GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Fibrinogen alpha chain	P02671	FGA	Homo sapiens	9606	37	adaptive immune response blood coagulation, common pathway blood coagulation, fibrin clot formation blood microparticle cell surface cell-matrix adhesion collagen-containing extracellular matrix endoplasmic reticulum endoplasmic reticulum lumen external side of plasma membrane extracellular exosome extracellular matrix structural constituent extracellular region extracellular space extracellular vesicle fibrinogen complex fibrinolysis induction of bacterial agglutination innate immune response metal ion binding negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway via death domain receptors plasma membrane plasminogen activation platelet aggregation platelet alpha granule platelet alpha granule lumen positive regulation of ERK1 and ERK2 cascade positive regulation of exocytosis positive regulation of heterotypic cell-cell adhesion positive regulation of peptide hormone secretion positive regulation of protein secretion positive regulation of substrate adhesion-dependent cell spreading positive regulation of vasoconstriction protein polymerization protein-containing complex assembly response to calcium ion signaling receptor binding structural molecule activity	GO:0002250 GO:0005102 GO:0005198 GO:0005201 GO:0005576 GO:0005577 GO:0005615 GO:0005783 GO:0005788 GO:0005886 GO:0007160 GO:0009897 GO:0009986 GO:0031091 GO:0031093 GO:0031639 GO:0034116 GO:0042730 GO:0043152 GO:0045087 GO:0045907 GO:0045921 GO:0046872 GO:0050714 GO:0051258 GO:0051592 GO:0062023 GO:0065003 GO:0070062 GO:0070374 GO:0070527 GO:0072377 GO:0072378 GO:0072562 GO:0090277 GO:1900026 GO:1902042 GO:1903561 GO:2000352
Activating transcription factor 7-interacting protein 1	Q6VMQ6	ATF7IP	Homo sapiens	9606	36	ATP hydrolysis activity DNA methylation cytosol negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nuclear body nucleoplasm nucleus positive regulation of DNA methylation-dependent heterochromatin formation positive regulation of DNA-templated transcription protein stabilization regulation of DNA-templated transcription regulation of RNA polymerase II transcription preinitiation complex assembly regulation of protein stability transcription coregulator activity transcription corepressor activity transcription regulator complex	GO:0000122 GO:0003712 GO:0003714 GO:0005634 GO:0005654 GO:0005667 GO:0005829 GO:0006306 GO:0006355 GO:0016604 GO:0016887 GO:0031647 GO:0045892 GO:0045893 GO:0045898 GO:0050821 GO:0090309
Envelope glycoprotein GP350	P68343	BLLF1	Epstein-barr virus strain ag876	82830	36	host cell membrane membrane virion membrane	GO:0016020 GO:0033644 GO:0055036
Laminin subunit alpha-5	O15230	LAMA5	Homo sapiens	9606	36	basement membrane branching involved in salivary gland morphogenesis branching involved in ureteric bud morphogenesis cell migration cilium assembly collagen-containing extracellular matrix extracellular exosome extracellular matrix of synaptic cleft extracellular region extracellular space glutamatergic synapse hair follicle development integrin binding integrin-mediated signaling pathway laminin-10 complex laminin-11 complex laminin-5 complex lung development morphogenesis of a polarized epithelium morphogenesis of embryonic epithelium muscle organ development neuromuscular junction nucleus odontogenesis of dentin-containing tooth postsynapse organization protein localization to plasma membrane regulation of cell adhesion regulation of cell migration regulation of embryonic development regulation of epithelial cell proliferation skeletal system morphogenesis substrate adhesion-dependent cell spreading synaptic cleft trunk neural crest cell migration	GO:0001658 GO:0001738 GO:0001942 GO:0005178 GO:0005576 GO:0005604 GO:0005610 GO:0005615 GO:0005634 GO:0007229 GO:0007517 GO:0016331 GO:0016477 GO:0030155 GO:0030324 GO:0030334 GO:0031594 GO:0034446 GO:0036484 GO:0042475 GO:0043083 GO:0043259 GO:0043260 GO:0045995 GO:0048705 GO:0050678 GO:0060271 GO:0060445 GO:0062023 GO:0070062 GO:0072659 GO:0098965 GO:0098978 GO:0099173
Transcription factor HIVEP2	P31629	HIVEP2	Homo sapiens	9606	36	DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding metal ion binding nucleoplasm nucleus regulation of transcription by RNA polymerase II	GO:0000978 GO:0000981 GO:0003677 GO:0005634 GO:0005654 GO:0006357 GO:0046872
Fibrillin-1	P98133	FBN1	Bos taurus	9913	36	anatomical structure morphogenesis calcium ion binding extracellular matrix extracellular matrix structural constituent extracellular region heparin binding hormone activity microfibril	GO:0001527 GO:0005179 GO:0005201 GO:0005509 GO:0005576 GO:0008201 GO:0009653 GO:0031012
Hemicentin-1	Q96RW7	HMCN1	Homo sapiens	9606	36	actin cytoskeleton organization adherens junction basement membrane basement membrane organization calcium ion binding cell cortex cell cycle cell division cleavage furrow collagen-containing extracellular matrix cytoplasm extracellular exosome extracellular matrix structural constituent heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules muscle tendon junction response to bacterium visual perception	GO:0005201 GO:0005509 GO:0005604 GO:0005737 GO:0005912 GO:0005927 GO:0005938 GO:0007049 GO:0007156 GO:0007157 GO:0007601 GO:0009617 GO:0030036 GO:0032154 GO:0051301 GO:0062023 GO:0070062 GO:0071711
Major surface glycoprotein G	P20895	G	Human orthopneumovirus	11250	36	extracellular region host cell plasma membrane membrane viral entry into host cell virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005576 GO:0016020 GO:0019049 GO:0019062 GO:0020002 GO:0046718 GO:0055036
Fibrillin-1	Q9TV36	FBN1	Sus scrofa	9823	36	anatomical structure morphogenesis calcium ion binding extracellular matrix extracellular matrix structural constituent extracellular region heparin binding hormone activity microfibril	GO:0001527 GO:0005179 GO:0005201 GO:0005509 GO:0005576 GO:0008201 GO:0009653 GO:0031012
Probable JmjC domain-containing histone demethylation protein 2C	Q15652	JMJD1C	Homo sapiens	9606	36	blood coagulation chromatin chromatin DNA binding dioxygenase activity histone H3K9 demethylase activity histone deacetylase complex metal ion binding nuclear thyroid hormone receptor binding nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription coregulator activity	GO:0000118 GO:0000785 GO:0003712 GO:0005654 GO:0006355 GO:0006357 GO:0007596 GO:0031490 GO:0032454 GO:0046872 GO:0046966 GO:0051213