GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Envelope glycoprotein gp160	P12489	env	Human immunodeficiency virus type 1 (JH3 ISOLATE)	11694	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Envelope glycoprotein gp160	P12487	env	Human immunodeficiency virus type 1 (Z2/CDC-Z34 ISOLATE)	11683	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
EGF-like domain-containing protein comC	Q55AP8	comC	Dictyostelium discoideum	44689	30	membrane	GO:0016020
Envelope glycoprotein gp160	P31819	env	Human immunodeficiency virus type 1 (KB-1 isolate)	36375	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Protocadherin Fat 1	Q14517	FAT1	Homo sapiens	9606	30	actin filament organization anatomical structure morphogenesis apical plasma membrane calcium ion binding cell adhesion cell migration cell-cell adhesion cell-cell junction cell-cell signaling epithelial cell morphogenesis establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis establishment or maintenance of cell polarity extracellular exosome filopodium focal adhesion homophilic cell adhesion via plasma membrane adhesion molecules lamellipodium lens development in camera-type eye nucleus perinuclear region of cytoplasm plasma membrane	GO:0002088 GO:0003382 GO:0003412 GO:0005509 GO:0005634 GO:0005886 GO:0005911 GO:0005925 GO:0007015 GO:0007155 GO:0007156 GO:0007163 GO:0007267 GO:0009653 GO:0016324 GO:0016477 GO:0030027 GO:0030175 GO:0048471 GO:0070062 GO:0098609
Envelope glycoprotein gp160	Q9QBZ0	env	HIV-1 M:F2_MP257C	388823	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Envelope glycoprotein gp160	P03377	env	Human immunodeficiency virus type 1 (BRU ISOLATE)	11686	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Envelope glycoprotein gp160	P03378	env	HIV-1 M:B_ARV2/SF2	11685	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Envelope glycoprotein gp160	P05877	env	HIV-1 M:B_MN	11696	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane identical protein binding membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0042802 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Reticulocyte-binding protein homolog 1	P86148	RH1	Plasmodium falciparum 3D7	36329	30	apical complex bicellular tight junction cell-cell adhesion cytoplasmic vesicle extracellular region heparin binding host cell surface receptor binding membrane mitochondrion plasma membrane rhoptry	GO:0005576 GO:0005739 GO:0005886 GO:0005923 GO:0008201 GO:0016020 GO:0020007 GO:0020008 GO:0031410 GO:0046789 GO:0098609