GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
Hyaluronidase	A0A8C2MT53	LOC100758272	Cricetulus griseus	10029	1	carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
Beta-secretase 2	G3HFD5	I79_009291	Cricetulus griseus	10029	2	aspartic-type endopeptidase activity endosome membrane proteolysis	GO:0004190 GO:0005768 GO:0006508 GO:0016020
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A	P97259	MGAT5	Cricetulus griseus	10029	6	Golgi membrane alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity extracellular region manganese ion binding positive regulation of cell migration positive regulation of receptor signaling pathway via STAT protein N-linked glycosylation via asparagine protein phosphatase inhibitor activity	GO:0000139 GO:0004864 GO:0005576 GO:0018279 GO:0030144 GO:0030145 GO:0030335 GO:1904894
Voltage-dependent L-type calcium channel subunit alpha	G3HNB3	I79_012250	Cricetulus griseus	10029	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
P2X purinoceptor	G3HRJ0	I79_013462	Cricetulus griseus	10029	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
N-acetylgalactosamine-6-sulfatase	G3GRS9	I79_000223	Cricetulus griseus	10029	2	N-acetylgalactosamine-6-sulfatase activity lysosome	GO:0005764 GO:0043890
Peptidyl-prolyl cis-trans isomerase A	P14851	PPIA	Cricetulus griseus	10029	1	activation of protein kinase B activity apoptotic process cell adhesion molecule production cellular response to oxidative stress cyclosporin A binding cytoplasm cytosol endothelial cell activation extracellular region heparan sulfate binding integrin binding leukocyte chemotaxis midbody negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway negative regulation of protein K48-linked ubiquitination negative regulation of protein kinase activity negative regulation of protein phosphorylation negative regulation of stress-activated MAPK cascade neutrophil chemotaxis nucleus peptidyl-prolyl cis-trans isomerase activity platelet activation platelet aggregation positive regulation of MAPK cascade positive regulation of NF-kappaB transcription factor activity positive regulation of protein dephosphorylation positive regulation of protein phosphorylation protein folding protein peptidyl-prolyl isomerization regulation of apoptotic signaling pathway regulation of viral genome replication	GO:0000413 GO:0001933 GO:0001934 GO:0003755 GO:0005178 GO:0005576 GO:0005634 GO:0005737 GO:0005829 GO:0006457 GO:0006469 GO:0006915 GO:0016018 GO:0030168 GO:0030496 GO:0030593 GO:0030595 GO:0032148 GO:0032873 GO:0034599 GO:0035307 GO:0042118 GO:0043410 GO:0045069 GO:0051092 GO:0060352 GO:0061944 GO:0070527 GO:1902176 GO:1904399 GO:2001233
Transferrin receptor protein 1	Q07891	TFRC	Cricetulus griseus	10029	5	melanosome plasma membrane positive regulation of B cell proliferation positive regulation of T cell proliferation positive regulation of isotype switching receptor internalization recycling endosome transferrin receptor activity transferrin transport	GO:0004998 GO:0005886 GO:0030890 GO:0031623 GO:0033572 GO:0042102 GO:0042470 GO:0045830 GO:0055037
ATP-dependent translocase ABCB1	P21448	ABCB1	Cricetulus griseus	10029	3	ABC-type xenobiotic transporter activity ATP binding ATP hydrolysis activity apical plasma membrane ceramide floppase activity cytoplasm efflux transmembrane transporter activity floppase activity intercellular canaliculus phosphatidylcholine floppase activity phosphatidylethanolamine flippase activity phospholipid translocation terpenoid transport xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic transport across blood-brain barrier	GO:0005524 GO:0005737 GO:0008559 GO:0015562 GO:0016324 GO:0016887 GO:0045332 GO:0046581 GO:0046865 GO:0090554 GO:0090555 GO:0099038 GO:0140328 GO:1990961 GO:1990962
Beta-secretase 2	A0A061I5J9	H671_4g11418	Cricetulus griseus	10029	2	aspartic-type endopeptidase activity endosome membrane proteolysis	GO:0004190 GO:0005768 GO:0006508 GO:0016020