GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▲	GO Labels	GO IDs
Glycine receptor subunit alpha-1	P57695	GLRA1	Bos taurus	9913	1	acrosome reaction adult walking behavior cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chloride channel complex chloride transmembrane transport chloride transport dendrite external side of plasma membrane extracellularly glycine-gated chloride channel activity glycine binding glycinergic synapse inhibitory postsynaptic potential inhibitory synapse intracellular membrane-bounded organelle ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential monoatomic ion transport muscle contraction negative regulation of transmission of nerve impulse neuromuscular process controlling posture neuron projection neuronal action potential neuronal cell body neuropeptide signaling pathway perikaryon plasma membrane positive regulation of acrosome reaction postsynaptic membrane regulation of respiratory gaseous exchange by nervous system process response to alcohol response to amino acid righting reflex startle response synapse synaptic transmission, glycinergic taurine binding transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential visual perception zinc ion binding	GO:0001964 GO:0002087 GO:0004888 GO:0005886 GO:0006811 GO:0006821 GO:0006936 GO:0007218 GO:0007340 GO:0007601 GO:0007628 GO:0008270 GO:0009897 GO:0016594 GO:0016934 GO:0019228 GO:0030425 GO:0030977 GO:0034707 GO:0043005 GO:0043025 GO:0043200 GO:0043204 GO:0043231 GO:0045202 GO:0045211 GO:0050884 GO:0051970 GO:0060012 GO:0060013 GO:0060077 GO:0060080 GO:0071230 GO:0071294 GO:0071361 GO:0097305 GO:0098690 GO:0099507 GO:1902476 GO:1904315 GO:2000344
Agouti-signaling protein	Q03288	Asip	Mus musculus	10090	1	adult feeding behavior epigenetic regulation of gene expression extracellular space generation of precursor metabolites and energy genomic imprinting hormone-mediated signaling pathway melanin biosynthetic process melanocortin receptor binding melanosome organization melanosome transport neuropeptide hormone activity pigmentation positive regulation of melanin biosynthetic process type 3 melanocortin receptor binding type 4 melanocortin receptor binding	GO:0005184 GO:0005615 GO:0006091 GO:0008343 GO:0009755 GO:0031779 GO:0031781 GO:0031782 GO:0032402 GO:0032438 GO:0040029 GO:0042438 GO:0043473 GO:0048023 GO:0071514
Matrix protein 2	Q2PHX3	M2	Influenza A virus (A/Canterbury/75/2002(H3N2))	353430	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Hyaluronidase (Fragment)	A0A7L2QXR1	Spam1	Oxylabes madagascariensis	98144	1	carbohydrate metabolic process fusion of sperm to egg plasma membrane involved in single fertilization hyalurononglucosaminidase activity plasma membrane	GO:0004415 GO:0005886 GO:0005975 GO:0007342
Hyaluronidase	F1MSK8	HYAL1	Bos taurus	9913	1	carbohydrate metabolic process cartilage development cellular response to UV-B cellular response to fibroblast growth factor stimulus cellular response to interleukin-1 cellular response to pH cellular response to platelet-derived growth factor stimulus cellular response to tumor necrosis factor chondroitin hydrolase activity chondroitin sulfate catabolic process cytoplasmic vesicle embryonic skeletal joint morphogenesis extracellular space hyaluranon cable hyaluronan biosynthetic process hyaluronan catabolic process hyaluronan synthase activity hyalurononglucosaminidase activity inflammatory response lysosome negative regulation of cell growth positive regulation of G1/S transition of mitotic cell cycle positive regulation of angiogenesis positive regulation of cell adhesion positive regulation of cell growth positive regulation of epithelial cell migration positive regulation of epithelial cell proliferation positive regulation of hyaluranon cable assembly response to antibiotic response to reactive oxygen species response to virus	GO:0000302 GO:0004415 GO:0005615 GO:0005764 GO:0005975 GO:0006954 GO:0009615 GO:0010634 GO:0030207 GO:0030213 GO:0030214 GO:0030307 GO:0030308 GO:0031410 GO:0036117 GO:0036120 GO:0044344 GO:0045766 GO:0045785 GO:0046677 GO:0050501 GO:0050679 GO:0051216 GO:0052757 GO:0060272 GO:0071347 GO:0071356 GO:0071467 GO:0071493 GO:1900087 GO:1900106
Voltage-dependent P/Q-type calcium channel subunit alpha	A0A8C7AF84	CACNA1A	Neogale vison	452646	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Matrix protein 2	A0A193AHQ4	M2	Influenza A virus (A/Hawaii/07/2016(H3N2))	1865854	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
G-protein coupled receptor 171	Q3ZBK9	GPR171	Bos taurus	9913	1	G protein-coupled peptide receptor activity G protein-coupled purinergic nucleotide receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway negative regulation of myeloid cell differentiation neuropeptide binding neuropeptide receptor activity plasma membrane regulation of feeding behavior regulation of sensory perception of pain	GO:0005886 GO:0007186 GO:0007188 GO:0008188 GO:0008528 GO:0042923 GO:0045028 GO:0045638 GO:0051930 GO:0060259
Matrix protein 2	A0A1P8LGS8	M2	Influenza A virus (A/chicken/Ganzhou/GZ43/2016(H3N2))	1931299	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
MHC class I antigen (Fragment)	A0A1C8DT51	HLA-C	Homo sapiens	9606	1