GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID Gene Symbol Species Taxonomy ID ▲ No. of Glycosylation Sites GO Labels GO IDs
  • ABCB4
10029
2
  • ABC-type transporter activity
  • ATP binding
  • ATP hydrolysis activity
  • ATPase-coupled transmembrane transporter activity
  • apical plasma membrane
  • bile acid secretion
  • cellular response to bile acid
  • clathrin-coated vesicle
  • cytoplasm
  • lipid homeostasis
  • membrane raft
  • phosphatidylcholine floppase activity
  • plasma membrane
  • positive regulation of cholesterol transport
  • positive regulation of phospholipid translocation
  • positive regulation of phospholipid transport
  • response to fenofibrate
  • GO:0005524
  • GO:0005737
  • GO:0005886
  • GO:0016324
  • GO:0016887
  • GO:0030136
  • GO:0032376
  • GO:0032782
  • GO:0042626
  • GO:0045121
  • GO:0055088
  • GO:0061092
  • GO:0090554
  • GO:0140359
  • GO:1901557
  • GO:1903413
  • GO:2001140
  • TLR2
10029
4
  • Golgi apparatus
  • NAD(P)+ nucleosidase activity
  • NAD+ nucleotidase, cyclic ADP-ribose generating
  • cellular response to diacyl bacterial lipopeptide
  • cellular response to triacyl bacterial lipopeptide
  • inflammatory response
  • innate immune response
  • membrane raft
  • phagocytic vesicle membrane
  • positive regulation of cytokine production
  • regulation of tumor necrosis factor production
  • toll-like receptor signaling pathway
  • transmembrane signaling receptor activity
  • GO:0001819
  • GO:0002224
  • GO:0004888
  • GO:0005794
  • GO:0006954
  • GO:0030670
  • GO:0032680
  • GO:0045087
  • GO:0045121
  • GO:0050135
  • GO:0061809
  • GO:0071726
  • GO:0071727
  • GLG1
10029
5
  • Golgi membrane
  • cytoskeleton
  • GO:0000139
  • GO:0005856
  • I79_015171
10029
1
  • Golgi membrane
  • galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
  • metal ion binding
  • mitochondrial inner membrane
  • mitochondrion organization
  • GO:0000139
  • GO:0005743
  • GO:0007005
  • GO:0015018
  • GO:0046872
  • Pam
10029
1
  • L-ascorbic acid binding
  • copper ion binding
  • peptide metabolic process
  • peptidylamidoglycolate lyase activity
  • peptidylglycine monooxygenase activity
  • transport vesicle membrane
  • GO:0004504
  • GO:0004598
  • GO:0005507
  • GO:0006518
  • GO:0030658
  • GO:0031418
  • POFUT1
10029
2
  • Notch signaling pathway
  • angiogenesis
  • endoplasmic reticulum membrane
  • fucose metabolic process
  • glycosyltransferase activity
  • heart development
  • nervous system development
  • peptide-O-fucosyltransferase activity
  • protein glycosylation
  • regulation of Notch signaling pathway
  • somitogenesis
  • transferase activity
  • GO:0001525
  • GO:0001756
  • GO:0005789
  • GO:0006004
  • GO:0006486
  • GO:0007219
  • GO:0007399
  • GO:0007507
  • GO:0008593
  • GO:0016740
  • GO:0016757
  • GO:0046922
  • PTDSS2
10029
1
  • L-serine-phosphatidylethanolamine phosphatidyltransferase activity
  • endoplasmic reticulum membrane
  • membrane
  • phosphatidylserine biosynthetic process
  • GO:0005789
  • GO:0006659
  • GO:0016020
  • GO:0106245
  • B4GALT4
10029
2
  • Golgi cisterna membrane
  • Golgi membrane
  • N-acetyllactosamine synthase activity
  • UDP-galactosyltransferase activity
  • carbohydrate metabolic process
  • keratan sulfate biosynthetic process
  • lactosylceramide biosynthetic process
  • metal ion binding
  • GO:0000139
  • GO:0001572
  • GO:0003945
  • GO:0005975
  • GO:0018146
  • GO:0032580
  • GO:0035250
  • GO:0046872
  • P2rx1
10029
1
  • ATP binding
  • ceramide biosynthetic process
  • external side of plasma membrane
  • extracellularly ATP-gated monoatomic cation channel activity
  • insemination
  • platelet activation
  • positive regulation of monoatomic ion transport
  • postsynaptic membrane
  • purinergic nucleotide receptor activity
  • regulation of calcium ion transport
  • regulation of vascular associated smooth muscle contraction
  • response to ATP
  • serotonin secretion by platelet
  • GO:0001614
  • GO:0002554
  • GO:0003056
  • GO:0004931
  • GO:0005524
  • GO:0007320
  • GO:0009897
  • GO:0030168
  • GO:0033198
  • GO:0043270
  • GO:0045211
  • GO:0046513
  • GO:0051924
  • B4GALT3
10029
3
  • Golgi cisterna membrane
  • N-acetyllactosamine synthase activity
  • beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
  • carbohydrate metabolic process
  • cytosol
  • galactosylceramide biosynthetic process
  • metal ion binding
  • GO:0003831
  • GO:0003945
  • GO:0005829
  • GO:0005975
  • GO:0006682
  • GO:0032580
  • GO:0046872
Displaying entries 251 - 260 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01