GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name ▲	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
2-oxoglutarate dehydrogenase	V5DCU5	TCDM_06392	Trypanosoma cruzi Dm28c	1416333		dihydrolipoyllysine-residue succinyltransferase activity oxoglutarate dehydrogenase complex tricarboxylic acid cycle	GO:0004149 GO:0006099 GO:0045252
2-oxoglutarate dehydrogenase complex component E1	Q60597	Ogdh	Mus musculus	10090		2-oxoglutarate metabolic process NADH metabolic process cerebellar cortex development generation of precursor metabolites and energy glycolytic process heat shock protein binding hippocampus development histone succinylation metal ion binding mitochondrial membrane mitochondrion nucleus olfactory bulb mitral cell layer development oxoglutarate dehydrogenase (NAD+) activity oxoglutarate dehydrogenase (succinyl-transferring) activity oxoglutarate dehydrogenase complex protein-folding chaperone binding pyramidal neuron development striatum development succinyl-CoA metabolic process tangential migration from the subventricular zone to the olfactory bulb thalamus development thiamine pyrophosphate binding tricarboxylic acid cycle	GO:0004591 GO:0005634 GO:0005739 GO:0006091 GO:0006096 GO:0006099 GO:0006103 GO:0006104 GO:0006734 GO:0021695 GO:0021756 GO:0021766 GO:0021794 GO:0021860 GO:0022028 GO:0030976 GO:0031072 GO:0031966 GO:0034602 GO:0045252 GO:0046872 GO:0051087 GO:0061034 GO:0106077
2-oxoglutarate dehydrogenase complex component E1	Q02218	OGDH	Homo sapiens	9606	1	2-oxoglutarate metabolic process cerebellar cortex development generation of precursor metabolites and energy glycolytic process hippocampus development histone succinylation metal ion binding mitochondrial matrix mitochondrial membrane mitochondrion nucleus olfactory bulb mitral cell layer development oxoglutarate dehydrogenase (NAD+) activity oxoglutarate dehydrogenase (succinyl-transferring) activity oxoglutarate dehydrogenase complex pyramidal neuron development striatum development succinyl-CoA metabolic process tangential migration from the subventricular zone to the olfactory bulb thalamus development thiamine pyrophosphate binding tricarboxylic acid cycle	GO:0004591 GO:0005634 GO:0005739 GO:0005759 GO:0006091 GO:0006096 GO:0006099 GO:0006103 GO:0006104 GO:0021695 GO:0021756 GO:0021766 GO:0021794 GO:0021860 GO:0022028 GO:0030976 GO:0031966 GO:0034602 GO:0045252 GO:0046872 GO:0061034 GO:0106077
2-oxoglutarate dehydrogenase complex component E1	Q5XI78	Ogdh	Rattus norvegicus	10116	1	2-oxoglutarate metabolic process NADH metabolic process cerebellar cortex development generation of precursor metabolites and energy glycolytic process heat shock protein binding hippocampus development histone succinylation metal ion binding mitochondrial membrane mitochondrion nucleus olfactory bulb mitral cell layer development oxoglutarate dehydrogenase (NAD+) activity oxoglutarate dehydrogenase (succinyl-transferring) activity oxoglutarate dehydrogenase complex protein-folding chaperone binding pyramidal neuron development striatum development succinyl-CoA metabolic process tangential migration from the subventricular zone to the olfactory bulb thalamus development thiamine pyrophosphate binding tricarboxylic acid cycle	GO:0004591 GO:0005634 GO:0005739 GO:0006091 GO:0006096 GO:0006099 GO:0006103 GO:0006104 GO:0006734 GO:0021695 GO:0021756 GO:0021766 GO:0021794 GO:0021860 GO:0022028 GO:0030976 GO:0031072 GO:0031966 GO:0034602 GO:0045252 GO:0046872 GO:0051087 GO:0061034 GO:0106077
2-oxoglutarate dehydrogenase subunit	V5BIL1	TCDM_07647	Trypanosoma cruzi Dm28c	1416333		oxoglutarate dehydrogenase (succinyl-transferring) activity thiamine pyrophosphate binding tricarboxylic acid cycle	GO:0004591 GO:0006099 GO:0030976
2-oxoglutarate dehydrogenase-like, mitochondrial	Q9ULD0	OGDHL	Homo sapiens	9606		2-oxoglutarate metabolic process glycolytic process metal ion binding mitochondrial matrix mitochondrion oxoglutarate dehydrogenase (succinyl-transferring) activity oxoglutarate dehydrogenase complex thiamine pyrophosphate binding tricarboxylic acid cycle	GO:0004591 GO:0005739 GO:0005759 GO:0006096 GO:0006099 GO:0006103 GO:0030976 GO:0045252 GO:0046872
2-oxoglutarate receptor 1	Q6Y1R5	Oxgr1	Rattus norvegicus	10116	1	G protein-coupled receptor activity G protein-coupled receptor signaling pathway plasma membrane signaling receptor activity	GO:0004930 GO:0005886 GO:0007186 GO:0038023
2-oxoglutarate receptor 1	Q6IYF8	Oxgr1	Mus musculus	10090	1	AMP binding G protein-coupled adenosine receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway plasma membrane purine nucleoside binding signaling receptor activity	GO:0001609 GO:0001883 GO:0005886 GO:0007186 GO:0007188 GO:0016208 GO:0038023
2-oxoglutarate receptor 1	Q96P68	OXGR1	Homo sapiens	9606	4	G protein-coupled receptor activity G protein-coupled receptor signaling pathway membrane plasma membrane signaling receptor activity	GO:0004930 GO:0005886 GO:0007186 GO:0016020 GO:0038023
2-oxoisovalerate dehydrogenase beta subunit, mitochondrial, putative	Q4DCI2	Tc00.1047053511469.100	Trypanosoma cruzi strain CL Brener	353153		catalytic activity	GO:0003824