GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
YEATS domain-containing protein 2	Q9ULM3	YEATS2	Homo sapiens	9606	34	ATAC complex NuA4 histone acetyltransferase complex TBP-class protein binding chromatin remodeling histone binding histone reader activity mitotic spindle modification-dependent protein binding negative regulation of transcription by RNA polymerase II nucleoplasm regulation of DNA-templated transcription regulation of cell cycle regulation of cell division regulation of embryonic development regulation of transcription by RNA polymerase II regulation of tubulin deacetylation transcription corepressor activity	GO:0000122 GO:0003714 GO:0005654 GO:0006338 GO:0006355 GO:0006357 GO:0017025 GO:0035267 GO:0042393 GO:0045995 GO:0051302 GO:0051726 GO:0072686 GO:0090043 GO:0140030 GO:0140566 GO:0140672
Protein transport protein Sec23A	Q15436	SEC23A	Homo sapiens	9606	34	COPII vesicle coat COPII-coated vesicle cargo loading ER to Golgi transport vesicle membrane GTPase activator activity Golgi membrane cytosol endoplasmic reticulum exit site endoplasmic reticulum membrane intracellular protein transport perinuclear region of cytoplasm protein localization to plasma membrane zinc ion binding	GO:0000139 GO:0005096 GO:0005789 GO:0005829 GO:0006886 GO:0008270 GO:0012507 GO:0030127 GO:0048471 GO:0070971 GO:0072659 GO:0090110
Nucleobindin-1	Q02818	NUCB1	Homo sapiens	9606	34	DNA binding G-protein alpha-subunit binding Golgi apparatus calcium ion binding endoplasmic reticulum lumen endoplasmic reticulum-Golgi intermediate compartment extracellular exosome extracellular space guanyl-nucleotide exchange factor activity membrane small GTPase mediated signal transduction	GO:0001965 GO:0003677 GO:0005085 GO:0005509 GO:0005615 GO:0005788 GO:0005793 GO:0005794 GO:0007264 GO:0016020 GO:0070062
Forkhead box protein K1	P85037	FOXK1	Homo sapiens	9606	34	14-3-3 protein binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding canonical glycolysis cell differentiation chromatin cytoplasm intracellular glucose homeostasis muscle organ development negative regulation of DNA-templated transcription negative regulation of autophagy nucleoplasm nucleus positive regulation of DNA-templated transcription regulation of glucose metabolic process regulation of transcription by RNA polymerase II response to starvation sequence-specific double-stranded DNA binding transcription cis-regulatory region binding	GO:0000785 GO:0000976 GO:0000978 GO:0000981 GO:0001227 GO:0001678 GO:0003700 GO:0005634 GO:0005654 GO:0005737 GO:0006357 GO:0007517 GO:0010507 GO:0010906 GO:0030154 GO:0042594 GO:0045892 GO:0045893 GO:0061621 GO:0071889 GO:1990837
UPF0648 protein C3H5.09c	Q6LA55	SPAC3H5.09c	Schizosaccharomyces pombe 972h-	284812	34	endoplasmic reticulum-plasma membrane tethering membrane phosphatidylinositol binding protein-membrane adaptor activity	GO:0016020 GO:0035091 GO:0043495 GO:0061817
Histone deacetylase complex subunit SAP130	Q9H0E3	SAP130	Homo sapiens	9606	34	Sin3-type complex negative regulation of cell migration negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II negative regulation of transforming growth factor beta receptor signaling pathway nuclear speck nucleus obsolete Sin3 complex positive regulation of stem cell population maintenance	GO:0000122 GO:0005634 GO:0016580 GO:0016607 GO:0030336 GO:0030512 GO:0070822 GO:1902455 GO:1902459
Transcriptional repressor p66-alpha	Q86YP4	GATAD2A	Homo sapiens	9606	34	DNA methylation NuRD complex chromatin remodeling metal ion binding negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nuclear speck nucleoplasm nucleus positive regulation of DNA-templated transcription protein-macromolecule adaptor activity regulation of cell fate specification regulation of stem cell differentiation sequence-specific DNA binding	GO:0000122 GO:0005634 GO:0005654 GO:0006306 GO:0006338 GO:0016581 GO:0016607 GO:0030674 GO:0042659 GO:0043565 GO:0045892 GO:0045893 GO:0046872 GO:2000736
S-cell enriched with leucine-rich repeat-containing protein slrA	Q54T74	slrA	Dictyostelium discoideum	44689	34	membrane	GO:0016020
Versican core protein	P81282	VCAN	Bos taurus	9913	34	calcium ion binding carbohydrate binding cell adhesion central nervous system development extracellular region extracellular space glial cell differentiation hyaluronic acid binding interphotoreceptor matrix perineuronal net photoreceptor outer segment positive regulation of neuroblast proliferation skeletal system development synapse	GO:0001501 GO:0001750 GO:0002052 GO:0005509 GO:0005540 GO:0005576 GO:0005615 GO:0007155 GO:0007417 GO:0010001 GO:0030246 GO:0033165 GO:0045202 GO:0072534
Endosialin	Q9HCU0	CD248	Homo sapiens	9606	34	anatomical structure regression calcium ion binding carbohydrate binding cell migration cytoplasm endothelial cell apoptotic process external side of plasma membrane extracellular exosome extracellular matrix extracellular matrix binding extracellular matrix protein binding fibroblast migration fibroblast proliferation lymph node development positive regulation of endothelial cell apoptotic process positive regulation of fibroblast proliferation	GO:0005509 GO:0005737 GO:0009897 GO:0010761 GO:0016477 GO:0030246 GO:0031012 GO:0048144 GO:0048146 GO:0048535 GO:0050840 GO:0060033 GO:0070062 GO:0072577 GO:1990430 GO:2000353