GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	A0A1S3GJV9	B3gat2	Dipodomys ordii	10020	1	Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Voltage-dependent L-type calcium channel subunit alpha	A0A1S3GBX5	Cacna1d	Dipodomys ordii	10020	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Tartrate-resistant acid phosphatase type 5	A0A1S3GKH3	Acp5	Dipodomys ordii	10020	1	acid phosphatase activity metal ion binding	GO:0003993 GO:0046872
Paraoxonase	A0A1S3GQY0	Pon3	Dipodomys ordii	10020	1	acyl-L-homoserine-lactone lactonohydrolase activity aromatic compound catabolic process arylesterase activity carboxylic acid catabolic process establishment of localization in cell metal ion binding negative regulation of superoxide anion generation protein homodimerization activity renal sodium ion transport	GO:0003096 GO:0004064 GO:0019439 GO:0032929 GO:0042803 GO:0046395 GO:0046872 GO:0051649 GO:0102007
Noggin	A0A1S3GWW2	Nog	Dipodomys ordii	10020	1	BMP signaling pathway atrial cardiac muscle tissue morphogenesis axial mesoderm development cartilage development cell differentiation in hindbrain cranial skeletal system development cytokine binding dorsal/ventral pattern formation embryonic digit morphogenesis embryonic skeletal joint morphogenesis endocardial cushion formation endoderm formation epithelial cell proliferation epithelial to mesenchymal transition exploration behavior extracellular space face morphogenesis fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation heart trabecula morphogenesis in utero embryonic development long-term synaptic potentiation lung morphogenesis membranous septum morphogenesis mesoderm formation middle ear morphogenesis motor neuron axon guidance negative regulation of BMP signaling pathway negative regulation of apoptotic signaling pathway negative regulation of astrocyte differentiation negative regulation of canonical Wnt signaling pathway negative regulation of cardiac epithelial to mesenchymal transition negative regulation of cardiac muscle cell proliferation negative regulation of cartilage development negative regulation of cell migration negative regulation of gene expression negative regulation of osteoblast differentiation negative regulation of transcription by RNA polymerase II neural plate morphogenesis neural tube closure notochord morphogenesis osteoblast differentiation outflow tract morphogenesis pharyngeal arch artery morphogenesis pituitary gland development positive regulation of branching involved in ureteric bud morphogenesis positive regulation of epithelial cell proliferation positive regulation of gene expression positive regulation of glomerulus development positive regulation of transcription by RNA polymerase II presynapse presynaptic modulation of chemical synaptic transmission prostatic bud formation protein homodimerization activity regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation regulation of neuronal synaptic plasticity short-term synaptic potentiation smoothened signaling pathway somatic stem cell population maintenance somite development spinal cord development stem cell differentiation ureteric bud formation ventricular compact myocardium morphogenesis visual learning wound healing	GO:0000122 GO:0001649 GO:0001701 GO:0001706 GO:0001707 GO:0001837 GO:0001839 GO:0001843 GO:0003149 GO:0003151 GO:0003223 GO:0003272 GO:0005615 GO:0007224 GO:0008045 GO:0008542 GO:0009953 GO:0010628 GO:0010629 GO:0019955 GO:0021510 GO:0021533 GO:0021983 GO:0030336 GO:0030509 GO:0030514 GO:0035019 GO:0035640 GO:0042060 GO:0042474 GO:0042733 GO:0042803 GO:0045668 GO:0045944 GO:0048168 GO:0048318 GO:0048570 GO:0048712 GO:0048863 GO:0050673 GO:0050679 GO:0051216 GO:0055009 GO:0060044 GO:0060272 GO:0060291 GO:0060325 GO:0060425 GO:0060513 GO:0060676 GO:0060825 GO:0061037 GO:0061053 GO:0061384 GO:0061626 GO:0062044 GO:0090090 GO:0090190 GO:0090193 GO:0098793 GO:0099171 GO:1904888 GO:1990926 GO:2000313 GO:2001234
A disintegrin and metalloproteinase with thrombospondin motifs 5	A0A1S3G2M4	Adamts5	Dipodomys ordii	10020	2	collagen-containing extracellular matrix extracellular matrix organization extracellular region metalloendopeptidase activity proteolysis zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0030198 GO:0062023
Potassium channel subfamily K member	A0A1S3FKG4	Kcnk7	Dipodomys ordii	10020	1	membrane potassium channel activity	GO:0005267 GO:0016020
Fibroblast growth factor receptor	A0A1S3FZR2	Fgfr1	Dipodomys ordii	10020	8	ATP binding cytoplasmic vesicle cytosol epithelial to mesenchymal transition fibroblast growth factor binding fibroblast growth factor receptor activity heparin binding nucleus phosphorylation plasma membrane positive regulation of MAPK cascade positive regulation of blood vessel endothelial cell migration positive regulation of endothelial cell chemotaxis to fibroblast growth factor positive regulation of neuron differentiation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of vascular endothelial cell proliferation protein homodimerization activity receptor complex receptor-receptor interaction	GO:0001837 GO:0005007 GO:0005524 GO:0005634 GO:0005829 GO:0005886 GO:0008201 GO:0016310 GO:0017134 GO:0031410 GO:0042803 GO:0043235 GO:0043410 GO:0043536 GO:0045666 GO:0051897 GO:0090722 GO:1905564 GO:2000546
Hyaluronidase	A0A1S3FFH9	LOC105988319	Dipodomys ordii	10020	1	carbohydrate metabolic process fusion of sperm to egg plasma membrane involved in single fertilization hyalurononglucosaminidase activity plasma membrane	GO:0004415 GO:0005886 GO:0005975 GO:0007342
Peptidyl-glycine alpha-amidating monooxygenase isoform X2	A0A1S3FNR7	Pam	Dipodomys ordii	10020	1	L-ascorbic acid binding copper ion binding peptide metabolic process peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity transport vesicle membrane	GO:0004504 GO:0004598 GO:0005507 GO:0006518 GO:0030658 GO:0031418