GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Matrix protein 2	H2KHR8	M2	Influenza A virus (A/HaNoi/N317/2007(H3N2))	1052440	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Pre-mRNA-splicing factor RBM22	Q9NW64	RBM22	Homo sapiens	9606	2	Prp19 complex RNA binding U2-type catalytic step 1 spliceosome U2-type catalytic step 2 spliceosome U6 snRNA binding calcium-dependent protein binding catalytic step 2 spliceosome cellular response to xenobiotic stimulus cytoplasm mRNA cis splicing, via spliceosome mRNA splicing, via spliceosome metal ion binding nucleoplasm nucleus positive regulation of RNA splicing positive regulation of protein export from nucleus positive regulation of protein import into nucleus pre-mRNA binding	GO:0000398 GO:0000974 GO:0003723 GO:0005634 GO:0005654 GO:0005737 GO:0017070 GO:0033120 GO:0036002 GO:0042307 GO:0045292 GO:0046827 GO:0046872 GO:0048306 GO:0071006 GO:0071007 GO:0071013 GO:0071466
Matrix protein 2	X2DX29	M2	Influenza A virus (A/New York/1144/2008(H3N2))	1468765	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Ig gamma-2A chain C region	P20760	Igg-2a	Rattus norvegicus	10116	1	antibacterial humoral response antigen binding complement activation, classical pathway immunoglobulin complex, circulating immunoglobulin receptor binding	GO:0003823 GO:0006958 GO:0019731 GO:0034987 GO:0042571
Hexane cyclase gkaB	A0A8F4NUM7	gkaB	Penicillium citrinum	5077	4	isomerase activity	GO:0016853
Zinc finger protein 285	Q96NJ3	ZNF285	Homo sapiens	9606	1	DNA binding DNA-binding transcription factor activity metal ion binding nucleus	GO:0003677 GO:0003700 GO:0005634 GO:0046872
HLA class I antigen (Fragment)	Q707T8	HLA-C	Homo sapiens	9606	1	ER to Golgi transport vesicle membrane antigen processing and presentation cell surface early endosome membrane immune response lumenal side of endoplasmic reticulum membrane phagocytic vesicle membrane plasma membrane recycling endosome membrane	GO:0005886 GO:0006955 GO:0009986 GO:0012507 GO:0019882 GO:0030670 GO:0031901 GO:0055038 GO:0098553
Polypeptide N-acetylgalactosaminyltransferase 5	O88422	Galnt5	Rattus norvegicus	10116	12	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
Angiopoietin-1 receptor	Q06807	TEK	Bos taurus	9913	1	ATP binding Tie signaling pathway actin filament angiogenesis apical plasma membrane basolateral plasma membrane cell differentiation cell surface cell-cell junction centriolar satellite cytoplasm endothelial cell proliferation extracellular region focal adhesion heart development heart trabecula formation identical protein binding intracellular signal transduction membrane raft microvillus negative regulation of angiogenesis negative regulation of endothelial cell apoptotic process obsolete positive regulation of phosphatidylinositol 3-kinase activity peptidyl-tyrosine phosphorylation positive regulation of ERK1 and ERK2 cascade positive regulation of MAPK cascade positive regulation of angiogenesis positive regulation of endothelial cell migration positive regulation of focal adhesion assembly positive regulation of intracellular signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of protein phosphorylation protein autophosphorylation protein tyrosine kinase activity receptor complex regulation of establishment or maintenance of cell polarity sprouting angiogenesis stress fiber substrate adhesion-dependent cell spreading transmembrane receptor protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase signaling pathway	GO:0001525 GO:0001725 GO:0001934 GO:0001935 GO:0002040 GO:0004713 GO:0004714 GO:0005524 GO:0005576 GO:0005737 GO:0005884 GO:0005902 GO:0005911 GO:0005925 GO:0007169 GO:0007507 GO:0009986 GO:0010595 GO:0016323 GO:0016324 GO:0016525 GO:0018108 GO:0030154 GO:0032878 GO:0034446 GO:0034451 GO:0035556 GO:0042802 GO:0043235 GO:0043410 GO:0043552 GO:0045121 GO:0045766 GO:0046777 GO:0048014 GO:0051894 GO:0051897 GO:0060347 GO:0070374 GO:1902533 GO:2000352
Hyaluronidase	A0A6I9P2K1	LOC104955607	Notothenia coriiceps	8208	1	carbohydrate metabolic process hyalurononglucosaminidase activity membrane	GO:0004415 GO:0005975 GO:0016020