regulation of microtubule nucleation postsynapse protein-RNA complex assembly protein-containing complex ribonucleoprotein complex binding spindle organization spindle pole visual learning	GO:0000776 GO:0000922 GO:0002181 GO:0005737 GO:0005813 GO:0007051 GO:0007098 GO:0007626 GO:0008017 GO:0008542 GO:0010609 GO:0022618 GO:0030425 GO:0030951 GO:0032289 GO:0032991 GO:0043021 GO:0043204 GO:0045807 GO:0046785 GO:0046959 GO:0051010 GO:0060079 GO:0060291 GO:0061863 GO:0071598 GO:0090063 GO:0097062 GO:0098794