GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
Voltage-dependent L-type calcium channel subunit alpha	A0A1S3FRT7	Cacna1c	Dipodomys ordii	10020	1	T-tubule calmodulin binding dendrite metal ion binding perikaryon postsynaptic density membrane regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005516 GO:0005891 GO:0030315 GO:0030425 GO:0034765 GO:0043204 GO:0046872 GO:0098839
Peptidyl-glycine alpha-amidating monooxygenase isoform X6	A0A1S3FNS3	Pam	Dipodomys ordii	10020	1	L-ascorbic acid binding copper ion binding peptide metabolic process peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity transport vesicle membrane	GO:0004504 GO:0004598 GO:0005507 GO:0006518 GO:0030658 GO:0031418
Hyaluronidase	A0A1S3FG11	Hyal4	Dipodomys ordii	10020	1	carbohydrate metabolic process cell surface chondroitin sulfate catabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975 GO:0009986 GO:0030207
Protein adenylyltransferase FICD	A0A1S3F1F6	Ficd	Dipodomys ordii	10020	1	ATP binding nucleotidyltransferase activity	GO:0005524 GO:0016779
Paraoxonase	A0A1S3GR72	Pon2	Dipodomys ordii	10020	2	acyl-L-homoserine-lactone lactonohydrolase activity arylesterase activity extracellular region metal ion binding	GO:0004064 GO:0005576 GO:0046872 GO:0102007
Peptidyl-glycine alpha-amidating monooxygenase isoform X5	A0A1S3FLR6	Pam	Dipodomys ordii	10020	1	L-ascorbic acid binding copper ion binding peptide metabolic process peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity transport vesicle membrane	GO:0004504 GO:0004598 GO:0005507 GO:0006518 GO:0030658 GO:0031418
Peptidyl-glycine alpha-amidating monooxygenase isoform X4	A0A1S3FMC8	Pam	Dipodomys ordii	10020	1	L-ascorbic acid binding copper ion binding peptide metabolic process peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity transport vesicle membrane	GO:0004504 GO:0004598 GO:0005507 GO:0006518 GO:0030658 GO:0031418
Voltage-dependent L-type calcium channel subunit alpha	A0A1S3GBI4	Cacna1d	Dipodomys ordii	10020	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
P2X purinoceptor	A0A1S3FPU5	P2rx4	Dipodomys ordii	10020	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Hyaluronidase	A0A1S3G4D2	Hyal2	Dipodomys ordii	10020	1	RNA polymerase II transcription regulator complex apical plasma membrane carbohydrate metabolic process cartilage development cellular response to UV-B cellular response to fibroblast growth factor stimulus cellular response to interleukin-1 cellular response to transforming growth factor beta stimulus cellular response to tumor necrosis factor cytosol defense response to virus endocytic vesicle external side of plasma membrane fusion of virus membrane with host plasma membrane hematopoietic progenitor cell differentiation hyaluronan catabolic process hyaluronic acid binding hyaluronoglucuronidase activity hyalurononglucosaminidase activity lysosome membrane raft microvillus monocyte activation multicellular organismal-level iron ion homeostasis negative regulation of cell growth negative regulation of fibroblast migration negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction perinuclear region of cytoplasm positive regulation of extrinsic apoptotic signaling pathway positive regulation of inflammatory response positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of protein import into nucleus positive regulation of transcription by RNA polymerase II receptor signaling protein tyrosine kinase inhibitor activity receptor tyrosine kinase binding response to antibiotic response to reactive oxygen species skeletal system morphogenesis transcription coactivator activity transforming growth factor beta binding virus receptor activity	GO:0000302 GO:0001618 GO:0002244 GO:0003713 GO:0004415 GO:0005540 GO:0005764 GO:0005829 GO:0005902 GO:0005975 GO:0009897 GO:0010764 GO:0016324 GO:0019064 GO:0030139 GO:0030214 GO:0030294 GO:0030308 GO:0030971 GO:0032755 GO:0032757 GO:0033906 GO:0042117 GO:0042307 GO:0044344 GO:0045121 GO:0045944 GO:0046677 GO:0048471 GO:0048705 GO:0050431 GO:0050729 GO:0051216 GO:0051607 GO:0051898 GO:0060586 GO:0071347 GO:0071356 GO:0071493 GO:0071560 GO:0090575 GO:2001238