GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name ▲	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
2'-5'-oligoadenylate synthase-like protein	Q15646	OASL	Homo sapiens	9606		DNA binding RNA binding cytoplasm cytosol defense response to virus double-stranded RNA binding innate immune response interleukin-27-mediated signaling pathway membrane negative regulation of viral genome replication nuclear thyroid hormone receptor binding nucleolus nucleoplasm nucleotidyltransferase activity positive regulation of RIG-I signaling pathway response to virus	GO:0003677 GO:0003723 GO:0003725 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0009615 GO:0016020 GO:0016779 GO:0045071 GO:0045087 GO:0046966 GO:0051607 GO:0070106 GO:1900246
2'-5'-oligoadenylate synthase-like protein 1	Q8VI94	Oasl1	Mus musculus	10090		DNA binding cytoplasm cytosol defense response to virus double-stranded RNA binding innate immune response interleukin-27-mediated signaling pathway membrane negative regulation of viral genome replication nucleolus nucleoplasm nucleotidyltransferase activity positive regulation of RIG-I signaling pathway response to virus	GO:0003677 GO:0003725 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0009615 GO:0016020 GO:0016779 GO:0045071 GO:0045087 GO:0051607 GO:0070106 GO:1900246
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	O43598	DNPH1	Homo sapiens	9606		cytosol deoxyribonucleoside 5'-monophosphate N-glycosidase activity deoxyribonucleoside monophosphate catabolic process epithelial cell differentiation extracellular exosome identical protein binding nucleoside metabolic process nucleus positive regulation of cell growth protein homodimerization activity purine nucleotide catabolic process	GO:0005634 GO:0005829 GO:0006195 GO:0009116 GO:0009159 GO:0030307 GO:0030855 GO:0042802 GO:0042803 GO:0070062 GO:0070694
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	V5D5P0	TCDM_09487	Trypanosoma cruzi Dm28c	1416333		2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity glycolytic process metal ion binding	GO:0006096 GO:0046537 GO:0046872
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial	Q9CQ62	Decr1	Mus musculus	10090		2,4-dienoyl-CoA reductase (NADPH) activity NADPH binding catalytic complex cytosol fatty acid beta-oxidation identical protein binding mitochondrion nucleoplasm positive regulation of cold-induced thermogenesis	GO:0005654 GO:0005739 GO:0005829 GO:0006635 GO:0008670 GO:0042802 GO:0070402 GO:0120162 GO:1902494
2,4-dienoyl-coa reductase fadh1	V5AR23	TCDM_09004	Trypanosoma cruzi Dm28c	1416333		FMN binding cytoplasm oxidoreductase activity	GO:0005737 GO:0010181 GO:0016491
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2	Q9CR25	Dph2	Mus musculus	10090		2-(3-amino-3-carboxypropyl)histidine synthase activity 4 iron, 4 sulfur cluster binding metal ion binding protein histidyl modification to diphthamide protein-containing complex	GO:0017183 GO:0032991 GO:0046872 GO:0051539 GO:0090560
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2	Q9BQC3	DPH2	Homo sapiens	9606	3	2-(3-amino-3-carboxypropyl)histidine synthase activity 4 iron, 4 sulfur cluster binding cytosol metal ion binding protein histidyl modification to diphthamide protein-containing complex	GO:0005829 GO:0017183 GO:0032991 GO:0046872 GO:0051539 GO:0090560
2-5A-dependent ribonuclease	Q05823	RNASEL	Homo sapiens	9606	1	ATP binding RNA binding RNA endonuclease activity RNA nuclease activity RNA processing cytosol defense response to virus fat cell differentiation identical protein binding mRNA processing metal ion binding mitochondrial matrix negative regulation of viral genome replication nuclear matrix positive regulation of glucose import positive regulation of transcription by RNA polymerase II protein kinase activity protein phosphorylation rRNA binding rRNA processing regulation of mRNA stability ribonucleoprotein complex binding	GO:0003723 GO:0004521 GO:0004540 GO:0004672 GO:0005524 GO:0005759 GO:0005829 GO:0006364 GO:0006396 GO:0006397 GO:0006468 GO:0016363 GO:0019843 GO:0042802 GO:0043021 GO:0043488 GO:0045071 GO:0045444 GO:0045944 GO:0046326 GO:0046872 GO:0051607
2-Hydroxyacid oxidase 1	Q9WU19	Hao1	Mus musculus	10090		(S)-2-hydroxy-acid oxidase activity FMN binding fatty acid alpha-oxidation glycine biosynthetic process glycolate catabolic process glyoxylate oxidase activity intracellular membrane-bounded organelle peroxisomal matrix peroxisome response to oxidative stress	GO:0001561 GO:0003973 GO:0005777 GO:0005782 GO:0006545 GO:0006979 GO:0010181 GO:0043231 GO:0046296 GO:0047969