GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol ▼	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Protein Wnt-7b (Fragment)	P31289	wnt7b	Xenopus laevis	8355	1	Wnt signaling pathway cell differentiation extracellular region signaling receptor binding system development tissue development	GO:0005102 GO:0005576 GO:0009888 GO:0016055 GO:0030154 GO:0048731
Protein Wnt-7a (Fragment)	P31288	wnt7a	Xenopus laevis	8355	1	Wnt signaling pathway cell differentiation extracellular region signaling receptor binding tissue development	GO:0005102 GO:0005576 GO:0009888 GO:0016055 GO:0030154
Protein Wnt-6 (Fragment)	P28145	wnt6	Thunnus thynnus	8237	1	Wnt signaling pathway animal organ development extracellular region signaling receptor binding	GO:0005102 GO:0005576 GO:0016055 GO:0048513
Protein Wnt-6 (Fragment)	P31287	wnt6	Xenopus laevis	8355	1	Wnt signaling pathway involved in heart development cardiac muscle tissue development embryonic camera-type eye development embryonic digestive tract development extracellular region heart looping morphogen activity negative regulation of DNA-binding transcription factor activity	GO:0001947 GO:0003306 GO:0005576 GO:0016015 GO:0031076 GO:0043433 GO:0048566 GO:0048738
Protein Wnt-5b	Q92050	wnt5b	Danio rerio	7955	4	Wnt signaling pathway, calcium modulating pathway ameboidal-type cell migration angiogenesis canonical Wnt signaling pathway cartilage morphogenesis cell fate commitment cell migration involved in gastrulation chondrocyte differentiation convergent extension convergent extension involved in axis elongation convergent extension involved in gastrulation cytokine activity dorsal convergence embryonic body morphogenesis embryonic cranial skeleton morphogenesis embryonic viscerocranium morphogenesis endochondral ossification endocrine pancreas development extracellular space fin regeneration frizzled binding intracellular sphingolipid homeostasis lymphangiogenesis midbrain-hindbrain boundary morphogenesis muscle cell differentiation neuromast development neuron differentiation ossification otolith development positive regulation of convergent extension involved in gastrulation positive regulation of non-canonical Wnt signaling pathway post-anal tail morphogenesis regulation of Wnt signaling pathway, calcium modulating pathway release of sequestered calcium ion into cytosol signaling receptor binding skeletal system development somite development thrombocyte differentiation unidimensional cell growth	GO:0001501 GO:0001503 GO:0001525 GO:0001667 GO:0001946 GO:0001958 GO:0002062 GO:0002574 GO:0005102 GO:0005109 GO:0005125 GO:0005615 GO:0007223 GO:0008591 GO:0009826 GO:0010172 GO:0021555 GO:0030182 GO:0031018 GO:0031101 GO:0036342 GO:0042074 GO:0042692 GO:0045165 GO:0048701 GO:0048703 GO:0048840 GO:0048884 GO:0051209 GO:0060026 GO:0060027 GO:0060028 GO:0060030 GO:0060070 GO:0060536 GO:0061053 GO:0090156 GO:1904105 GO:2000052
Protein Wnt-5b	P33945	wnt5b	Xenopus laevis	8355	4	Wnt signaling pathway extracellular region muscle cell differentiation positive regulation of convergent extension involved in gastrulation positive regulation of non-canonical Wnt signaling pathway signaling receptor binding	GO:0005102 GO:0005576 GO:0016055 GO:0042692 GO:1904105 GO:2000052
Protein Wnt-5b	O42122	wnt5b	Oryzias latipes	8090	4	animal organ development canonical Wnt signaling pathway cell fate commitment cytokine activity extracellular space frizzled binding muscle cell differentiation neuron differentiation positive regulation of convergent extension involved in gastrulation positive regulation of non-canonical Wnt signaling pathway	GO:0005109 GO:0005125 GO:0005615 GO:0030182 GO:0042692 GO:0045165 GO:0048513 GO:0060070 GO:1904105 GO:2000052
Protein Wnt-5a	P31286	wnt5a	Xenopus laevis	8355	4	Spemann organizer formation Wnt-protein binding anterior/posterior axis specification, embryo canonical Wnt signaling pathway cell migration involved in gastrulation dorsal/ventral axis specification extracellular region frizzled binding negative regulation of canonical Wnt signaling pathway positive regulation of transcription by RNA polymerase II protein-containing complex	GO:0005109 GO:0005576 GO:0008595 GO:0009950 GO:0017147 GO:0032991 GO:0042074 GO:0045944 GO:0060061 GO:0060070 GO:0090090
Protein Wnt-4a	P47793	wnt4a	Danio rerio	7955	2	canonical Wnt signaling pathway cell fate commitment cell migration involved in gastrulation cytokine activity embryonic viscerocranium morphogenesis extracellular space frizzled binding habenula development heart development neuron differentiation positive regulation of DNA-templated transcription regulation of axon extension involved in axon guidance sensory epithelium regeneration	GO:0005109 GO:0005125 GO:0005615 GO:0007507 GO:0021986 GO:0030182 GO:0042074 GO:0045165 GO:0045893 GO:0048703 GO:0048841 GO:0060070 GO:0070654
Protein Wnt-4	P49338	wnt4	Xenopus laevis	8355	2	Wnt signaling pathway embryonic pattern specification extracellular region glomus development nephrostome development pronephric nephron tubule development signaling receptor binding	GO:0005102 GO:0005576 GO:0009880 GO:0016055 GO:0039018 GO:0039020 GO:0072013