GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
5-hydroxytryptamine receptor 2A	P18599	HTR2A	Cricetulus griseus	10029	5	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding G protein-coupled serotonin receptor complex Gq/11-coupled serotonin receptor activity axon behavior caveola cytoplasmic vesicle dendrite glycolytic process identical protein binding intracellular calcium ion homeostasis positive regulation of ERK1 and ERK2 cascade positive regulation of fat cell differentiation positive regulation of glycolytic process positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol biosynthetic process presynapse protein localization to cytoskeleton protein tyrosine kinase activator activity release of sequestered calcium ion into cytosol response to xenobiotic stimulus serotonin binding	GO:0001587 GO:0005901 GO:0006096 GO:0006874 GO:0007610 GO:0009410 GO:0010513 GO:0030296 GO:0030424 GO:0030425 GO:0031410 GO:0042802 GO:0044380 GO:0045600 GO:0045821 GO:0050731 GO:0051209 GO:0051378 GO:0070374 GO:0071886 GO:0098666 GO:0098793
Potassium channel subfamily K member	A0A8C2LT43	Kcnk1	Cricetulus griseus	10029	1	dendrite perikaryon potassium channel activity recycling endosome synaptic membrane	GO:0005267 GO:0030425 GO:0043204 GO:0055037 GO:0097060
P2X purinoceptor	G3HS94	I79_013721	Cricetulus griseus	10029	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Hyaluronidase	A0A8C2MHG1	Hyal1	Cricetulus griseus	10029	1	carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
Peroxisome proliferator-activated receptor gamma	P57797	PPARG	Cricetulus griseus	10029	1	DNA-binding transcription factor activity E-box binding cellular response to insulin stimulus chromatin binding cytoplasm macrophage derived foam cell differentiation nuclear receptor activity nucleus positive regulation of DNA-templated transcription positive regulation of fat cell differentiation positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of circadian rhythm regulation of transcription by RNA polymerase II retinoic acid receptor signaling pathway rhythmic process transcription cis-regulatory region binding zinc ion binding	GO:0000976 GO:0003682 GO:0003700 GO:0004879 GO:0005634 GO:0005737 GO:0006355 GO:0006357 GO:0008270 GO:0010742 GO:0032869 GO:0042752 GO:0045600 GO:0045893 GO:0045944 GO:0048384 GO:0048511 GO:0070888
Protein disulfide isomerase CRELD2	Q60438	CRELD2	Cricetulus griseus	10029	1	calcium ion binding endoplasmic reticulum protein disulfide isomerase activity	GO:0003756 GO:0005509 GO:0005783
Peptidylglycine alpha-amidating monooxygenase	A0A8C2LS40	Pam	Cricetulus griseus	10029	1	L-ascorbic acid binding copper ion binding lyase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen peptide metabolic process transport vesicle membrane	GO:0005507 GO:0006518 GO:0016715 GO:0016829 GO:0030658 GO:0031418
Lysosome-associated membrane glycoprotein 2	P49130	LAMP2	Cricetulus griseus	10029	17	autophagosome maturation autophagosome membrane cellular response to starvation chaperone-mediated autophagy endosome membrane lysosomal membrane lysosomal protein catabolic process lysosome plasma membrane protein stabilization protein targeting protein targeting to lysosome involved in chaperone-mediated autophagy	GO:0000421 GO:0005764 GO:0005765 GO:0005886 GO:0006605 GO:0009267 GO:0010008 GO:0050821 GO:0061684 GO:0061740 GO:0097352 GO:1905146
Pannexin	A0A8C2MWA4	Panx2	Cricetulus griseus	10029	1	channel activity gap junction monoatomic cation transport plasma membrane positive regulation of interleukin-1 production	GO:0005886 GO:0005921 GO:0006812 GO:0015267 GO:0032732
Membrane-bound transcription factor site-2 protease	O54862	MBTPS2	Cricetulus griseus	10029	1	Golgi membrane bone maturation cholesterol metabolic process cytoplasm membrane protein intracellular domain proteolysis metal ion binding metalloendopeptidase activity mitotic G2 DNA damage checkpoint signaling obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress positive regulation of DNA-binding transcription factor activity protein maturation response to endoplasmic reticulum stress	GO:0000139 GO:0004222 GO:0005737 GO:0007095 GO:0008203 GO:0031293 GO:0034976 GO:0046872 GO:0051091 GO:0051604 GO:0070977 GO:1990440