GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
A disintegrin and metalloproteinase with thrombospondin motifs 1	G3I3J3	I79_018001	Cricetulus griseus	10029	3	extracellular matrix extracellular matrix organization extracellular region integrin-mediated signaling pathway metalloendopeptidase activity proteolysis zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0007229 GO:0008270 GO:0030198 GO:0031012
Deoxyribonuclease-1-like 1	Q2QDE6	DNASE1L1	Cricetulus griseus	10029	3	DNA catabolic process DNA nuclease activity endonuclease activity endoplasmic reticulum	GO:0004519 GO:0004536 GO:0005783 GO:0006308
Voltage-dependent L-type calcium channel subunit alpha-1C	G3H863	I79_006562	Cricetulus griseus	10029	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Voltage-dependent L-type calcium channel subunit alpha	A0A8C2LC26	Cacna1s	Cricetulus griseus	10029	2	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Potassium channel subfamily K member	G3IDN4	I79_021817	Cricetulus griseus	10029	1	membrane potassium channel activity	GO:0005267 GO:0016020
Rhodopsin	P28681	RHO	Cricetulus griseus	10029	2	11-cis retinal binding G protein-coupled photoreceptor activity absorption of visible light membrane metal ion binding photoreceptor disc membrane photoreceptor inner segment membrane photoreceptor outer segment membrane plasma membrane rhodopsin mediated signaling pathway visual perception	GO:0005502 GO:0005886 GO:0007601 GO:0008020 GO:0016020 GO:0016038 GO:0016056 GO:0042622 GO:0046872 GO:0060342 GO:0097381
Protein adenylyltransferase FICD	A0A061I403	FICD	Cricetulus griseus	10029	1	AMPylase activity ATP binding Hsp70 protein binding endoplasmic reticulum membrane protein adenylylation protein adenylylhydrolase activity protein deadenylylation protein homodimerization activity protein-folding chaperone binding regulation of IRE1-mediated unfolded protein response response to endoplasmic reticulum stress response to unfolded protein	GO:0005524 GO:0005789 GO:0006986 GO:0018117 GO:0030544 GO:0034976 GO:0042803 GO:0044602 GO:0044603 GO:0051087 GO:0070733 GO:1903894
Reduced folate transporter	P42557	SLC19A1	Cricetulus griseus	10029	1	2',3'-cyclic GMP-AMP binding antiporter activity apical plasma membrane basolateral plasma membrane cyclic-GMP-AMP transmembrane import across plasma membrane cyclic-GMP-AMP transmembrane transporter activity folate import across plasma membrane folate:monoatomic anion antiporter activity folic acid binding methotrexate transmembrane transporter activity	GO:0005542 GO:0008518 GO:0015297 GO:0015350 GO:0016323 GO:0016324 GO:0061507 GO:0140360 GO:0140361 GO:1904447
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	G3I065	I79_016742	Cricetulus griseus	10029	1	Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Exostosin-1	Q9JK82	EXT1	Cricetulus griseus	10029	2	BMP signaling pathway Golgi membrane N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity TNFSF11-mediated signaling pathway antigen processing and presentation axon guidance basement membrane organization blood vessel remodeling bone resorption canonical Wnt signaling pathway cartilage development involved in endochondral bone morphogenesis cell adhesion mediated by integrin cell fate commitment cellular response to virus chondrocyte hypertrophy chondrocyte proliferation chondroitin sulfate metabolic process collagen fibril organization cranial skeletal system development dendrite self-avoidance dendritic cell migration developmental growth involved in morphogenesis embryonic skeletal joint development endochondral bone growth endochondral ossification endoderm development endoplasmic reticulum membrane epithelial tube branching involved in lung morphogenesis fear response fibroblast growth factor receptor signaling pathway fluid transport gastrulation gene expression glandular epithelial cell differentiation glomerular basement membrane development glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity hair follicle morphogenesis heart contraction heart field specification hematopoietic stem cell differentiation hematopoietic stem cell homeostasis hematopoietic stem cell migration to bone marrow heparan sulfate proteoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process heparin biosynthetic process hypersensitivity leukocyte tethering or rolling limb joint morphogenesis lymphocyte adhesion to endothelial cell of high endothelial venule lymphocyte migration into lymphoid organs mesenchymal cell differentiation involved in bone development mesoderm development metal ion binding motor behavior multicellular organism growth multicellular organismal-level water homeostasis neural crest cell differentiation olfactory bulb development optic nerve development ossification involved in bone maturation perichondral bone morphogenesis podocyte differentiation protein catabolic process protein heterodimerization activity protein homodimerization activity protein-containing complex assembly regulation of blood pressure response to heparin response to leukemia inhibitory factor response to light intensity sebaceous gland development smoothened signaling pathway involved in lung development social behavior sodium ion homeostasis stem cell division stomach development sulfation sweat gland development synapse synaptic transmission, glutamatergic tight junction organization vacuole organization vasodilation vocalization behavior wound healing	GO:0000139 GO:0001958 GO:0001974 GO:0002067 GO:0002524 GO:0003128 GO:0003415 GO:0003416 GO:0005789 GO:0007033 GO:0007369 GO:0007411 GO:0007492 GO:0007498 GO:0008217 GO:0008543 GO:0009642 GO:0010467 GO:0014033 GO:0015012 GO:0015014 GO:0017145 GO:0019882 GO:0021554 GO:0021772 GO:0030163 GO:0030199 GO:0030204 GO:0030210 GO:0030509 GO:0031069 GO:0032836 GO:0033627 GO:0035176 GO:0035249 GO:0035264 GO:0035988 GO:0036022 GO:0036336 GO:0036339 GO:0042044 GO:0042060 GO:0042311 GO:0042596 GO:0042803 GO:0043931 GO:0045165 GO:0045202 GO:0045453 GO:0046872 GO:0046982 GO:0048733 GO:0050508 GO:0050509 GO:0050891 GO:0050901 GO:0051923 GO:0055078 GO:0060047 GO:0060070 GO:0060218 GO:0060351 GO:0060441 GO:0060506 GO:0060560 GO:0060792 GO:0061484 GO:0061744 GO:0061974 GO:0062094 GO:0065003 GO:0070593 GO:0071503 GO:0071625 GO:0071711 GO:0071847 GO:0072112 GO:0072498 GO:0097021 GO:0097241 GO:0098586 GO:0120193 GO:1901706 GO:1904888 GO:1990823