GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Low density lipoprotein receptor-related protein 1	A0A0R4J0I9	Lrp1	Mus musculus	10090	36	alpha-2 macroglobulin receptor activity amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by transcytosis anatomical structure development apolipoprotein binding basolateral plasma membrane calcium ion binding clathrin heavy chain binding early endosome phagocytosis positive regulation of endocytosis positive regulation of lysosomal protein catabolic process positive regulation of protein localization to plasma membrane protein-containing complex binding receptor complex receptor-mediated endocytosis	GO:0005509 GO:0005769 GO:0006898 GO:0006909 GO:0016323 GO:0016964 GO:0032050 GO:0034185 GO:0043235 GO:0044877 GO:0045807 GO:0048856 GO:0150093 GO:0150094 GO:1903078 GO:1905167
Serine/threonine-protein kinase KIC1	P38692	KIC1	Saccharomyces cerevisiae S288C	559292	35	ATP binding budding cell apical bud growth cellular bud cytoplasm fungal-type cell wall organization incipient cellular bud site mating projection tip phosphorylation protein kinase activity protein serine kinase activity protein serine/threonine kinase activity	GO:0000131 GO:0004672 GO:0004674 GO:0005524 GO:0005737 GO:0005933 GO:0007118 GO:0016310 GO:0031505 GO:0043332 GO:0106310
Protein transport protein Sec31A	O94979	SEC31A	Homo sapiens	9606	35	COPII vesicle coat COPII-coated ER to Golgi transport vesicle COPII-coated vesicle cargo loading ER to Golgi transport vesicle membrane calcium-dependent protein binding cytoplasm cytosol endoplasmic reticulum endoplasmic reticulum exit site endoplasmic reticulum membrane endoplasmic reticulum organization endoplasmic reticulum to Golgi vesicle-mediated transport intracellular membrane-bounded organelle intracellular protein transport perinuclear region of cytoplasm response to calcium ion structural molecule activity vesicle coat	GO:0005198 GO:0005737 GO:0005783 GO:0005789 GO:0005829 GO:0006886 GO:0006888 GO:0007029 GO:0012507 GO:0030120 GO:0030127 GO:0030134 GO:0043231 GO:0048306 GO:0048471 GO:0051592 GO:0070971 GO:0090110
Laminin subunit alpha-1	P19137	Lama1	Mus musculus	10090	35	animal organ morphogenesis axon guidance basement membrane blood vessel morphogenesis branching involved in salivary gland morphogenesis camera-type eye development cell adhesion cell surface receptor signaling pathway cell-cell junction collagen-containing extracellular matrix epithelial tube branching involved in lung morphogenesis establishment of epithelial cell apical/basal polarity extracellular matrix extracellular matrix structural constituent extracellular region extracellular space glycosphingolipid binding laminin complex laminin-1 complex laminin-3 complex membrane morphogenesis of an epithelial sheet neuron projection development positive regulation of cell adhesion positive regulation of integrin-mediated signaling pathway positive regulation of muscle cell differentiation protein complex involved in cell-matrix adhesion protein phosphorylation regulation of basement membrane organization regulation of cell migration regulation of embryonic development retina development in camera-type eye retinal blood vessel morphogenesis signaling receptor binding tissue development	GO:0002011 GO:0005102 GO:0005201 GO:0005576 GO:0005604 GO:0005606 GO:0005608 GO:0005615 GO:0005911 GO:0006468 GO:0007155 GO:0007166 GO:0007411 GO:0009887 GO:0009888 GO:0016020 GO:0030334 GO:0031012 GO:0031175 GO:0043010 GO:0043208 GO:0043256 GO:0045198 GO:0045785 GO:0045995 GO:0048514 GO:0051149 GO:0060041 GO:0060441 GO:0060445 GO:0061304 GO:0062023 GO:0098637 GO:0110011 GO:2001046
Albumin	P02768	ALB	Homo sapiens	9606	35	DNA binding Golgi apparatus antioxidant activity blood microparticle cellular response to starvation copper ion binding cytoplasm endoplasmic reticulum endoplasmic reticulum lumen enterobactin binding exogenous protein binding extracellular exosome extracellular region extracellular space fatty acid binding identical protein binding maintenance of mitochondrion location negative regulation of apoptotic process negative regulation of programmed cell death nucleus platelet alpha granule lumen protein-containing complex protein-folding chaperone binding pyridoxal phosphate binding retina homeostasis toxic substance binding	GO:0001895 GO:0003677 GO:0005504 GO:0005507 GO:0005576 GO:0005615 GO:0005634 GO:0005737 GO:0005783 GO:0005788 GO:0005794 GO:0009267 GO:0015643 GO:0016209 GO:0030170 GO:0031093 GO:0032991 GO:0042802 GO:0043066 GO:0043069 GO:0051087 GO:0051659 GO:0070062 GO:0072562 GO:0140272 GO:1903981
Protein crumbs	P10040	crb	Drosophila melanogaster	7227	35	Malpighian tubule morphogenesis Notch binding adherens junction organization amnioserosa maintenance apical constriction apical plasma membrane apical protein localization apicolateral plasma membrane assembly of apicomedial cortex actomyosin calcium ion binding cell division cell morphogenesis involved in Malpighian tubule morphogenesis centrosome localization compound eye morphogenesis compound eye photoreceptor development cytoplasm dorsal closure dorsal closure, amnioserosa morphology change establishment or maintenance of apical/basal cell polarity establishment or maintenance of cell polarity establishment or maintenance of polarity of embryonic epithelium establishment or maintenance of polarity of follicular epithelium liquid clearance, open tracheal system maintenance of apical/basal cell polarity membrane organization negative regulation of Notch signaling pathway negative regulation of organ growth negative regulation of proteasomal ubiquitin-dependent protein catabolic process nervous system development nuclear chromosome segregation nucleus open tracheal system development photoreceptor cell maintenance photoreceptor connecting cilium plasma membrane positive regulation of cell population proliferation positive regulation of hippo signaling protein kinase C binding protein stabilization regulation of imaginal disc growth regulation of intracellular protein transport regulation of protein localization rhabdomere rhabdomere development rhabdomere morphogenesis salivary gland morphogenesis spectrin binding spindle subapical complex trachea development tube morphogenesis wing disc dorsal/ventral pattern formation zonula adherens assembly zonula adherens maintenance	GO:0001745 GO:0003383 GO:0005080 GO:0005112 GO:0005509 GO:0005634 GO:0005737 GO:0005819 GO:0005886 GO:0007163 GO:0007391 GO:0007399 GO:0007424 GO:0007435 GO:0007443 GO:0008284 GO:0016028 GO:0016324 GO:0016327 GO:0016332 GO:0016334 GO:0030507 GO:0032391 GO:0032435 GO:0032880 GO:0033157 GO:0034332 GO:0035002 GO:0035003 GO:0035088 GO:0035090 GO:0035239 GO:0035332 GO:0042051 GO:0042052 GO:0045176 GO:0045186 GO:0045218 GO:0045494 GO:0045570 GO:0045746 GO:0046621 GO:0046664 GO:0046665 GO:0048190 GO:0050821 GO:0051301 GO:0051642 GO:0060438 GO:0061024 GO:0061336 GO:0061541 GO:0098813 GO:0106036
Glutamine and serine-rich protein 1	Q2KHR3	QSER1	Homo sapiens	9606	35	chromosome	GO:0005694
Autotransporter adhesin/invasin TibA	Q9XD84	tibA	Escherichia coli ETEC H10407	316401	35	cell adhesion cell outer membrane	GO:0007155 GO:0009279
Nuclear envelope pore membrane protein POM 121C	A8CG34	POM121C	Homo sapiens	9606	35	RNA export from nucleus endoplasmic reticulum membrane mRNA transport nuclear envelope nuclear localization sequence binding nuclear membrane nuclear pore nucleoplasm protein import into nucleus structural constituent of nuclear pore	GO:0005635 GO:0005643 GO:0005654 GO:0005789 GO:0006405 GO:0006606 GO:0008139 GO:0017056 GO:0031965 GO:0051028
CUB and sushi domain-containing protein 2	Q7Z408	CSMD2	Homo sapiens	9606	35	plasma membrane	GO:0005886