GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol ▼	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Protein wntless	B4J2W3	wls	Drosophila grimshawi	7222	2	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Protein wntless	B4GZN1	wls	Drosophila persimilis	7234	1	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Protein wntless	B3NGS7	wls	Drosophila erecta	7220	1	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Protein wntless	B3M3X7	wls	Drosophila ananassae	7217	1	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Protein wntless	B4QPR1	wls	Drosophila simulans	7240	1	Golgi membrane Wnt signaling pathway Wnt-protein binding cell projection endoplasmic reticulum membrane endosome membrane imaginal disc-derived wing margin morphogenesis neuromuscular junction plasma membrane positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane	GO:0000139 GO:0005789 GO:0005886 GO:0007367 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0042734 GO:0042995 GO:0045211 GO:0050714
Protein wntless	B4L184	wls	Drosophila mojavensis	7230	2	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Protein wntless	B4PF15	wls	Drosophila yakuba	7245	1	Golgi membrane Wnt signaling pathway Wnt-protein binding cell projection endoplasmic reticulum membrane endosome membrane imaginal disc-derived wing margin morphogenesis neuromuscular junction plasma membrane positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane	GO:0000139 GO:0005789 GO:0005886 GO:0007367 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0042734 GO:0042995 GO:0045211 GO:0050714
Protein wntless	Q2LZ37	wls	Drosophila pseudoobscura pseudoobscura	46245	1	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Protein wntless	B4LC58	wls	Drosophila virilis	7244	2	Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157
Wnt inhibitory factor 1	Q9W6F8	wif1	Xenopus laevis	8355	2	Wnt signaling pathway extracellular region	GO:0005576 GO:0016055