GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Centrosome-associated protein ALMS1	Q8TCU4	ALMS1	Homo sapiens	9606	33	centrosome cilium cytosol endosomal transport microtubule binding positive regulation of cold-induced thermogenesis regulation of centriole replication regulation of stress fiber assembly spindle pole	GO:0000922 GO:0005813 GO:0005829 GO:0005929 GO:0008017 GO:0016197 GO:0046599 GO:0051492 GO:0120162
Envelope glycoprotein gp160	Q9Q714	env	HIV-1 M:H_VI991	388888	32	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Cadherin-4	Q19319	cdh-4	Caenorhabditis elegans	6239	32	axon guidance calcium ion binding cell-cell adhesion cell-cell junction establishment or maintenance of cell polarity homophilic cell adhesion via plasma membrane adhesion molecules neuroblast migration plasma membrane	GO:0005509 GO:0005886 GO:0005911 GO:0007156 GO:0007163 GO:0007411 GO:0097402 GO:0098609
Major surface glycoprotein G	P27023	G	Human respiratory syncytial virus (strain RSB5857)	11254	32	extracellular region host cell plasma membrane membrane viral entry into host cell virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005576 GO:0016020 GO:0019049 GO:0019062 GO:0020002 GO:0046718 GO:0055036
Syndecan-3	O75056	SDC3	Homo sapiens	9606	32	Golgi lumen cell migration cell surface collagen-containing extracellular matrix identical protein binding lysosomal lumen membrane microspike plasma membrane	GO:0005796 GO:0005886 GO:0009986 GO:0016020 GO:0016477 GO:0042802 GO:0043202 GO:0044393 GO:0062023
Stabilin-1	Q8R4Y4	Stab1	Mus musculus	10090	32	calcium ion binding cell adhesion cell-cell signaling cytoplasm defense response to bacterium hyaluronic acid binding inflammatory response low-density lipoprotein particle binding low-density lipoprotein particle receptor activity negative regulation of angiogenesis plasma membrane scavenger receptor activity	GO:0005041 GO:0005044 GO:0005509 GO:0005540 GO:0005737 GO:0005886 GO:0006954 GO:0007155 GO:0007267 GO:0016525 GO:0030169 GO:0042742
Envelope glycoprotein gp160	P04580	env	Human immunodeficiency virus type 1 (ZAIRE 6 ISOLATE)	11708	32	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Envelope glycoprotein gp160	O70902	env	HIV-1 M:H_90CF056	388826	32	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Synapsin-1	O88935	Syn1	Mus musculus	10090	32	ATP binding Golgi apparatus Schaffer collateral - CA1 synapse actin binding axon calcium-dependent protein binding cell body clathrin-sculpted glutamate transport vesicle membrane cytoskeleton dendrite extrinsic component of synaptic vesicle membrane identical protein binding myelin sheath neuron development neurotransmitter secretion postsynaptic density presynapse presynaptic active zone protein kinase binding regulation of short-term neuronal synaptic plasticity regulation of synaptic vesicle cycle regulation of synaptic vesicle exocytosis synapse synapse organization synaptic vesicle synaptic vesicle clustering synaptic vesicle cycle synaptic vesicle membrane synaptonemal complex	GO:0000795 GO:0003779 GO:0005524 GO:0005794 GO:0005856 GO:0007269 GO:0008021 GO:0014069 GO:0019901 GO:0030424 GO:0030425 GO:0030672 GO:0042802 GO:0043209 GO:0044297 GO:0045202 GO:0048172 GO:0048306 GO:0048666 GO:0048786 GO:0050808 GO:0060203 GO:0097091 GO:0098685 GO:0098693 GO:0098793 GO:0098850 GO:0099504 GO:2000300
Spectrin beta chain, non-erythrocytic 1	Q01082	SPTBN1	Homo sapiens	9606	32	GTPase binding Golgi to plasma membrane protein transport M band RNA binding actin binding actin cytoskeleton organization actin filament binding actin filament capping ankyrin binding axolemma cadherin binding calmodulin binding cell junction cell projection central nervous system development central nervous system formation cortical actin cytoskeleton cuticular plate cytoplasm cytosol extracellular exosome glutamatergic synapse membrane assembly mitotic cytokinesis nucleolus phospholipid binding plasma membrane plasma membrane organization positive regulation of interleukin-2 production positive regulation of protein localization to plasma membrane postsynaptic density protein localization to plasma membrane regulation of SMAD protein signal transduction regulation of protein localization to plasma membrane spectrin spectrin-associated cytoskeleton structural constituent of cytoskeleton	GO:0000281 GO:0003723 GO:0003779 GO:0005200 GO:0005516 GO:0005543 GO:0005730 GO:0005737 GO:0005829 GO:0005886 GO:0007009 GO:0007417 GO:0008091 GO:0014069 GO:0014731 GO:0021556 GO:0030036 GO:0030054 GO:0030506 GO:0030673 GO:0030864 GO:0031430 GO:0032437 GO:0032743 GO:0042995 GO:0043001 GO:0045296 GO:0051015 GO:0051020 GO:0051693 GO:0060390 GO:0070062 GO:0071709 GO:0072659 GO:0098978 GO:1903076 GO:1903078