GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol ▼	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Protein Wnt-11	Q670P5	wnt11	Xenopus laevis	8355	3	dorsal fin development embryonic axis specification extracellular region gastrulation heart morphogenesis negative regulation of canonical Wnt signaling pathway neural crest cell migration non-canonical Wnt signaling pathway positive regulation of JNK cascade pronephros development regulation of gastrulation signaling receptor binding	GO:0000578 GO:0001755 GO:0003007 GO:0005102 GO:0005576 GO:0007369 GO:0010470 GO:0033337 GO:0035567 GO:0046330 GO:0048793 GO:0090090
Protein Wnt-10b	Q801F7	wnt10b	Danio rerio	7955	2	canonical Wnt signaling pathway cell fate commitment cytokine activity extracellular space frizzled binding midbrain-hindbrain boundary development neuron differentiation	GO:0005109 GO:0005125 GO:0005615 GO:0030182 GO:0030917 GO:0045165 GO:0060070
Protein Wnt-10a	P43446	wnt10a	Danio rerio	7955	2	canonical Wnt signaling pathway cell fate commitment cytokine activity extracellular space frizzled binding neuron differentiation odontogenesis	GO:0005109 GO:0005125 GO:0005615 GO:0030182 GO:0042476 GO:0045165 GO:0060070
Protein Wnt-10 (Fragment)	P31292	wnt10	Xenopus laevis	8355	1	Wnt signaling pathway extracellular region signaling receptor binding	GO:0005102 GO:0005576 GO:0016055
Protein Wnt-1	P10108	wnt1	Xenopus laevis	8355	4	Wnt signaling pathway extracellular region forebrain anterior/posterior pattern specification negative regulation of DNA-templated transcription neural crest cell fate specification signaling receptor binding	GO:0005102 GO:0005576 GO:0014036 GO:0016055 GO:0021797 GO:0045892
Protein Wnt-1	P24257	wnt1	Danio rerio	7955	3	brain segmentation canonical Wnt signaling pathway cell fate commitment cerebellum morphogenesis cytokine activity extracellular space fourth ventricle development frizzled binding hindbrain development midbrain-hindbrain boundary development neuron differentiation	GO:0005109 GO:0005125 GO:0005615 GO:0021587 GO:0021592 GO:0030182 GO:0030902 GO:0030917 GO:0035284 GO:0045165 GO:0060070
Protein Wnt (Fragment)	Q6LCS9	wnt-10B	Mus musculus	10090	1	Wnt signaling pathway extracellular region signaling receptor binding	GO:0005102 GO:0005576 GO:0016055
Protein wntless	B4N5D3	wls	Drosophila willistoni	7260	1	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Protein wntless	B4HEB1	wls	Drosophila sechellia	7238	1	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Protein wntless	Q95ST2	wls	Drosophila melanogaster	7227	1	Golgi apparatus Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endomembrane system endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis imaginal disc-derived wing morphogenesis intracellular protein transport multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005794 GO:0005886 GO:0006886 GO:0007367 GO:0007476 GO:0007480 GO:0008587 GO:0010008 GO:0012505 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157 GO:0099537