GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID Gene Symbol Species Taxonomy ID No. of Glycosylation Sites GO Labels GO IDs
  • NSP4
28875
2
  • extracellular region
  • host caveola
  • host cell rough endoplasmic reticulum membrane
  • induction by virus of host autophagy
  • membrane
  • metal ion binding
  • monoatomic ion channel activity
  • protein complex oligomerization
  • toxin activity
  • virus-mediated pore formation in host cell membrane
  • GO:0005216
  • GO:0005576
  • GO:0016020
  • GO:0039520
  • GO:0039707
  • GO:0044155
  • GO:0044169
  • GO:0046872
  • GO:0051259
  • GO:0090729
  • St6galnac5
10090
2
  • Golgi membrane
  • alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
  • ganglioside biosynthetic process
  • glycosphingolipid biosynthetic process
  • oligosaccharide biosynthetic process
  • oligosaccharide metabolic process
  • sialyltransferase activity
  • GO:0000139
  • GO:0001574
  • GO:0001665
  • GO:0006688
  • GO:0008373
  • GO:0009311
  • GO:0009312
  • Cdhr5
10090
1
  • M2
1731833
1
  • host cell plasma membrane
  • membrane
  • monoatomic ion channel activity
  • protein complex oligomerization
  • proton transmembrane transporter activity
  • suppression by virus of host autophagy
  • virion membrane
  • virus-mediated pore formation in host cell membrane
  • GO:0005216
  • GO:0015078
  • GO:0016020
  • GO:0020002
  • GO:0039521
  • GO:0039707
  • GO:0051259
  • GO:0055036
  • Chga
10116
1
  • adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation
  • chromaffin granule
  • defense response to Gram-negative bacterium
  • defense response to Gram-positive bacterium
  • defense response to bacterium
  • extracellular space
  • mast cell activation
  • mast cell chemotaxis
  • mast cell degranulation
  • negative regulation of catecholamine secretion
  • negative regulation of insulin secretion
  • neuronal dense core vesicle
  • ovulation cycle
  • perinuclear region of cytoplasm
  • positive regulation of cAMP-mediated signaling
  • positive regulation of cardiac muscle contraction
  • positive regulation of dense core granule biogenesis
  • positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway
  • positive regulation of protein phosphorylation
  • positive regulation of relaxation of cardiac muscle
  • positive regulation of vasoconstriction
  • protein localization to secretory granule
  • regulation of cytosolic calcium ion concentration
  • regulation of the force of heart contraction
  • secretory granule
  • transport vesicle
  • GO:0001934
  • GO:0002026
  • GO:0002551
  • GO:0005615
  • GO:0030133
  • GO:0030141
  • GO:0033366
  • GO:0033604
  • GO:0042583
  • GO:0042698
  • GO:0042742
  • GO:0043303
  • GO:0043950
  • GO:0045576
  • GO:0045907
  • GO:0046676
  • GO:0048471
  • GO:0050829
  • GO:0050830
  • GO:0051480
  • GO:0060452
  • GO:0086030
  • GO:0098992
  • GO:1900738
  • GO:1901899
  • GO:2000707
  • fgfr2
173247
8
  • ATP binding
  • fibroblast growth factor receptor activity
  • phosphorylation
  • plasma membrane
  • positive regulation of cell population proliferation
  • GO:0005007
  • GO:0005524
  • GO:0005886
  • GO:0008284
  • GO:0016310
  • M2
744767
1
  • host cell plasma membrane
  • membrane
  • monoatomic ion channel activity
  • protein complex oligomerization
  • proton transmembrane transporter activity
  • suppression by virus of host autophagy
  • virion membrane
  • virus-mediated pore formation in host cell membrane
  • GO:0005216
  • GO:0015078
  • GO:0016020
  • GO:0020002
  • GO:0039521
  • GO:0039707
  • GO:0051259
  • GO:0055036
  • ROHU_030620
84645
1
  • dendrite
  • perikaryon
  • potassium channel activity
  • recycling endosome
  • synaptic membrane
  • GO:0005267
  • GO:0030425
  • GO:0043204
  • GO:0055037
  • GO:0097060
  • AMY1B
9606
2
  • alpha-amylase activity
  • calcium ion binding
  • carbohydrate metabolic process
  • chloride ion binding
  • extracellular exosome
  • extracellular space
  • oligosaccharide metabolic process
  • GO:0004556
  • GO:0005509
  • GO:0005615
  • GO:0005975
  • GO:0009311
  • GO:0031404
  • GO:0070062
  • HLA-B
9606
1
Displaying entries 211 - 220 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01