GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
protein adenylyltransferase	A0A8J4SQA1	PHET_04623	Paragonimus heterotremus	100268	1	ATP binding nucleotidyltransferase activity	GO:0005524 GO:0016779
P2X purinoceptor	A0A8C2MMZ3	P2rx2	Cricetulus griseus	10029	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Voltage-dependent L-type calcium channel subunit alpha	G3GUU3	I79_001467	Cricetulus griseus	10029	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Phosphoinositide phospholipase C	G3GVA5	Plcd1	Cricetulus griseus	10029	2	calcium ion binding intracellular signal transduction lipid catabolic process phosphatidylinositol phospholipase C activity	GO:0004435 GO:0005509 GO:0016042 GO:0035556
Noggin	A0A3L7GL96	Nog	Cricetulus griseus	10029	1	BMP signaling pathway atrial cardiac muscle tissue morphogenesis axial mesoderm development cartilage development cell differentiation in hindbrain cranial skeletal system development cytokine binding dorsal/ventral pattern formation embryonic digit morphogenesis embryonic skeletal joint morphogenesis endocardial cushion formation endoderm formation epithelial cell proliferation epithelial to mesenchymal transition exploration behavior extracellular space face morphogenesis fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation heart trabecula morphogenesis in utero embryonic development long-term synaptic potentiation lung morphogenesis membranous septum morphogenesis mesoderm formation middle ear morphogenesis motor neuron axon guidance negative regulation of BMP signaling pathway negative regulation of apoptotic signaling pathway negative regulation of astrocyte differentiation negative regulation of canonical Wnt signaling pathway negative regulation of cardiac epithelial to mesenchymal transition negative regulation of cardiac muscle cell proliferation negative regulation of cartilage development negative regulation of cell migration negative regulation of gene expression negative regulation of osteoblast differentiation negative regulation of transcription by RNA polymerase II neural plate morphogenesis neural tube closure notochord morphogenesis osteoblast differentiation outflow tract morphogenesis pharyngeal arch artery morphogenesis pituitary gland development positive regulation of branching involved in ureteric bud morphogenesis positive regulation of epithelial cell proliferation positive regulation of gene expression positive regulation of glomerulus development positive regulation of transcription by RNA polymerase II presynapse presynaptic modulation of chemical synaptic transmission prostatic bud formation protein homodimerization activity regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation regulation of neuronal synaptic plasticity short-term synaptic potentiation smoothened signaling pathway somatic stem cell population maintenance somite development spinal cord development stem cell differentiation ureteric bud formation ventricular compact myocardium morphogenesis visual learning wound healing	GO:0000122 GO:0001649 GO:0001701 GO:0001706 GO:0001707 GO:0001837 GO:0001839 GO:0001843 GO:0003149 GO:0003151 GO:0003223 GO:0003272 GO:0005615 GO:0007224 GO:0008045 GO:0008542 GO:0009953 GO:0010628 GO:0010629 GO:0019955 GO:0021510 GO:0021533 GO:0021983 GO:0030336 GO:0030509 GO:0030514 GO:0035019 GO:0035640 GO:0042060 GO:0042474 GO:0042733 GO:0042803 GO:0045668 GO:0045944 GO:0048168 GO:0048318 GO:0048570 GO:0048712 GO:0048863 GO:0050673 GO:0050679 GO:0051216 GO:0055009 GO:0060044 GO:0060272 GO:0060291 GO:0060325 GO:0060425 GO:0060513 GO:0060676 GO:0060825 GO:0061037 GO:0061053 GO:0061384 GO:0061626 GO:0062044 GO:0090090 GO:0090190 GO:0090193 GO:0098793 GO:0099171 GO:1904888 GO:1990926 GO:2000313 GO:2001234
Hyaluronidase	A0A8C2N168	Hyal2	Cricetulus griseus	10029	1	carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
Pannexin	G3HSP2	Panx1	Cricetulus griseus	10029	1	actin filament binding bleb calcium channel activity endoplasmic reticulum gap junction leak channel activity plasma membrane positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 beta production positive regulation of macrophage cytokine production response to ATP response to ischemia signaling receptor binding	GO:0002931 GO:0005102 GO:0005262 GO:0005783 GO:0005886 GO:0005921 GO:0022840 GO:0032059 GO:0032730 GO:0032731 GO:0033198 GO:0051015 GO:0060907
Low affinity immunoglobulin gamma Fc region receptor III-A	P0DTI4	FCGR3A	Cricetulus griseus	10029	3	IgE binding IgG binding immune system process plasma membrane	GO:0002376 GO:0005886 GO:0019863 GO:0019864
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3	Q9WU47	B3GAT3	Cricetulus griseus	10029	1	Golgi membrane chondroitin sulfate proteoglycan biosynthetic process cis-Golgi network dermatan sulfate proteoglycan biosynthetic process galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity glucuronosyltransferase activity glycosaminoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process metal ion binding positive regulation of catalytic activity positive regulation of intracellular protein transport protein phosphatase activator activity	GO:0000139 GO:0005801 GO:0006024 GO:0015012 GO:0015018 GO:0015020 GO:0043085 GO:0046872 GO:0050650 GO:0050651 GO:0072542 GO:0090316
Bone marrow stromal antigen 2	Q6WRU0	Bst2	Cricetulus griseus	10029	2	Golgi apparatus apical plasma membrane cell surface defense response to virus innate immune response late endosome membrane raft metalloendopeptidase inhibitor activity negative regulation of cell growth negative regulation of cell migration negative regulation of intracellular transport of viral material negative regulation of plasmacytoid dendritic cell cytokine production negative regulation of viral genome replication plasma membrane regulation of actin cytoskeleton organization response to interferon-alpha response to interferon-beta response to type II interferon response to virus side of membrane	GO:0002737 GO:0005770 GO:0005794 GO:0005886 GO:0008191 GO:0009615 GO:0009986 GO:0016324 GO:0030308 GO:0030336 GO:0032956 GO:0034341 GO:0035455 GO:0035456 GO:0045071 GO:0045087 GO:0045121 GO:0051607 GO:0098552 GO:1901253