GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	GO Labels	GO IDs
Coatomer protein complex subunit beta, putative	V5B518	BN1205_062230	Toxoplasma gondii VEG	432359	Golgi membrane histone acetyltransferase activity intracellular protein transport membrane coat structural molecule activity vesicle-mediated transport	GO:0000139 GO:0004402 GO:0005198 GO:0006886 GO:0016192 GO:0030117
Casein kinase, putative	Q4CSN9	Tc00.1047053507541.40	Trypanosoma cruzi strain CL Brener	353153	ATP binding phosphorylation protein serine/threonine kinase activity	GO:0004674 GO:0005524 GO:0016310
Lanosterol synthase	Q8BLN5	Lss	Mus musculus	10090	cholesterol biosynthetic process endoplasmic reticulum membrane lanosterol synthase activity lipid droplet regulation of protein stability steroid biosynthetic process sterol metabolic process triterpenoid biosynthetic process	GO:0000250 GO:0005789 GO:0005811 GO:0006694 GO:0006695 GO:0016104 GO:0016125 GO:0031647
GAF domain-containing protein	Q4DTJ6	Tc00.1047053507053.90	Trypanosoma cruzi strain CL Brener	353153
Succinate dehydrogenase cytochrome B subunit	Q4D4V5	Tc00.1047053511523.14	Trypanosoma cruzi strain CL Brener	353153	membrane	GO:0016020
serine--tRNA ligase	Q8C483	Sars1	Mus musculus	10090	ATP binding RNA polymerase II cis-regulatory region sequence-specific DNA binding cytoplasmic translation cytosol enzyme binding molecular adaptor activity negative regulation of angiogenesis negative regulation of transcription by RNA polymerase II negative regulation of vascular endothelial growth factor production nucleus protein homodimerization activity selenocysteine incorporation selenocysteine-tRNA ligase activity serine-tRNA ligase activity seryl-tRNA aminoacylation tRNA modification	GO:0000122 GO:0000978 GO:0001514 GO:0002181 GO:0004828 GO:0005524 GO:0005634 GO:0005829 GO:0006400 GO:0006434 GO:0016525 GO:0019899 GO:0042803 GO:0060090 GO:0098619 GO:1904046
Nuclear receptor coactivator	D4A3Q3	Ncoa1	Rattus norvegicus	10116	DNA binding RNA polymerase II transcription regulator complex RNA polymerase II transcription regulatory region sequence-specific DNA binding cellular response to Thyroglobulin triiodothyronine cellular response to hormone stimulus cerebellum development cerebral cortex development chromatin chromatin binding estrous cycle hippocampus development hypothalamus development labyrinthine layer morphogenesis lactation mRNA transcription by RNA polymerase II male gonad development male mating behavior nuclear estrogen receptor binding nuclear receptor binding nuclear receptor coactivator activity nuclear retinoic acid receptor binding nuclear retinoid X receptor binding nucleus positive regulation of DNA-templated transcription positive regulation of apoptotic process positive regulation of female receptivity positive regulation of neuron differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter by galactose protein dimerization activity protein-containing complex protein-containing complex binding regulation of thyroid hormone mediated signaling pathway response to estradiol response to hormone response to progesterone response to retinoic acid transcription coactivator activity transcription regulator complex	GO:0000435 GO:0000785 GO:0000977 GO:0002155 GO:0003677 GO:0003682 GO:0003713 GO:0005634 GO:0005667 GO:0007595 GO:0008584 GO:0009725 GO:0016922 GO:0021549 GO:0021766 GO:0021854 GO:0021987 GO:0030331 GO:0030374 GO:0032355 GO:0032526 GO:0032570 GO:0032870 GO:0032991 GO:0042789 GO:0042974 GO:0043065 GO:0044849 GO:0044877 GO:0045666 GO:0045893 GO:0045925 GO:0045944 GO:0046965 GO:0046983 GO:0060179 GO:0060713 GO:0090575 GO:1904017
STE20-related kinase adapter protein alpha	Q7RTN6	STRADA	Homo sapiens	9606	ATP binding G1 to G0 transition activation of protein kinase activity cytoplasm cytosol intracellular protein-containing complex kinase binding nucleoplasm nucleus protein export from nucleus protein kinase activator activity protein serine/threonine kinase activator activity serine/threonine protein kinase complex	GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006611 GO:0019900 GO:0030295 GO:0032147 GO:0043539 GO:0070314 GO:0140535 GO:1902554
ubiquitinyl hydrolase 1	A0A8I6AL23	Tnfaip3	Rattus norvegicus	10116	B-1 B cell homeostasis DNA binding K63-linked deubiquitinase activity K63-linked polyubiquitin modification-dependent protein binding cell migration cellular response to hydrogen peroxide cellular response to lipopolysaccharide cysteine-type deubiquitinase activity cytoplasm cytoskeleton organization establishment of protein localization to vacuole identical protein binding kinase binding negative regulation of B cell activation negative regulation of CD40 signaling pathway negative regulation of canonical NF-kappaB signal transduction negative regulation of chronic inflammatory response negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of inflammatory response negative regulation of innate immune response negative regulation of interleukin-1 beta production negative regulation of interleukin-2 production negative regulation of interleukin-6 production negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway negative regulation of protein ubiquitination negative regulation of smooth muscle cell proliferation negative regulation of toll-like receptor 3 signaling pathway negative regulation of toll-like receptor 5 signaling pathway negative regulation of tumor necrosis factor production nucleus positive regulation of Wnt signaling pathway positive regulation of hepatocyte proliferation positive regulation of protein catabolic process protease binding protein self-association proteolysis regulation of germinal center formation response to molecule of bacterial origin response to muramyl dipeptide tolerance induction to lipopolysaccharide ubiquitin binding ubiquitin-protein transferase activity zinc ion binding	GO:0001922 GO:0002020 GO:0002237 GO:0002634 GO:0002677 GO:0003677 GO:0004842 GO:0004843 GO:0005634 GO:0005737 GO:0006508 GO:0007010 GO:0008270 GO:0016477 GO:0019900 GO:0030177 GO:0031397 GO:0032495 GO:0032691 GO:0032703 GO:0032715 GO:0032720 GO:0034140 GO:0034148 GO:0042802 GO:0043124 GO:0043130 GO:0043621 GO:0045732 GO:0045824 GO:0048662 GO:0050728 GO:0050869 GO:0061578 GO:0070301 GO:0070429 GO:0070433 GO:0070530 GO:0071222 GO:0072573 GO:0072666 GO:1902042 GO:2000347 GO:2000349 GO:2000352 GO:2001237
Retrotransposon hot spot (RHS) protein	V5B117	TCDM_11175	Trypanosoma cruzi Dm28c	1416333