GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol ▼	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Wnt inhibitory factor 1	Q9W6F9	wif1	Danio rerio	7955	2	Wnt signaling pathway activin receptor binding anterior/posterior pattern specification blood vessel development cell surface determination of left/right symmetry extracellular region habenula development heart development negative regulation of canonical Wnt signaling pathway nodal binding nodal signaling pathway regulation of canonical Wnt signaling pathway swim bladder development	GO:0001568 GO:0005576 GO:0007368 GO:0007507 GO:0009952 GO:0009986 GO:0016055 GO:0021986 GO:0038092 GO:0038100 GO:0048794 GO:0060828 GO:0070697 GO:0090090
Protein wingless	P09615	wg	Drosophila melanogaster	7227	3	Malpighian tubule bud morphogenesis Malpighian tubule tip cell differentiation Spemann organizer formation anterior/posterior pattern specification, imaginal disc branch fusion, open tracheal system branching morphogenesis of an epithelial tube canonical Wnt signaling pathway canonical Wnt signaling pathway involved in heart development cardioblast differentiation cell elongation involved in imaginal disc-derived wing morphogenesis cell fate commitment cell surface chitin-based larval cuticle pattern formation compound eye morphogenesis cytokine activity determination of genital disc primordium digestive tract morphogenesis dorsal closure dorsal/ventral pattern formation, imaginal disc ectoderm development endoplasmic reticulum epidermis development epithelial cell proliferation involved in Malpighian tubule morphogenesis epithelial cell type specification, open tracheal system extracellular matrix binding extracellular region extracellular space follicle cell of egg chamber development frizzled binding genital disc anterior/posterior pattern formation genital disc sexually dimorphic development glycosaminoglycan binding heart formation heparan sulfate proteoglycan binding hindgut morphogenesis histoblast morphogenesis imaginal disc development imaginal disc-derived wing margin morphogenesis imaginal disc-derived wing morphogenesis labial disc development larval lymph gland hemopoiesis larval visceral muscle development long-term memory lymph gland crystal cell differentiation lymph gland development membrane raft mesoderm development mesoderm morphogenesis morphogen activity multivesicular body negative regulation of DNA endoreduplication negative regulation of cell fate specification negative regulation of hemocyte differentiation neuroblast development neuron differentiation pericardial nephrocyte differentiation plasma membrane positive regulation of cell population proliferation positive regulation of compound eye retinal cell programmed cell death positive regulation of crystal cell differentiation positive regulation of imaginal disc growth positive regulation of programmed cell death positive regulation of stem cell proliferation posterior Malpighian tubule development proboscis development receptor ligand activity regulation of compound eye pigmentation regulation of stem cell proliferation segment polarity determination spiracle morphogenesis, open tracheal system synapse organization synaptic assembly at neuromuscular junction terminal bouton tissue regeneration ventral midline development wing cell fate specification wing disc development	GO:0001745 GO:0005109 GO:0005125 GO:0005539 GO:0005576 GO:0005615 GO:0005771 GO:0005783 GO:0005886 GO:0007367 GO:0007391 GO:0007398 GO:0007418 GO:0007442 GO:0007444 GO:0007448 GO:0007450 GO:0007476 GO:0007488 GO:0007498 GO:0007523 GO:0007616 GO:0008284 GO:0008544 GO:0008587 GO:0009986 GO:0009996 GO:0010002 GO:0014019 GO:0016015 GO:0030182 GO:0030707 GO:0032876 GO:0035147 GO:0035153 GO:0035167 GO:0035170 GO:0035217 GO:0035220 GO:0035224 GO:0035225 GO:0035263 GO:0035277 GO:0035293 GO:0035311 GO:0042246 GO:0042691 GO:0043068 GO:0043195 GO:0043395 GO:0045121 GO:0045165 GO:0045572 GO:0045611 GO:0046672 GO:0048018 GO:0048076 GO:0048332 GO:0048542 GO:0048546 GO:0048728 GO:0048754 GO:0050808 GO:0050840 GO:0051124 GO:0060061 GO:0060070 GO:0060914 GO:0061316 GO:0061320 GO:0061328 GO:0061331 GO:0061332 GO:0061382 GO:0072091 GO:0090254 GO:2000648
Wolframin	Q8IMZ9	wfs1	Drosophila melanogaster	7227	2	adult locomotory behavior calcium ion homeostasis endoplasmic reticulum endoplasmic reticulum unfolded protein response membrane mitochondrion negative regulation of gene expression ubiquitin protein ligase binding	GO:0005739 GO:0005783 GO:0008344 GO:0010629 GO:0016020 GO:0030968 GO:0031625 GO:0055074
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein	Q6NUX0	wfikkn	Danio rerio	7955	1	extracellular space metalloendopeptidase inhibitor activity receptor antagonist activity serine-type endopeptidase inhibitor activity transforming growth factor beta binding transforming growth factor beta receptor signaling pathway	GO:0004867 GO:0005615 GO:0007179 GO:0008191 GO:0048019 GO:0050431
Protein windpipe	Q9W266	wdp	Drosophila melanogaster	7227	4	membrane negative regulation of receptor signaling pathway via JAK-STAT negative regulation of stem cell proliferation plasma membrane positive regulation of endocytosis synaptic target recognition tissue homeostasis trachea development	GO:0001894 GO:0005886 GO:0008039 GO:0016020 GO:0045807 GO:0046426 GO:0060438 GO:2000647
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1	O59866	wbp1	Schizosaccharomyces pombe 972h-	284812	2	endoplasmic reticulum oligosaccharyltransferase complex protein N-linked glycosylation via asparagine	GO:0005783 GO:0008250 GO:0018279
Winged bean acidic lectin (Fragment)	Q9SM56	wba2	Psophocarpus tetragonolobus	3891	1	carbohydrate binding metal ion binding	GO:0030246 GO:0046872
Hemopexin	K4Q670	wap65-1	Plecoglossus altivelis	61084	1	extracellular region heme transmembrane transporter activity intracellular iron ion homeostasis metal ion binding	GO:0005576 GO:0006879 GO:0015232 GO:0046872
Hemopexin	F2QKY3	wap65-1	Lateolabrax japonicus	8164	1	extracellular region heme transmembrane transporter activity intracellular iron ion homeostasis metal ion binding	GO:0005576 GO:0006879 GO:0015232 GO:0046872
Hemopexin	Q8JIP9	wap65	Oryzias latipes	8090	1	extracellular region heme transmembrane transporter activity intracellular iron ion homeostasis metal ion binding	GO:0005576 GO:0006879 GO:0015232 GO:0046872