GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Protein lin-54 homolog	Q6MZP7	LIN54	Homo sapiens	9606	39	RNA polymerase II transcription repressor complex cell cycle metal ion binding minor groove of adenine-thymine-rich DNA binding nucleoplasm nucleosome organization nucleus regulation of DNA-templated transcription transcription regulatory region nucleic acid binding	GO:0001067 GO:0003680 GO:0005634 GO:0005654 GO:0006355 GO:0007049 GO:0034728 GO:0046872 GO:0090571
Fibrillin-2	Q61555	Fbn2	Mus musculus	10090	39	anatomical structure morphogenesis bone trabecula formation calcium ion binding camera-type eye development collagen-containing extracellular matrix embryonic eye morphogenesis embryonic limb morphogenesis extracellular matrix extracellular matrix structural constituent extracellular region extracellular space hormone activity limb morphogenesis microfibril placenta development positive regulation of bone mineralization positive regulation of osteoblast differentiation regulation of trophoblast cell migration sequestering of TGFbeta in extracellular matrix	GO:0001527 GO:0001890 GO:0005179 GO:0005201 GO:0005509 GO:0005576 GO:0005615 GO:0009653 GO:0030326 GO:0030501 GO:0031012 GO:0035108 GO:0035583 GO:0043010 GO:0045669 GO:0048048 GO:0060346 GO:0062023 GO:1901163
Protocadherin Fat 4	Q6V0I7	FAT4	Homo sapiens	9606	39	calcium ion binding cell-cell adhesion cerebral cortex development extracellular exosome heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules hippo signaling homophilic cell adhesion via plasma membrane adhesion molecules neurogenesis plasma membrane	GO:0005509 GO:0005886 GO:0007156 GO:0007157 GO:0021987 GO:0022008 GO:0035329 GO:0070062 GO:0098609
Cadherin-related tumor suppressor	P33450	ft	Drosophila melanogaster	7227	38	apical plasma membrane apicolateral plasma membrane cadherin binding calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell-cell adhesion cell-cell adhesion mediated by cadherin equator specification establishment of body hair planar orientation establishment of imaginal disc-derived wing hair orientation establishment of ommatidial planar polarity establishment of planar polarity establishment of tissue polarity establishment or maintenance of polarity of larval imaginal disc epithelium heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules imaginal disc growth imaginal disc pattern formation imaginal disc-derived wing morphogenesis microtubule cytoskeleton organization involved in establishment of planar polarity mitochondrion negative regulation of cell population proliferation negative regulation of gene expression negative regulation of growth negative regulation of imaginal disc growth negative regulation of organ growth plasma membrane positive regulation of apoptotic process positive regulation of hippo signaling protein localization involved in establishment of planar polarity pupal development regulation of establishment of planar polarity regulation of growth regulation of imaginal disc growth regulation of protein localization regulation of tube length, open tracheal system tissue development wing disc development	GO:0001736 GO:0001737 GO:0005509 GO:0005739 GO:0005886 GO:0007156 GO:0007157 GO:0007164 GO:0007446 GO:0007447 GO:0007476 GO:0008285 GO:0009888 GO:0010629 GO:0016324 GO:0016327 GO:0016336 GO:0016339 GO:0032880 GO:0035159 GO:0035209 GO:0035220 GO:0035332 GO:0040008 GO:0042067 GO:0043065 GO:0044331 GO:0045296 GO:0045317 GO:0045570 GO:0045571 GO:0045926 GO:0046621 GO:0048105 GO:0090175 GO:0090176 GO:0090251 GO:0098609
Polarized growth protein rax2	O14239	rax2	Schizosaccharomyces pombe 972h-	284812	38	actin filament bundle organization cell cycle cell division endoplasmic reticulum establishment or maintenance of bipolar cell polarity plasma membrane of growing cell tip	GO:0005783 GO:0007049 GO:0051301 GO:0061245 GO:0061572 GO:1902929
Protein bark beetle	M9NDE3	bark	Drosophila melanogaster	7227	38	adherens junction bicellular tight junction carbohydrate binding cell-cell junction maintenance lateral plasma membrane liquid clearance, open tracheal system regulation of tube length, open tracheal system response to endoplasmic reticulum stress septate junction tricellular tight junction tricellular tight junction assembly	GO:0005912 GO:0005918 GO:0005923 GO:0016328 GO:0030246 GO:0034976 GO:0035002 GO:0035159 GO:0045217 GO:0061689 GO:1904274
Receptor-type tyrosine-protein phosphatase eta	Q64455	Ptprj	Mus musculus	10090	38	B cell differentiation beta-catenin binding blood coagulation cadherin binding calcium-mediated signaling using intracellular calcium source cell surface cell-cell junction delta-catenin binding gamma-catenin binding glucose homeostasis heart development immunological synapse mitogen-activated protein kinase binding negative regulation of MAP kinase activity negative regulation of T cell receptor signaling pathway negative regulation of cell growth negative regulation of cell migration negative regulation of cell population proliferation negative regulation of epidermal growth factor receptor signaling pathway negative regulation of insulin receptor signaling pathway negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of platelet-derived growth factor receptor signaling pathway negative regulation of signaling receptor activity negative regulation of vascular permeability oligodendrocyte differentiation peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity phosphatase activity plasma membrane platelet-derived growth factor receptor binding platelet-derived growth factor receptor signaling pathway positive chemotaxis positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis positive regulation of MAPK cascade positive regulation of cell adhesion positive regulation of cell-matrix adhesion positive regulation of focal adhesion assembly positive regulation of macrophage chemotaxis positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation positive regulation of tumor necrosis factor production protein kinase binding protein tyrosine phosphatase activity regulation of cell adhesion ruffle membrane vasculogenesis	GO:0001570 GO:0001772 GO:0001954 GO:0004725 GO:0005161 GO:0005886 GO:0005911 GO:0007507 GO:0007596 GO:0008013 GO:0008285 GO:0009986 GO:0010572 GO:0010642 GO:0010759 GO:0016791 GO:0019901 GO:0030155 GO:0030183 GO:0030308 GO:0030336 GO:0032587 GO:0032760 GO:0035584 GO:0042059 GO:0042593 GO:0043116 GO:0043407 GO:0043410 GO:0045295 GO:0045296 GO:0045785 GO:0046627 GO:0048008 GO:0048709 GO:0050731 GO:0050860 GO:0050918 GO:0051019 GO:0051894 GO:0051897 GO:0051898 GO:0070097 GO:1905451 GO:1990264 GO:2000272
Protocadherin Fat 2	Q5F226	Fat2	Mus musculus	10090	38	Golgi apparatus adherens junction calcium ion binding cell-cell adhesion cell-substrate adhesion epithelial cell migration homophilic cell adhesion via plasma membrane adhesion molecules plasma membrane	GO:0005509 GO:0005794 GO:0005886 GO:0005912 GO:0007156 GO:0010631 GO:0031589 GO:0098609
Fibronectin	P02751	FN1	Homo sapiens	9606	38	acute-phase response angiogenesis apical plasma membrane basement membrane biological process involved in interaction with symbiont blood microparticle calcium-independent cell-matrix adhesion cell adhesion cell-matrix adhesion cell-substrate junction assembly collagen binding collagen-containing extracellular matrix endodermal cell differentiation endoplasmic reticulum lumen endoplasmic reticulum-Golgi intermediate compartment extracellular exosome extracellular matrix extracellular matrix structural constituent extracellular region extracellular space fibrinogen complex heart development heparin binding identical protein binding integrin activation integrin binding integrin-mediated signaling pathway negative regulation of monocyte activation negative regulation of transforming growth factor beta production nervous system development neural crest cell migration involved in autonomic nervous system development peptidase activator activity peptide cross-linking plasma membrane platelet alpha granule lumen positive regulation of axon extension positive regulation of cell population proliferation positive regulation of fibroblast proliferation positive regulation of gene expression positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of substrate-dependent cell migration, cell attachment to substrate protease binding proteoglycan binding regulation of ERK1 and ERK2 cascade regulation of cell shape regulation of protein phosphorylation response to wounding signaling receptor binding substrate adhesion-dependent cell spreading wound healing	GO:0001525 GO:0001932 GO:0002020 GO:0005102 GO:0005178 GO:0005201 GO:0005518 GO:0005576 GO:0005577 GO:0005604 GO:0005615 GO:0005788 GO:0005793 GO:0005886 GO:0006953 GO:0007044 GO:0007155 GO:0007160 GO:0007161 GO:0007229 GO:0007399 GO:0007507 GO:0008201 GO:0008284 GO:0008360 GO:0009611 GO:0010628 GO:0016324 GO:0016504 GO:0018149 GO:0031012 GO:0031093 GO:0033622 GO:0034446 GO:0035987 GO:0042060 GO:0042802 GO:0043394 GO:0045773 GO:0048146 GO:0051702 GO:0051897 GO:0062023 GO:0070062 GO:0070372 GO:0071635 GO:0072562 GO:0150102 GO:1901166 GO:1904237
SCO-spondin	P98167	SSPO	Bos taurus	9913	37	cell adhesion extracellular matrix extracellular space peptidase inhibitor activity	GO:0005615 GO:0007155 GO:0030414 GO:0031012