GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Hemicentin-2	A2AJ76	Hmcn2	Mus musculus	10090	41	axon axon guidance receptor activity basement membrane calcium ion binding cell cortex cell junction cleavage furrow collagen-containing extracellular matrix extracellular region homophilic cell adhesion via plasma membrane adhesion molecules neuronal cell body plasma membrane synapse organization	GO:0005509 GO:0005576 GO:0005604 GO:0005886 GO:0005938 GO:0007156 GO:0008046 GO:0030054 GO:0030424 GO:0032154 GO:0043025 GO:0050808 GO:0062023
MICAL-like protein 2	Q3TN34	Micall2	Mus musculus	10090	41	actin cytoskeleton organization actin filament binding actin filament bundle actin filament polymerization actinin binding bicellular tight junction bicellular tight junction assembly cell-cell junction cytosol endocytic recycling filamin binding metal ion binding neuron projection neuron projection development plasma membrane recycling endosome small GTPase binding substrate adhesion-dependent cell spreading	GO:0005829 GO:0005886 GO:0005911 GO:0005923 GO:0030036 GO:0030041 GO:0031005 GO:0031175 GO:0031267 GO:0032432 GO:0032456 GO:0034446 GO:0042805 GO:0043005 GO:0046872 GO:0051015 GO:0055037 GO:0070830
Cadherin-23	Q9H251	CDH23	Homo sapiens	9606	41	auditory receptor cell stereocilium organization cadherin binding calcium ion binding calcium ion transport calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules catenin complex cell-cell adhesion via plasma-membrane adhesion molecules centrosome cochlear hair cell ribbon synapse equilibrioception homophilic cell adhesion via plasma membrane adhesion molecules kinocilium locomotory behavior membrane obsolete post-embryonic animal organ morphogenesis photoreceptor cell maintenance photoreceptor inner segment photoreceptor ribbon synapse regulation of cytosolic calcium ion concentration response to stimulus sensory perception of light stimulus sensory perception of sound stereocilium stereocilium tip visual perception	GO:0001917 GO:0005509 GO:0005813 GO:0006816 GO:0007156 GO:0007601 GO:0007605 GO:0007626 GO:0016020 GO:0016339 GO:0016342 GO:0032420 GO:0032426 GO:0045296 GO:0045494 GO:0048563 GO:0050896 GO:0050953 GO:0050957 GO:0051480 GO:0060088 GO:0060091 GO:0098683 GO:0098684 GO:0098742
Matrix-remodeling-associated protein 5	Q9NR99	MXRA5	Homo sapiens	9606	41	collagen-containing extracellular matrix extracellular exosome extracellular matrix structural constituent extracellular region response to transforming growth factor beta	GO:0005201 GO:0005576 GO:0062023 GO:0070062 GO:0071559
Glucoamylase	P69328	GLAA	Aspergillus niger	5061	41	endoplasmic reticulum glucan 1,4-alpha-glucosidase activity polysaccharide catabolic process polysaccharide metabolic process starch binding	GO:0000272 GO:0004339 GO:0005783 GO:0005976 GO:2001070
Macrophage colony-stimulating factor 1	P09603	CSF1	Homo sapiens	9606	41	CSF1-CSF1R complex Ras protein signal transduction branching involved in mammary gland duct morphogenesis cytokine activity developmental process involved in reproduction endoplasmic reticulum lumen extracellular region extracellular space growth factor activity homeostasis of number of cells within a tissue identical protein binding inflammatory response innate immune response macrophage colony-stimulating factor receptor binding macrophage colony-stimulating factor signaling pathway macrophage differentiation macrophage homeostasis mammary duct terminal end bud growth mammary gland fat development membrane microglial cell proliferation monocyte activation monocyte differentiation monocyte homeostasis myeloid leukocyte migration neutrophil homeostasis nuclear body osteoclast differentiation osteoclast proliferation perinuclear region of cytoplasm plasma membrane positive regulation of Ras protein signal transduction positive regulation of cell migration positive regulation of cell population proliferation positive regulation of cell-matrix adhesion positive regulation of gene expression positive regulation of macrophage chemotaxis positive regulation of macrophage colony-stimulating factor signaling pathway positive regulation of macrophage derived foam cell differentiation positive regulation of macrophage differentiation positive regulation of macrophage migration positive regulation of microglial cell migration positive regulation of monocyte differentiation positive regulation of mononuclear cell proliferation positive regulation of multicellular organism growth positive regulation of odontogenesis of dentin-containing tooth positive regulation of osteoclast differentiation positive regulation of protein kinase activity positive regulation of protein metabolic process protein homodimerization activity regulation of macrophage derived foam cell differentiation regulation of ossification response to ischemia transmembrane receptor protein tyrosine kinase signaling pathway	GO:0001780 GO:0001954 GO:0002158 GO:0002931 GO:0003006 GO:0005125 GO:0005157 GO:0005576 GO:0005615 GO:0005788 GO:0005886 GO:0006954 GO:0007169 GO:0007265 GO:0008083 GO:0008284 GO:0010628 GO:0010743 GO:0010744 GO:0010759 GO:0016020 GO:0016604 GO:0030224 GO:0030225 GO:0030278 GO:0030316 GO:0030335 GO:0032946 GO:0035702 GO:0038145 GO:0040018 GO:0042117 GO:0042488 GO:0042802 GO:0042803 GO:0045087 GO:0045651 GO:0045657 GO:0045672 GO:0045860 GO:0046579 GO:0048471 GO:0048873 GO:0051247 GO:0060444 GO:0060611 GO:0060763 GO:0061518 GO:0061519 GO:0097529 GO:1902228 GO:1904141 GO:1905523 GO:1990682
Protocadherin Fat 4	Q2PZL6	Fat4	Mus musculus	10090	41	Notch signaling pathway apical part of cell branching involved in ureteric bud morphogenesis calcium ion binding cell-cell adhesion cerebral cortex development condensed mesenchymal cell proliferation digestive tract development establishment of planar polarity fibroblast growth factor receptor signaling pathway heart morphogenesis heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules hippo signaling homophilic cell adhesion via plasma membrane adhesion molecules inner ear receptor cell stereocilium organization kidney development nephron development neurogenesis ossification involved in bone maturation plasma membrane plasma membrane organization regulation of metanephric nephron tubule epithelial cell differentiation	GO:0001658 GO:0001736 GO:0001822 GO:0003007 GO:0005509 GO:0005886 GO:0007009 GO:0007156 GO:0007157 GO:0007219 GO:0008543 GO:0021987 GO:0022008 GO:0035329 GO:0043931 GO:0045177 GO:0048565 GO:0060122 GO:0072006 GO:0072137 GO:0072307 GO:0098609
Low-density lipoprotein receptor-related protein 2	C0HL13	LRP2	Sus scrofa	9823	41	SH3 domain binding apical plasma membrane axon brush border membrane calcium ion binding clathrin-coated pit coronary artery morphogenesis dendrite endosome lumen external side of plasma membrane folate import across plasma membrane male gonad development metal ion transport negative regulation of BMP signaling pathway neural tube closure neuron projection arborization outflow tract septum morphogenesis positive regulation of lysosomal protein catabolic process positive regulation of neurogenesis positive regulation of oligodendrocyte progenitor proliferation protein-folding chaperone binding pulmonary artery morphogenesis receptor complex receptor-mediated endocytosis secondary heart field specification sensory perception of sound vagina development ventricular compact myocardium morphogenesis	GO:0001843 GO:0003139 GO:0003148 GO:0003223 GO:0005509 GO:0005905 GO:0006898 GO:0007605 GO:0008584 GO:0009897 GO:0016324 GO:0017124 GO:0030001 GO:0030424 GO:0030425 GO:0030514 GO:0031526 GO:0031904 GO:0043235 GO:0050769 GO:0051087 GO:0060068 GO:0060982 GO:0061156 GO:0070447 GO:0140058 GO:1904447 GO:1905167
Putative GPI-anchored protein pfl2	Q8TFG9	pfl2	Schizosaccharomyces pombe 972h-	284812	41	cell adhesion mediator activity external side of plasma membrane flocculation	GO:0000128 GO:0009897 GO:0098631
Glucoamylase	P69327	GLAA	Aspergillus awamori	105351	40	glucan 1,4-alpha-glucosidase activity polysaccharide catabolic process starch binding	GO:0000272 GO:0004339 GO:2001070