GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	GO Labels	GO IDs
RelA-associated inhibitor	Q5I1X5	Ppp1r13l	Mus musculus	10090	apoptotic process cardiac muscle contraction cardiac right ventricle morphogenesis cell junction cytosol embryonic camera-type eye development hair cycle identical protein binding intercellular bridge multicellular organism growth multicellular organismal-level homeostasis negative regulation of transcription by RNA polymerase II nucleus positive regulation of cell differentiation post-embryonic development regulation of transcription by RNA polymerase II ventricular cardiac muscle tissue development	GO:0000122 GO:0003215 GO:0003229 GO:0005634 GO:0005829 GO:0006357 GO:0006915 GO:0009791 GO:0030054 GO:0031076 GO:0035264 GO:0042633 GO:0042802 GO:0045171 GO:0045597 GO:0048871 GO:0060048
Protein FAR1-RELATED SEQUENCE 3	Q9ZVC9	FRS3	Arabidopsis thaliana	3702	nucleus plasmodesma regulation of DNA-templated transcription zinc ion binding	GO:0005634 GO:0006355 GO:0008270 GO:0009506
Uncharacterized protein	Q4E5G9	Tc00.1047053511277.250	Trypanosoma cruzi strain CL Brener	353153	catalytic activity isoprenoid biosynthetic process	GO:0003824 GO:0008299
NLR family CARD domain-containing protein 3	Q7RTR2	NLRC3	Homo sapiens	9606	ATP binding T cell activation canonical NF-kappaB signal transduction centriolar satellite cytoplasm cytosol intracellular membrane-bounded organelle intracellular signal transduction negative regulation of NF-kappaB transcription factor activity negative regulation of NLRP3 inflammasome complex assembly negative regulation of canonical NF-kappaB signal transduction negative regulation of cytokine production involved in inflammatory response negative regulation of epithelial cell proliferation negative regulation of fibroblast proliferation negative regulation of inflammatory response negative regulation of innate immune response negative regulation of interferon-alpha production negative regulation of interferon-beta production negative regulation of interleukin-6 production negative regulation of non-canonical NF-kappaB signal transduction negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of tumor necrosis factor production perinuclear region of cytoplasm phosphatidylinositol 3-kinase regulatory subunit binding	GO:0005524 GO:0005737 GO:0005829 GO:0007249 GO:0032088 GO:0032687 GO:0032688 GO:0032715 GO:0032720 GO:0034451 GO:0035556 GO:0036312 GO:0042110 GO:0043124 GO:0043231 GO:0045824 GO:0048147 GO:0048471 GO:0050680 GO:0050728 GO:0051898 GO:1900016 GO:1900226 GO:1901223
Alsin	Q96Q42	ALS2	Homo sapiens	9606	GTPase activator activity behavioral fear response centrosome cytoplasm cytosol dendrite dendritic spine early endosome endosomal transport endosome organization growth cone guanyl-nucleotide exchange factor activity identical protein binding intracellular membrane-bounded organelle lamellipodium locomotory behavior lysosomal transport neuromuscular junction development neuron projection morphogenesis nucleus positive regulation of GTPase activity positive regulation of Rac protein signal transduction positive regulation of protein kinase activity postsynaptic density protein homodimerization activity protein homooligomerization protein localization protein serine/threonine kinase activator activity protein-containing complex receptor recycling regulation of endosome size response to oxidative stress ruffle small GTPase binding synaptic transmission, glutamatergic vesicle	GO:0001662 GO:0001726 GO:0001881 GO:0005085 GO:0005096 GO:0005634 GO:0005737 GO:0005769 GO:0005813 GO:0005829 GO:0006979 GO:0007032 GO:0007041 GO:0007528 GO:0007626 GO:0008104 GO:0014069 GO:0016197 GO:0030027 GO:0030425 GO:0030426 GO:0031267 GO:0031982 GO:0032991 GO:0035022 GO:0035249 GO:0042802 GO:0042803 GO:0043197 GO:0043231 GO:0043539 GO:0043547 GO:0045860 GO:0048812 GO:0051036 GO:0051260
Molecular chaperone MKKS	Q9NPJ1	MKKS	Homo sapiens	9606	ATP binding RNA polymerase II-specific DNA-binding transcription factor binding artery smooth muscle contraction brain morphogenesis cartilage development centrosome cerebral cortex development chaperone-mediated protein complex assembly cilium assembly convergent extension involved in gastrulation cytoplasm cytosol detection of mechanical stimulus involved in sensory perception of sound determination of left/right symmetry developmental process face development fat cell differentiation gonad development heart development heart looping hippocampus development intracellular transport kinociliary basal body melanosome transport motile cilium negative regulation of actin filament polymerization negative regulation of appetite by leptin-mediated signaling pathway negative regulation of blood pressure negative regulation of gene expression non-motile cilium assembly nucleus photoreceptor cell maintenance pigment granule aggregation in cell center positive regulation of multicellular organism growth protein folding regulation of cilium beat frequency involved in ciliary motility regulation of stress fiber assembly sensory perception of smell social behavior spermatid development striatum development unfolded protein binding vasodilation visual perception	GO:0001947 GO:0005524 GO:0005634 GO:0005737 GO:0005813 GO:0005829 GO:0006457 GO:0007286 GO:0007368 GO:0007507 GO:0007601 GO:0007608 GO:0008406 GO:0010629 GO:0014824 GO:0021756 GO:0021766 GO:0021987 GO:0030837 GO:0031514 GO:0032402 GO:0032502 GO:0035176 GO:0038108 GO:0040018 GO:0042311 GO:0045444 GO:0045494 GO:0045776 GO:0046907 GO:0048854 GO:0050910 GO:0051082 GO:0051131 GO:0051216 GO:0051492 GO:0051877 GO:0060027 GO:0060271 GO:0060296 GO:0060324 GO:0061629 GO:1902636 GO:1905515
Polycomb group RING finger protein 2	P35227	PCGF2	Homo sapiens	9606	DNA binding PRC1 complex PcG protein complex anterior/posterior pattern specification apoptotic signaling pathway cellular response to hydrogen peroxide chromatin chromatin remodeling embryonic skeletal system morphogenesis in utero embryonic development metal ion binding negative regulation of apoptotic signaling pathway negative regulation of transcription by RNA polymerase II nuclear body nucleoplasm nucleus promoter-specific chromatin binding sex chromatin	GO:0000122 GO:0000785 GO:0001701 GO:0001739 GO:0003677 GO:0005634 GO:0005654 GO:0006338 GO:0009952 GO:0016604 GO:0031519 GO:0035102 GO:0046872 GO:0048704 GO:0070301 GO:0097190 GO:1990841 GO:2001234
4-hydroxy-2-oxoglutarate aldolase, mitochondrial	Q86XE5	HOGA1	Homo sapiens	9606	(4S)-4-hydroxy-2-oxoglutarate aldolase activity 4-hydroxy-2-oxoglutarate aldolase activity 4-hydroxyproline catabolic process N-acetylneuraminate catabolic process N-acetylneuraminate lyase activity glyoxylate catabolic process glyoxylate metabolic process mitochondrial matrix mitochondrion oxalate metabolic process protein homodimerization activity pyruvate biosynthetic process	GO:0005739 GO:0005759 GO:0008700 GO:0008747 GO:0009436 GO:0019262 GO:0019470 GO:0033609 GO:0042803 GO:0042866 GO:0046487 GO:0106009
Serine-palmitoyl-CoA transferase	V5BLV3	TCDM_02494	Trypanosoma cruzi Dm28c	1416333	biosynthetic process pyridoxal phosphate binding transferase activity	GO:0009058 GO:0016740 GO:0030170
Translation initiation factor IF-2, putative	Q4DQT6	Tc00.1047053511821.110	Trypanosoma cruzi strain CL Brener	353153	GTP binding GTPase activity translation initiation factor activity	GO:0003743 GO:0003924 GO:0005525