GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Tenascin	P24821	TNC	Homo sapiens	9606	32	basement membrane bud outgrowth involved in lung branching cell adhesion cellular response to prostaglandin D stimulus cellular response to retinoic acid cellular response to vitamin D collagen-containing extracellular matrix endoplasmic reticulum lumen extracellular matrix structural constituent extracellular region extracellular space focal adhesion interstitial matrix membrane mesenchymal-epithelial cell signaling involved in prostate gland development morphogenesis of an epithelium negative regulation of cell adhesion neuromuscular junction development odontogenesis of dentin-containing tooth osteoblast differentiation peripheral nervous system axon regeneration perisynaptic extracellular matrix positive regulation of cell population proliferation positive regulation of gene expression prostate gland epithelium morphogenesis regulation of cell adhesion regulation of cell growth regulation of cell migration regulation of inflammatory response response to ethanol response to fibroblast growth factor response to mechanical stimulus response to wounding syndecan binding tenascin complex	GO:0001558 GO:0001649 GO:0002009 GO:0005201 GO:0005576 GO:0005604 GO:0005614 GO:0005615 GO:0005788 GO:0005925 GO:0007155 GO:0007162 GO:0007528 GO:0008284 GO:0009611 GO:0009612 GO:0010628 GO:0014012 GO:0016020 GO:0030155 GO:0030334 GO:0042475 GO:0045471 GO:0045545 GO:0050727 GO:0060447 GO:0060739 GO:0060740 GO:0062023 GO:0071300 GO:0071305 GO:0071774 GO:0071799 GO:0090733 GO:0098966
Envelope glycoprotein gp160	P04579	env	Human immunodeficiency virus type 1 (RF/HAT ISOLATE)	11701	32	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Zonadhesin	O88799	Zan	Mus musculus	10090	32	binding of sperm to zona pellucida cell adhesion extracellular matrix extracellular matrix binding extracellular space plasma membrane regulation of binding of sperm to zona pellucida	GO:0005615 GO:0005886 GO:0007155 GO:0007339 GO:0031012 GO:0050840 GO:2000359
Envelope glycoprotein gp160	Q9WC69	env	HIV-1 M:J_SE9173	388904	32	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Laminin subunit alpha	Q00174	LanA	Drosophila melanogaster	7227	32	animal organ morphogenesis axon axon guidance basement membrane basement membrane organization cell adhesion mediated by integrin collagen-containing extracellular matrix dorsal trunk growth, open tracheal system extracellular region heart development melanotic encapsulation of foreign target mesoderm development negative regulation of synaptic assembly at neuromuscular junction presynaptic periactive zone regulation of cell adhesion regulation of cell migration regulation of embryonic development signaling receptor binding substrate adhesion-dependent cell spreading synaptic vesicle tissue development	GO:0005102 GO:0005576 GO:0005604 GO:0007411 GO:0007498 GO:0007507 GO:0008021 GO:0009887 GO:0009888 GO:0030155 GO:0030334 GO:0030424 GO:0033627 GO:0034446 GO:0035001 GO:0035011 GO:0036062 GO:0045886 GO:0045995 GO:0062023 GO:0071711
Protein dachsous	Q24292	ds	Drosophila melanogaster	7227	32	anchoring junction apicolateral plasma membrane calcium ion binding cell-cell adhesion establishment of ommatidial planar polarity establishment of planar polarity homophilic cell adhesion via plasma membrane adhesion molecules imaginal disc morphogenesis negative regulation of hippo signaling plasma membrane positive regulation of hippo signaling protein localization involved in establishment of planar polarity	GO:0001736 GO:0005509 GO:0005886 GO:0007156 GO:0007560 GO:0016327 GO:0035331 GO:0035332 GO:0042067 GO:0070161 GO:0090251 GO:0098609
Spike glycoprotein	Q6Q1S2	S	Human coronavirus NL63	277944	32	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endoplasmic reticulum-Golgi intermediate compartment membrane host cell surface receptor binding membrane receptor-mediated virion attachment to host cell viral envelope virion membrane	GO:0016020 GO:0019031 GO:0019064 GO:0039654 GO:0044173 GO:0046789 GO:0046813 GO:0055036 GO:0075509
Stabilin-2	Q8R4U0	Stab2	Mus musculus	10090	32	calcium ion binding cargo receptor activity cell adhesion cytosol defense response to Gram-positive bacterium defense response to bacterium endocytosis external side of plasma membrane hyaluronan catabolic process hyaluronic acid binding low-density lipoprotein particle binding low-density lipoprotein particle receptor activity plasma membrane receptor-mediated endocytosis scavenger receptor activity	GO:0005041 GO:0005044 GO:0005509 GO:0005540 GO:0005829 GO:0005886 GO:0006897 GO:0006898 GO:0007155 GO:0009897 GO:0030169 GO:0030214 GO:0038024 GO:0042742 GO:0050830
Period circadian protein	P07663	per	Drosophila melanogaster	7227	32	behavioral response to cocaine cell body circadian behavior circadian regulation of gene expression circadian rhythm circadian sleep/wake cycle circadian temperature homeostasis copulation courtship behavior cytoplasm cytosol determination of adult lifespan eclosion rhythm entrainment of circadian clock entrainment of circadian clock by photoperiod identical protein binding locomotor rhythm long-term memory male courtship behavior, veined wing generated song production mating behavior negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nucleoplasm nucleus perinuclear region of cytoplasm regulation of circadian rhythm regulation of circadian sleep/wake cycle, sleep regulation of locomotor rhythm regulation of protein phosphorylation response to light stimulus response to oxidative stress response to temperature stimulus rhythmic behavior transcription cis-regulatory region binding transcription coregulator activity transcription corepressor activity transcription corepressor binding	GO:0000122 GO:0000976 GO:0001222 GO:0001932 GO:0003712 GO:0003714 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006979 GO:0007616 GO:0007617 GO:0007619 GO:0007620 GO:0007622 GO:0007623 GO:0008062 GO:0008340 GO:0009266 GO:0009416 GO:0009649 GO:0032922 GO:0042745 GO:0042752 GO:0042802 GO:0043153 GO:0044297 GO:0045187 GO:0045433 GO:0045475 GO:0045892 GO:0048148 GO:0048471 GO:0048512 GO:0060086 GO:1904059
Kininogen-1	P01042	KNG1	Homo sapiens	9606	32	blood coagulation blood microparticle collagen-containing extracellular matrix cysteine-type endopeptidase inhibitor activity endoplasmic reticulum lumen extracellular exosome extracellular region extracellular space heparin binding hormone activity inflammatory response negative regulation of blood coagulation negative regulation of cell adhesion negative regulation of proteolysis plasma membrane platelet alpha granule lumen positive regulation of apoptotic process positive regulation of cytosolic calcium ion concentration signaling receptor binding vasodilation zinc ion binding	GO:0004869 GO:0005102 GO:0005179 GO:0005576 GO:0005615 GO:0005788 GO:0005886 GO:0006954 GO:0007162 GO:0007204 GO:0007596 GO:0008201 GO:0008270 GO:0030195 GO:0031093 GO:0042311 GO:0043065 GO:0045861 GO:0062023 GO:0070062 GO:0072562